Quantitative proteomic analyses of dynamic signalling events in cortical neurons undergoing excitotoxic cell death

por Hoque, Ashfaqul, Williamson, Nicholas A., Ameen, S. Sadia, Ciccotosto, Giuseppe D., Hossain, M. Iqbal, Oakhill, Jonathan S., Ng, Dominic C. H., Ang, Ching-Seng, Cheng, Heung-Chin
Publicado 2019

The eEF2 kinase-induced STAT3 inactivation inhibits lung cancer cell proliferation by phosphorylation of PKM2

por Xiao, Min, Xie, Jianling, Wu, Yu, Wang, Genzhu, Qi, Xin, Liu, Zailiang, Wang, Yuying, Wang, Xuemin, Hoque, Ashfaqul, Oakhill, Jon, Proud, Christopher G., Li, Jing
Publicado 2020

Impact of Genetic Variation on Human CaMKK2 Regulation by Ca(2+)-Calmodulin and Multisite Phosphorylation

por O’Brien, Matthew T., Oakhill, Jonathan S., Ling, Naomi X. Y., Langendorf, Christopher G., Hoque, Ashfaqul, Dite, Toby A., Means, Anthony R., Kemp, Bruce E., Scott, John W.
Publicado 2017

The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs

por Dite, Toby A., Ling, Naomi X. Y., Scott, John W., Hoque, Ashfaqul, Galic, Sandra, Parker, Benjamin L., Ngoei, Kevin R. W., Langendorf, Christopher G., O’Brien, Matthew T., Kundu, Mondira, Viollet, Benoit, Steinberg, Gregory R., Sakamoto, Kei, Kemp, Bruce E., Oakhill, Jonathan S.
Publicado 2017

mTORC1 directly inhibits AMPK to promote cell proliferation under nutrient stress

por Ling, Naomi X.Y., Kaczmarek, Adrian, Hoque, Ashfaqul, Davie, Elizabeth, Ngoei, Kevin R.W., Morrison, Kaitlin R., Smiles, William J., Forte, Gabriella M., Wang, Tingting, Lie, Shervi, Dite, Toby A., Langendorf, Christopher G., Scott, John W., Oakhill, Jonathan S., Petersen, Janni
Publicado 2020

Mitochondrial fission protein Drp1 inhibition promotes cardiac mesodermal differentiation of human pluripotent stem cells

por Hoque, Ashfaqul, Sivakumaran, Priyadharshini, Bond, Simon T., Ling, Naomi X. Y., Kong, Anne M., Scott, John W., Bandara, Nadeeka, Hernández, Damián, Liu, Guei-Sheung, Wong, Raymond C. B., Ryan, Michael T., Hausenloy, Derek J., Kemp, Bruce E., Oakhill, Jonathan S., Drew, Brian G., Pébay, Alice, Lim, Shiang Y.
Publicado 2018

Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1-isoforms

por Pinkosky, Stephen L., Scott, John W., Desjardins, Eric M., Smith, Brennan K., Day, Emily A., Ford, Rebecca J., Langendorf, Christopher G., Ling, Naomi X. Y., Nero, Tracy L., Loh, Kim, Galic, Sandra, Hoque, Ashfaqul, Smiles, William J., Ngoei, Kevin R.W., Parker, Michael W., Yan, Yan, Melcher, Karsten, Kemp, Bruce E., Oakhill, Jonathan S., Steinberg, Gregory R.
Publicado 2020

N-Terminomic Changes in Neurons During Excitotoxicity Reveal Proteolytic Events Associated With Synaptic Dysfunctions and Potential Targets for Neuroprotection

por Ameen, S. Sadia, Griem-Krey, Nane, Dufour, Antoine, Hossain, M. Iqbal, Hoque, Ashfaqul, Sturgeon, Sharelle, Nandurkar, Harshal, Draxler, Dominik F., Medcalf, Robert L., Kamaruddin, Mohd Aizuddin, Lucet, Isabelle S., Leeming, Michael G., Liu, Dazhi, Dhillon, Amardeep, Lim, Jet Phey, Basheer, Faiza, Zhu, Hong-Jian, Bokhari, Laita, Roulston, Carli L., Paradkar, Prasad N., Kleifeld, Oded, Clarkson, Andrew N., Wellendorph, Petrine, Ciccotosto, Giuseppe D., Williamson, Nicholas A., Ang, Ching-Seng, Cheng, Heung-Chin
Publicado 2023