Alterations of EGFR, p53 and PTEN that mimic changes found in basal-like breast cancer promote transformation of human mammary epithelial cells

ανά Pires, Maira M., Hopkins, Benjamin D., Saal, Lao H., Parsons, Ramon E.
Έκδοση 2013

Targeting Cullin-RING E3 Ubiquitin Ligase 4 by Small Molecule Modulators

ανά Wu, Kenneth, Hopkins, Benjamin D., Sanchez, Roberto, DeVita, Robert J., Pan, Zhen-Qiang
Έκδοση 2021

Precision Targeting of pten-Null Triple-Negative Breast Tumors Guided by Electrophilic Metabolite Sensing

ανά Liu, Xuyu, Long, Marcus J. C., Hopkins, Benjamin D., Luo, Chaosheng, Wang, Lingxi, Aye, Yimon
Έκδοση 2020

Rac-Mediated Macropinocytosis of Extracellular Protein Promotes Glucose Independence in Non-Small Cell Lung Cancer

ανά Hodakoski, Cindy, Hopkins, Benjamin D., Zhang, Guoan, Su, Taojunfeng, Cheng, Zhe, Morris, Roxanne, Rhee, Kyu Y., Goncalves, Marcus D., Cantley, Lewis C.
Έκδοση 2019

A Functional Precision Oncology Approach to Identify Treatment Strategies for Myxofibrosarcoma Patients

ανά Pauli, Chantal, De Boni, Lamberto, Pauwels, Jonathan E., Chen, Yanjiang, Planas-Paz, Lara, Shaw, Reid, Emerling, Brooke M., Grandori, Carla, Hopkins, Benjamin D., Rubin, Mark A.
Έκδοση 2022

Inhibitors of cullin-RING E3 ubiquitin ligase 4 with antitumor potential

ανά Wu, Kenneth, Huynh, Khoi Q., Lu, Iris, Moustakim, Moses, Miao, Haibin, Yu, Clinton, Haeusgen, Matthew J., Hopkins, Benjamin D., Huang, Lan, Zheng, Ning, Sanchez, Roberto, DeVita, Robert J., Pan, Zhen-Qiang
Έκδοση 2021

PIP4Ks Suppress Insulin Signaling through a Catalytic-Independent Mechanism

ανά Wang, Diana G., Paddock, Marcia N., Lundquist, Mark R., Sun, Janet Y., Mashadova, Oksana, Amadiume, Solomon, Bumpus, Timothy W., Hodakoski, Cindy, Hopkins, Benjamin D., Fine, Matthew, Hill, Amanda, Yang, T. Jonathan, Baskin, Jeremy M., Dow, Lukas E., Cantley, Lewis C.
Έκδοση 2019

Suppression of insulin feedback enhances the efficacy of PI3K inhibitors

ανά Hopkins, Benjamin D., Pauli, Chantal, Du, Xing, Wang, Diana G., Li, Xiang, Wu, David, Amadiume, Solomon C., Goncalves, Marcus D., Hodakoski, Cindy, Lundquist, Mark R., Bareja, Rohan, Ma, Yan, Harris, Emily M., Sboner, Andrea, Beltran, Himisha, Rubin, Mark A., Mukherjee, Siddhartha, Cantley, Lewis C.
Έκδοση 2018

PI3K drives the de novo synthesis of coenzyme A from vitamin B5

ανά Dibble, Christian C., Barritt, Samuel A., Perry, Grace E., Lien, Evan C., Geck, Renee C., DuBois-Coyne, Sarah E., Bartee, David, Zengeya, Thomas T., Cohen, Emily B., Yuan, Min, Hopkins, Benjamin D., Meier, Jordan L., Clohessy, John G., Asara, John M., Cantley, Lewis C., Toker, Alex
Έκδοση 2022

An atlas of substrate specificities for the human serine/threonine kinome

ανά Johnson, Jared L., Yaron, Tomer M., Huntsman, Emily M., Kerelsky, Alexander, Song, Junho, Regev, Amit, Lin, Ting-Yu, Liberatore, Katarina, Cizin, Daniel M., Cohen, Benjamin M., Vasan, Neil, Ma, Yilun, Krismer, Konstantin, Robles, Jaylissa Torres, van de Kooij, Bert, van Vlimmeren, Anne E., Andrée-Busch, Nicole, Käufer, Norbert F., Dorovkov, Maxim V., Ryazanov, Alexey G., Takagi, Yuichiro, Kastenhuber, Edward R., Goncalves, Marcus D., Hopkins, Benjamin D., Elemento, Olivier, Taatjes, Dylan J., Maucuer, Alexandre, Yamashita, Akio, Degterev, Alexei, Uduman, Mohamed, Lu, Jingyi, Landry, Sean D., Zhang, Bin, Cossentino, Ian, Linding, Rune, Blenis, John, Hornbeck, Peter V., Turk, Benjamin E., Yaffe, Michael B., Cantley, Lewis C.
Έκδοση 2023