Single-cell analysis of immune cell transcriptome during HIV-1 infection and therapy

por Pollara, Justin, Khanal, Santosh, Edwards, R. Whitney, Hora, Bhavna, Ferrari, Guido, Haynes, Barton F., Bradley, Todd
Publicado 2022

Transmission of Multiple HIV-1 Subtype C Transmitted/founder Viruses into the Same Recipients Was not Determined by Modest Phenotypic Differences

por Song, Hongshuo, Hora, Bhavna, Giorgi, Elena E., Kumar, Amit, Cai, Fangping, Bhattacharya, Tanmoy, Perelson, Alan S., Gao, Feng
Publicado 2016

IMMU-27. ANALYSIS OF IMMUNE SIGNATURES IN PEDIATRIC GLIOBLASTOMAS FOR PATIENT STRATIFICATION TO IMMUNOTHERAPY

por Chandramohan, Vidyalakshmi, Evangelous, Tyler, Lipp, Eric S, Hora, Bhavna, Bigner, Darell D, McLendon, Roger E, Ashley, David M
Publicado 2020

Reversion and T Cell Escape Mutations Compensate the Fitness Loss of a CD8(+) T Cell Escape Mutant in Their Cognate Transmitted/Founder Virus

por Song, Hongshuo, Hora, Bhavna, Bhattacharya, Tanmoy, Goonetilleke, Nilu, Liu, Michael K. P., Wiehe, Kevin, Li, Hui, Iyer, Shilpa S., McMichael, Andrew J., Perelson, Alan S., Gao, Feng
Publicado 2014

Preexisting compensatory amino acids compromise fitness costs of a HIV-1 T cell escape mutation

por Liu, Donglai, Zuo, Tao, Hora, Bhavna, Song, Hongshuo, Kong, Wei, Yu, Xianghui, Goonetilleke, Nilu, Bhattacharya, Tanmoy, Perelson, Alan S, Haynes, Barton F, McMichael, Andrew J, Gao, Feng
Publicado 2014

A strongly selected mutation in the HIV-1 genome is independent of T cell responses and neutralizing antibodies

por Liu, Donglai, Wang, Chu, Hora, Bhavna, Zuo, Tao, Goonetilleke, Nilu, Liu, Michael K. P., Berrong, Mark, Ferrari, Guido, McMichael, Andrew J., Bhattacharya, Tanmoy, Perelson, Alan S., Gao, Feng
Publicado 2017

Increased predominance of HIV-1 CRF01_AE and its recombinants in the Philippines

por Chen, Yue, Hora, Bhavna, DeMarco, Todd, Berba, Regina, Register, Heidi, Hood, Sylvia, Carter, Meredith, Stone, Mars, Pappas, Andrea, Sanchez, Ana M., Busch, Michael, Denny, Thomas N., Gao, Feng
Publicado 2019

Vaccination with a replication-defective cytomegalovirus vaccine elicits a glycoprotein B-specific monoclonal antibody repertoire distinct from natural infection

por Valencia, Sarah M., Rochat, Eric, Harnois, Melissa J., Dennis, Maria, Webster, Helen S., Hora, Bhavna, Kumar, Amit, Wang, Hsuan-Yuan (Sherry), Li, Leike, Freed, Daniel, Zhang, Ningyan, An, Zhiqiang, Wang, Dai, Permar, Sallie R.
Publicado 2023

Long-Term Recovery of the Adaptive Immune System in Rhesus Macaques After Total Body Irradiation

por Macintyre, Andrew N., French, Matthew J., Sanders, Brittany R., Riebe, Kristina J., Shterev, Ivo D., Wiehe, Kevin, Hora, Bhavna, Evangelous, Tyler, Dugan, Greg, Bourland, J. Daniel, Cline, J. Mark, Sempowski, Gregory D.
Publicado 2021

Fast Dissemination of New HIV-1 CRF02/A1 Recombinants in Pakistan

por Chen, Yue, Hora, Bhavna, DeMarco, Todd, Shah, Sharaf Ali, Ahmed, Manzoor, Sanchez, Ana M., Su, Chang, Carter, Meredith, Stone, Mars, Hasan, Rumina, Hasan, Zahra, Busch, Michael P., Denny, Thomas N., Gao, Feng
Publicado 2016

Streamlined Subpopulation, Subtype, and Recombination Analysis of HIV-1 Half-Genome Sequences Generated by High-Throughput Sequencing

por Hora, Bhavna, Gulzar, Naila, Chen, Yue, Karagiannis, Konstantinos, Cai, Fangping, Su, Chang, Smith, Krista, Simonyan, Vahan, Shah, Sharaf Ali, Ahmed, Manzoor, Sanchez, Ana M., Stone, Mars, Cohen, Myron S., Denny, Thomas N., Mazumder, Raja, Gao, Feng
Publicado 2020

A single, improbable B cell receptor mutation confers potent neutralization against cytomegalovirus

por Jenks, Jennifer A., Amin, Sharmi, Sponholtz, Madeline R., Kumar, Amit, Wrapp, Daniel, Venkatayogi, Sravani, Tu, Joshua J., Karthigeyan, Krithika, Valencia, Sarah M., Connors, Megan, Harnois, Melissa J., Hora, Bhavna, Rochat, Eric, McLellan, Jason S., Wiehe, Kevin, Permar, Sallie R.
Publicado 2023

A CD4-mimetic compound enhances vaccine efficacy against stringent immunodeficiency virus challenge

por Madani, Navid, Princiotto, Amy M., Mach, Linh, Ding, Shilei, Prevost, Jérémie, Richard, Jonathan, Hora, Bhavna, Sutherland, Laura, Zhao, Connie A., Conn, Brandon P., Bradley, Todd, Moody, M. Anthony, Melillo, Bruno, Finzi, Andrés, Haynes, Barton F., Smith III, Amos B., Santra, Sampa, Sodroski, Joseph
Publicado 2018

RAB11FIP5-Deficient Mice Exhibit Cytokine-Related Transcriptomic Signatures

por Li, Dapeng, Bradley, Todd, Cain, Derek W., Pedroza-Pacheco, Isabela, Aggelakopoulou, Maria, Parks, Robert, Barr, Maggie, Xia, Shi-Mao, Scearce, Richard, Bowman, Cindy, Stevens, Grace, Newman, Amanda, Hora, Bhavna, Chen, Yue, Riebe, Kristina, Wang, Yunfei, Sempowski, Gregory, Saunders, Kevin O., Borrow, Persephone, Haynes, Barton F.
Publicado 2020

Host immunity associated with spontaneous suppression of viremia in therapy-naïve young rhesus macaques following neonatal SHIV infection

por Evangelous, Tyler D., Berry, Madison, Venkatayogi, Sravani, LeMaster, Cas, Geanes, Eric S., De Naeyer, Nicole, DeMarco, Todd, Shen, Xiaoying, Li, Hui, Hora, Bhavna, Solomonis, Nicholas, Misamore, Johnathan, Lewis, Mark G., Denny, Thomas N., Montefiori, David, Shaw, George M., Wiehe, Kevin, Bradley, Todd, Williams, Wilton B.
Publicado 2023

Genetic Characterization of a Panel of Diverse HIV-1 Isolates at Seven International Sites

por Hora, Bhavna, Keating, Sheila M., Chen, Yue, Sanchez, Ana M., Sabino, Ester, Hunt, Gillian, Ledwaba, Johanna, Hackett, John, Swanson, Priscilla, Hewlett, Indira, Ragupathy, Viswanath, Vikram Vemula, Sai, Zeng, Peibin, Tee, Kok-Keng, Chow, Wei Zhen, Ji, Hezhao, Sandstrom, Paul, Denny, Thomas N., Busch, Michael P., Gao, Feng
Publicado 2016

Polyclonal Broadly Neutralizing Antibody Activity Characterized by CD4 Binding Site and V3-Glycan Antibodies in a Subset of HIV-1 Virus Controllers

por Nyanhete, Tinashe E., Edwards, Robert J., LaBranche, Celia C., Mansouri, Katayoun, Eaton, Amanda, Dennison, S. Moses, Saunders, Kevin O., Goodman, Derrick, Janowska, Katarzyna, Spreng, Rachel L., Zhang, Lu, Mudrak, Sarah V., Hope, Thomas J., Hora, Bhavna, Bradley, Todd, Georgiev, Ivelin S., Montefiori, David C., Acharya, Priyamvada, Tomaras, Georgia D.
Publicado 2021

RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses

por Bradley, Todd, Peppa, Dimitra, Pedroza-Pacheco, Isabela, Li, Dapeng, Cain, Derek W., Henao, Ricardo, Venkat, Vaishnavi, Hora, Bhavna, Chen, Yue, Vandergrift, Nathan A., Overman, R. Glenn, Edwards, R. Whitney, Woods, Chris W., Tomaras, Georgia D., Ferrari, Guido, Ginsburg, Geoffrey S., Connors, Mark, Cohen, Myron S., Moody, M. Anthony, Borrow, Persephone, Haynes, Barton F.
Publicado 2018

Impact of immune escape mutations on HIV-1 fitness in the context of the cognate transmitted/founder genome

por Song, Hongshuo, Pavlicek, Jeffrey W, Cai, Fangping, Bhattacharya, Tanmoy, Li, Hui, Iyer, Shilpa S, Bar, Katharine J, Decker, Julie M, Goonetilleke, Nilu, Liu, Michael KP, Berg, Anna, Hora, Bhavna, Drinker, Mark S, Eudailey, Josh, Pickeral, Joy, Moody, M Anthony, Ferrari, Guido, McMichael, Andrew, Perelson, Alan S, Shaw, George M, Hahn, Beatrice H, Haynes, Barton F, Gao, Feng
Publicado 2012

Neonatal SHIV infection in rhesus macaques elicited heterologous HIV-1-neutralizing antibodies

por Hora, Bhavna, Li, Hui, Shen, Xiaoying, Martin, Mitchell, Chen, Yue, Berry, Madison, Evangelous, Tyler, Macintyre, Andrew N., Arus-Altuz, Aria, Wang, Shuyi, Singh, Ajay, Zhao, Chengyan, De Naeyer, Nicole, DeMarco, Todd, Kuykendall, Cindy, Gurley, Thaddeus, Saunders, Kevin O., Denny, Thomas, Moody, M. Anthony, Misamore, John, Lewis, Mark G., Wiehe, Kevin, Cain, Derek W., Montefiori, David C., Shaw, George M., Williams, Wilton B.
Publicado 2023