Alterations of EGFR, p53 and PTEN that mimic changes found in basal-like breast cancer promote transformation of human mammary epithelial cells

par Pires, Maira M., Hopkins, Benjamin D., Saal, Lao H., Parsons, Ramon E.
Publié 2013

Targeting Cullin-RING E3 Ubiquitin Ligase 4 by Small Molecule Modulators

par Wu, Kenneth, Hopkins, Benjamin D., Sanchez, Roberto, DeVita, Robert J., Pan, Zhen-Qiang
Publié 2021

Precision Targeting of pten-Null Triple-Negative Breast Tumors Guided by Electrophilic Metabolite Sensing

par Liu, Xuyu, Long, Marcus J. C., Hopkins, Benjamin D., Luo, Chaosheng, Wang, Lingxi, Aye, Yimon
Publié 2020

Rac-Mediated Macropinocytosis of Extracellular Protein Promotes Glucose Independence in Non-Small Cell Lung Cancer

par Hodakoski, Cindy, Hopkins, Benjamin D., Zhang, Guoan, Su, Taojunfeng, Cheng, Zhe, Morris, Roxanne, Rhee, Kyu Y., Goncalves, Marcus D., Cantley, Lewis C.
Publié 2019

A Functional Precision Oncology Approach to Identify Treatment Strategies for Myxofibrosarcoma Patients

par Pauli, Chantal, De Boni, Lamberto, Pauwels, Jonathan E., Chen, Yanjiang, Planas-Paz, Lara, Shaw, Reid, Emerling, Brooke M., Grandori, Carla, Hopkins, Benjamin D., Rubin, Mark A.
Publié 2022

Inhibitors of cullin-RING E3 ubiquitin ligase 4 with antitumor potential

par Wu, Kenneth, Huynh, Khoi Q., Lu, Iris, Moustakim, Moses, Miao, Haibin, Yu, Clinton, Haeusgen, Matthew J., Hopkins, Benjamin D., Huang, Lan, Zheng, Ning, Sanchez, Roberto, DeVita, Robert J., Pan, Zhen-Qiang
Publié 2021

PIP4Ks Suppress Insulin Signaling through a Catalytic-Independent Mechanism

par Wang, Diana G., Paddock, Marcia N., Lundquist, Mark R., Sun, Janet Y., Mashadova, Oksana, Amadiume, Solomon, Bumpus, Timothy W., Hodakoski, Cindy, Hopkins, Benjamin D., Fine, Matthew, Hill, Amanda, Yang, T. Jonathan, Baskin, Jeremy M., Dow, Lukas E., Cantley, Lewis C.
Publié 2019

Suppression of insulin feedback enhances the efficacy of PI3K inhibitors

par Hopkins, Benjamin D., Pauli, Chantal, Du, Xing, Wang, Diana G., Li, Xiang, Wu, David, Amadiume, Solomon C., Goncalves, Marcus D., Hodakoski, Cindy, Lundquist, Mark R., Bareja, Rohan, Ma, Yan, Harris, Emily M., Sboner, Andrea, Beltran, Himisha, Rubin, Mark A., Mukherjee, Siddhartha, Cantley, Lewis C.
Publié 2018

PI3K drives the de novo synthesis of coenzyme A from vitamin B5

par Dibble, Christian C., Barritt, Samuel A., Perry, Grace E., Lien, Evan C., Geck, Renee C., DuBois-Coyne, Sarah E., Bartee, David, Zengeya, Thomas T., Cohen, Emily B., Yuan, Min, Hopkins, Benjamin D., Meier, Jordan L., Clohessy, John G., Asara, John M., Cantley, Lewis C., Toker, Alex
Publié 2022

An atlas of substrate specificities for the human serine/threonine kinome

par Johnson, Jared L., Yaron, Tomer M., Huntsman, Emily M., Kerelsky, Alexander, Song, Junho, Regev, Amit, Lin, Ting-Yu, Liberatore, Katarina, Cizin, Daniel M., Cohen, Benjamin M., Vasan, Neil, Ma, Yilun, Krismer, Konstantin, Robles, Jaylissa Torres, van de Kooij, Bert, van Vlimmeren, Anne E., Andrée-Busch, Nicole, Käufer, Norbert F., Dorovkov, Maxim V., Ryazanov, Alexey G., Takagi, Yuichiro, Kastenhuber, Edward R., Goncalves, Marcus D., Hopkins, Benjamin D., Elemento, Olivier, Taatjes, Dylan J., Maucuer, Alexandre, Yamashita, Akio, Degterev, Alexei, Uduman, Mohamed, Lu, Jingyi, Landry, Sean D., Zhang, Bin, Cossentino, Ian, Linding, Rune, Blenis, John, Hornbeck, Peter V., Turk, Benjamin E., Yaffe, Michael B., Cantley, Lewis C.
Publié 2023