Alterations of EGFR, p53 and PTEN that mimic changes found in basal-like breast cancer promote transformation of human mammary epithelial cells

de réir Pires, Maira M., Hopkins, Benjamin D., Saal, Lao H., Parsons, Ramon E.
Foilsithe / Cruthaithe 2013

Targeting Cullin-RING E3 Ubiquitin Ligase 4 by Small Molecule Modulators

de réir Wu, Kenneth, Hopkins, Benjamin D., Sanchez, Roberto, DeVita, Robert J., Pan, Zhen-Qiang
Foilsithe / Cruthaithe 2021

Precision Targeting of pten-Null Triple-Negative Breast Tumors Guided by Electrophilic Metabolite Sensing

de réir Liu, Xuyu, Long, Marcus J. C., Hopkins, Benjamin D., Luo, Chaosheng, Wang, Lingxi, Aye, Yimon
Foilsithe / Cruthaithe 2020

Rac-Mediated Macropinocytosis of Extracellular Protein Promotes Glucose Independence in Non-Small Cell Lung Cancer

de réir Hodakoski, Cindy, Hopkins, Benjamin D., Zhang, Guoan, Su, Taojunfeng, Cheng, Zhe, Morris, Roxanne, Rhee, Kyu Y., Goncalves, Marcus D., Cantley, Lewis C.
Foilsithe / Cruthaithe 2019

A Functional Precision Oncology Approach to Identify Treatment Strategies for Myxofibrosarcoma Patients

de réir Pauli, Chantal, De Boni, Lamberto, Pauwels, Jonathan E., Chen, Yanjiang, Planas-Paz, Lara, Shaw, Reid, Emerling, Brooke M., Grandori, Carla, Hopkins, Benjamin D., Rubin, Mark A.
Foilsithe / Cruthaithe 2022

Inhibitors of cullin-RING E3 ubiquitin ligase 4 with antitumor potential

de réir Wu, Kenneth, Huynh, Khoi Q., Lu, Iris, Moustakim, Moses, Miao, Haibin, Yu, Clinton, Haeusgen, Matthew J., Hopkins, Benjamin D., Huang, Lan, Zheng, Ning, Sanchez, Roberto, DeVita, Robert J., Pan, Zhen-Qiang
Foilsithe / Cruthaithe 2021

PIP4Ks Suppress Insulin Signaling through a Catalytic-Independent Mechanism

de réir Wang, Diana G., Paddock, Marcia N., Lundquist, Mark R., Sun, Janet Y., Mashadova, Oksana, Amadiume, Solomon, Bumpus, Timothy W., Hodakoski, Cindy, Hopkins, Benjamin D., Fine, Matthew, Hill, Amanda, Yang, T. Jonathan, Baskin, Jeremy M., Dow, Lukas E., Cantley, Lewis C.
Foilsithe / Cruthaithe 2019

Suppression of insulin feedback enhances the efficacy of PI3K inhibitors

de réir Hopkins, Benjamin D., Pauli, Chantal, Du, Xing, Wang, Diana G., Li, Xiang, Wu, David, Amadiume, Solomon C., Goncalves, Marcus D., Hodakoski, Cindy, Lundquist, Mark R., Bareja, Rohan, Ma, Yan, Harris, Emily M., Sboner, Andrea, Beltran, Himisha, Rubin, Mark A., Mukherjee, Siddhartha, Cantley, Lewis C.
Foilsithe / Cruthaithe 2018

PI3K drives the de novo synthesis of coenzyme A from vitamin B5

de réir Dibble, Christian C., Barritt, Samuel A., Perry, Grace E., Lien, Evan C., Geck, Renee C., DuBois-Coyne, Sarah E., Bartee, David, Zengeya, Thomas T., Cohen, Emily B., Yuan, Min, Hopkins, Benjamin D., Meier, Jordan L., Clohessy, John G., Asara, John M., Cantley, Lewis C., Toker, Alex
Foilsithe / Cruthaithe 2022

An atlas of substrate specificities for the human serine/threonine kinome

de réir Johnson, Jared L., Yaron, Tomer M., Huntsman, Emily M., Kerelsky, Alexander, Song, Junho, Regev, Amit, Lin, Ting-Yu, Liberatore, Katarina, Cizin, Daniel M., Cohen, Benjamin M., Vasan, Neil, Ma, Yilun, Krismer, Konstantin, Robles, Jaylissa Torres, van de Kooij, Bert, van Vlimmeren, Anne E., Andrée-Busch, Nicole, Käufer, Norbert F., Dorovkov, Maxim V., Ryazanov, Alexey G., Takagi, Yuichiro, Kastenhuber, Edward R., Goncalves, Marcus D., Hopkins, Benjamin D., Elemento, Olivier, Taatjes, Dylan J., Maucuer, Alexandre, Yamashita, Akio, Degterev, Alexei, Uduman, Mohamed, Lu, Jingyi, Landry, Sean D., Zhang, Bin, Cossentino, Ian, Linding, Rune, Blenis, John, Hornbeck, Peter V., Turk, Benjamin E., Yaffe, Michael B., Cantley, Lewis C.
Foilsithe / Cruthaithe 2023