Novel pharmacological actions of trequinsin hydrochloride improve human sperm cell motility and function

por McBrinn, Rachel C., Fraser, Joanna, Hope, Anthony G., Gray, David W., Barratt, Christopher L.R., Martins da Silva, Sarah J., Brown, Sean G.
Publicado 2019

A Substrate Mimic Allows High-Throughput Assay of the FabA Protein and Consequently the Identification of a Novel Inhibitor of Pseudomonas aeruginosa FabA

por Moynié, Lucile, Hope, Anthony G., Finzel, Kara, Schmidberger, Jason, Leckie, Stuart M., Schneider, Gunter, Burkart, Michael D., Smith, Andrew D., Gray, David W., Naismith, James H.
Publicado 2016

Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-acyl-ACP Reductase from Pseudomonas aeruginosa

por Cukier, Cyprian D., Hope, Anthony G., Elamin, Ayssar A., Moynie, Lucile, Schnell, Robert, Schach, Susanne, Kneuper, Holger, Singh, Mahavir, Naismith, James H., Lindqvist, Ylva, Gray, David W., Schneider, Gunter
Publicado 2013

Drug discovery for male subfertility using high-throughput screening: a new approach to an unsolved problem

por Martins da Silva, Sarah J., Brown, Sean G., Sutton, Keith, King, Louise V., Ruso, Halil, Gray, David W., Wyatt, Paul G., Kelly, Mark C., Barratt, Christopher L.R., Hope, Anthony G.
Publicado 2017

Identifying Inhibitors of Inflammation: A Novel High-Throughput MALDI-TOF Screening Assay for Salt-Inducible Kinases (SIKs)

por Heap, Rachel E., Hope, Anthony G., Pearson, Lesley-Anne, Reyskens, Kathleen M. S. E., McElroy, Stuart P., Hastie, C. James, Porter, David W., Arthur, J. Simon C., Gray, David W., Trost, Matthias
Publicado 2017

Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation

por Kazlauskaite, Agne, Martínez-Torres, R Julio, Wilkie, Scott, Kumar, Atul, Peltier, Julien, Gonzalez, Alba, Johnson, Clare, Zhang, Jinwei, Hope, Anthony G, Peggie, Mark, Trost, Matthias, van Aalten, Daan MF, Alessi, Dario R, Prescott, Alan R, Knebel, Axel, Walden, Helen, Muqit, Miratul MK
Publicado 2015

Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies

por Armstrong, Lee A., Lange, Sven M., Dee Cesare, Virginia, Matthews, Stephen P., Nirujogi, Raja Sekhar, Cole, Isobel, Hope, Anthony, Cunningham, Fraser, Toth, Rachel, Mukherjee, Rukmini, Bojkova, Denisa, Gruber, Franz, Gray, David, Wyatt, Paul G., Cinatl, Jindrich, Dikic, Ivan, Davies, Paul, Kulathu, Yogesh
Publicado 2021