Alterations of EGFR, p53 and PTEN that mimic changes found in basal-like breast cancer promote transformation of human mammary epithelial cells

por Pires, Maira M., Hopkins, Benjamin D., Saal, Lao H., Parsons, Ramon E.
Publicado 2013

Targeting Cullin-RING E3 Ubiquitin Ligase 4 by Small Molecule Modulators

por Wu, Kenneth, Hopkins, Benjamin D., Sanchez, Roberto, DeVita, Robert J., Pan, Zhen-Qiang
Publicado 2021

Precision Targeting of pten-Null Triple-Negative Breast Tumors Guided by Electrophilic Metabolite Sensing

por Liu, Xuyu, Long, Marcus J. C., Hopkins, Benjamin D., Luo, Chaosheng, Wang, Lingxi, Aye, Yimon
Publicado 2020

Rac-Mediated Macropinocytosis of Extracellular Protein Promotes Glucose Independence in Non-Small Cell Lung Cancer

por Hodakoski, Cindy, Hopkins, Benjamin D., Zhang, Guoan, Su, Taojunfeng, Cheng, Zhe, Morris, Roxanne, Rhee, Kyu Y., Goncalves, Marcus D., Cantley, Lewis C.
Publicado 2019

A Functional Precision Oncology Approach to Identify Treatment Strategies for Myxofibrosarcoma Patients

por Pauli, Chantal, De Boni, Lamberto, Pauwels, Jonathan E., Chen, Yanjiang, Planas-Paz, Lara, Shaw, Reid, Emerling, Brooke M., Grandori, Carla, Hopkins, Benjamin D., Rubin, Mark A.
Publicado 2022

Inhibitors of cullin-RING E3 ubiquitin ligase 4 with antitumor potential

por Wu, Kenneth, Huynh, Khoi Q., Lu, Iris, Moustakim, Moses, Miao, Haibin, Yu, Clinton, Haeusgen, Matthew J., Hopkins, Benjamin D., Huang, Lan, Zheng, Ning, Sanchez, Roberto, DeVita, Robert J., Pan, Zhen-Qiang
Publicado 2021

PIP4Ks Suppress Insulin Signaling through a Catalytic-Independent Mechanism

por Wang, Diana G., Paddock, Marcia N., Lundquist, Mark R., Sun, Janet Y., Mashadova, Oksana, Amadiume, Solomon, Bumpus, Timothy W., Hodakoski, Cindy, Hopkins, Benjamin D., Fine, Matthew, Hill, Amanda, Yang, T. Jonathan, Baskin, Jeremy M., Dow, Lukas E., Cantley, Lewis C.
Publicado 2019

Suppression of insulin feedback enhances the efficacy of PI3K inhibitors

por Hopkins, Benjamin D., Pauli, Chantal, Du, Xing, Wang, Diana G., Li, Xiang, Wu, David, Amadiume, Solomon C., Goncalves, Marcus D., Hodakoski, Cindy, Lundquist, Mark R., Bareja, Rohan, Ma, Yan, Harris, Emily M., Sboner, Andrea, Beltran, Himisha, Rubin, Mark A., Mukherjee, Siddhartha, Cantley, Lewis C.
Publicado 2018

PI3K drives the de novo synthesis of coenzyme A from vitamin B5

por Dibble, Christian C., Barritt, Samuel A., Perry, Grace E., Lien, Evan C., Geck, Renee C., DuBois-Coyne, Sarah E., Bartee, David, Zengeya, Thomas T., Cohen, Emily B., Yuan, Min, Hopkins, Benjamin D., Meier, Jordan L., Clohessy, John G., Asara, John M., Cantley, Lewis C., Toker, Alex
Publicado 2022

An atlas of substrate specificities for the human serine/threonine kinome

por Johnson, Jared L., Yaron, Tomer M., Huntsman, Emily M., Kerelsky, Alexander, Song, Junho, Regev, Amit, Lin, Ting-Yu, Liberatore, Katarina, Cizin, Daniel M., Cohen, Benjamin M., Vasan, Neil, Ma, Yilun, Krismer, Konstantin, Robles, Jaylissa Torres, van de Kooij, Bert, van Vlimmeren, Anne E., Andrée-Busch, Nicole, Käufer, Norbert F., Dorovkov, Maxim V., Ryazanov, Alexey G., Takagi, Yuichiro, Kastenhuber, Edward R., Goncalves, Marcus D., Hopkins, Benjamin D., Elemento, Olivier, Taatjes, Dylan J., Maucuer, Alexandre, Yamashita, Akio, Degterev, Alexei, Uduman, Mohamed, Lu, Jingyi, Landry, Sean D., Zhang, Bin, Cossentino, Ian, Linding, Rune, Blenis, John, Hornbeck, Peter V., Turk, Benjamin E., Yaffe, Michael B., Cantley, Lewis C.
Publicado 2023