PLAG1 and USF2 Co-regulate Expression of Musashi-2 in Human Hematopoietic Stem and Progenitor Cells

por Belew, Muluken S., Bhatia, Sonam, Keyvani Chahi, Ava, Rentas, Stefan, Draper, Jonathan S., Hope, Kristin J.
Publicado 2018

Assessing the Safety of a Cell-Based Immunotherapy for Brain Cancers Using a Humanized Model of Hematopoiesis

por Salim, Sabra K., Xu, Joshua, Wong, Nicholas, Venugopal, Chitra, Hope, Kristin J., Singh, Sheila K.
Publicado 2020

Musashi-2 Attenuates AHR Signaling to Expand Human Hematopoietic Stem Cells

por Rentas, Stefan, Holzapfel, Nicholas, Belew, Muluken S, Pratt, Gabriel, Voisin, Veronique, Wilhelm, Brian T, Bader, Gary D, Yeo, Gene W, Hope, Kristin J
Publicado 2016

A role for GPx3 in activity of normal and leukemia stem cells

por Herault, Olivier, Hope, Kristin J., Deneault, Eric, Mayotte, Nadine, Chagraoui, Jalila, Wilhelm, Brian T., Cellot, Sonia, Sauvageau, Martin, Andrade-Navarro, Miguel A., Hébert, Josée, Sauvageau, Guy
Publicado 2012

The splicing factor RBM17 drives leukemic stem cell maintenance by evading nonsense-mediated decay of pro-leukemic factors

por Liu, Lina, Vujovic, Ana, Deshpande, Nandan P., Sathe, Shashank, Anande, Govardhan, Chen, He Tian Tony, Xu, Joshua, Minden, Mark D., Yeo, Gene W., Unnikrishnan, Ashwin, Hope, Kristin J., Lu, Yu
Publicado 2022

PLAG1 dampens protein synthesis to promote human hematopoietic stem cell self-renewal

por Keyvani Chahi, Ava, Belew, Muluken S., Xu, Joshua, Chen, He Tian Tony, Rentas, Stefan, Voisin, Veronique, Krivdova, Gabriela, Lechman, Eric, Marhon, Sajid A., De Carvalho, Daniel D., Dick, John E., Bader, Gary D., Hope, Kristin J.
Publicado 2022

In Vivo Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target

por Vujovic, Ana, de Rooij, Laura, Chahi, Ava Keyvani, Chen, He Tian, Yee, Brian A., Loganathan, Sampath K., Liu, Lina, Chan, Derek C.H., Tajik, Amanda, Tsao, Emily, Moreira, Steven, Joshi, Pratik, Xu, Joshua, Wong, Nicholas, Balde, Zaldy, Jahangiri, Soheil, Zandi, Sasan, Aigner, Stefan, Dick, John E., Minden, Mark D., Schramek, Daniel, Yeo, Gene W., Hope, Kristin J.
Publicado 2023

OTUD7A Regulates Neurodevelopmental Phenotypes in the 15q13.3 Microdeletion Syndrome

por Uddin, Mohammed, Unda, Brianna K., Kwan, Vickie, Holzapfel, Nicholas T., White, Sean H., Chalil, Leon, Woodbury-Smith, Marc, Ho, Karen S., Harward, Erin, Murtaza, Nadeem, Dave, Biren, Pellecchia, Giovanna, D’Abate, Lia, Nalpathamkalam, Thomas, Lamoureux, Sylvia, Wei, John, Speevak, Marsha, Stavropoulos, James, Hope, Kristin J., Doble, Brad W., Nielsen, Jacob, Wassman, E. Robert, Scherer, Stephen W., Singh, Karun K.
Publicado 2018