A High-Dimensional Window into the Micro-Environment of Triple Negative Breast Cancer

por Nederlof, Iris, Horlings, Hugo M., Curtis, Christina, Kok, Marleen
Publicado 2021

Low grade serous carcinoma of the peritoneum in a BRCA1 carrier previously diagnosed with a “low-grade serous tubal intra-epithelial carcinoma” (STIC) on risk reducing surgery

por Chay, Wen Yee, Horlings, Hugo M., Tinker, Anna V., Gelmon, Karen A., Gilks, C.Blake
Publicado 2015

Integration of Clinical and Gene Expression Data Has a Synergetic Effect on Predicting Breast Cancer Outcome

por van Vliet, Martin H., Horlings, Hugo M., van de Vijver, Marc J., Reinders, Marcel J. T., Wessels, Lodewyk F. A.
Publicado 2012

Pooling breast cancer datasets has a synergetic effect on classification performance and improves signature stability

por van Vliet, Martin H, Reyal, Fabien, Horlings, Hugo M, van de Vijver, Marc J, Reinders, Marcel JT, Wessels, Lodewyk FA
Publicado 2008

Retrospective analysis of metastatic behaviour of breast cancer subtypes

por Savci-Heijink, C. Dilara, Halfwerk, Hans, Hooijer, Gerrit K. J., Horlings, Hugo M., Wesseling, Jelle, van de Vijver, Marc J.
Publicado 2015

Potential importance of protease activated receptor (PAR)-1 expression in the tumor stroma of non-small-cell lung cancer

por Lin, Cong, Majoor, Christof J., Roelofs, Joris J. T. H., de Kruif, Martijn D., Horlings, Hugo M., Borensztajn, Keren, Spek, C. Arnold
Publicado 2017

SIRAC: Supervised Identification of Regions of Aberration in aCGH datasets

por Lai, Carmen, Horlings, Hugo M, van de Vijver, Marc J, van Beers, Eric H, Nederlof, Petra M, Wessels, Lodewyk FA, Reinders, Marcel JT
Publicado 2007

BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations

por Holstege, Henne, Horlings, Hugo M, Velds, Arno, Langerød, Anita, Børresen-Dale, Anne-Lise, van de Vijver, Marc J, Nederlof, Petra M, Jonkers, Jos
Publicado 2010

Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets

por Farazi, Thalia A, ten Hoeve, Jelle J, Brown, Miguel, Mihailovic, Aleksandra, Horlings, Hugo M, van de Vijver, Marc J, Tuschl, Thomas, Wessels, Lodewyk FA
Publicado 2014

Immune landscape of breast tumors with low and intermediate estrogen receptor expression

por Voorwerk, Leonie, Sanders, Joyce, Keusters, Milou S., Balduzzi, Sara, Cornelissen, Sten, Duijst, Maxime, Lips, Esther H., Sonke, Gabe S., Linn, Sabine C., Horlings, Hugo M., Kok, Marleen
Publicado 2023

Spatial interplay of tissue hypoxia and T-cell regulation in ductal carcinoma in situ

por Sobhani, Faranak, Muralidhar, Sathya, Hamidinekoo, Azam, Hall, Allison H., King, Lorraine M., Marks, Jeffrey R., Maley, Carlo, Horlings, Hugo M., Hwang, E. Shelley, Yuan, Yinyin
Publicado 2022

EZH2 and BMI1 inversely correlate with prognosis and TP53 mutation in breast cancer

por Pietersen, Alexandra M, Horlings, Hugo M, Hauptmann, Michael, Langerød, Anita, Ajouaou, Abderrahim, Cornelissen-Steijger, Paulien, Wessels, Lodewijk F, Jonkers, Jos, Vijver, Marc J van de, van Lohuizen, Maarten
Publicado 2008

RadioLOGIC, a healthcare model for processing electronic health records and decision-making in breast disease

por Zhang, Tianyu, Tan, Tao, Wang, Xin, Gao, Yuan, Han, Luyi, Balkenende, Luuk, D’Angelo, Anna, Bao, Lingyun, Horlings, Hugo M., Teuwen, Jonas, Beets-Tan, Regina G.H., Mann, Ritse M.
Publicado 2023

Predicting breast cancer types on and beyond molecular level in a multi-modal fashion

por Zhang, Tianyu, Tan, Tao, Han, Luyi, Appelman, Linda, Veltman, Jeroen, Wessels, Ronni, Duvivier, Katya M., Loo, Claudette, Gao, Yuan, Wang, Xin, Horlings, Hugo M., Beets-Tan, Regina G. H., Mann, Ritse M.
Publicado 2023

Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity

por Léveillé, Nicolas, Elkon, Ran, Davalos, Veronica, Manoharan, Vijayalaxmi, Hollingworth, Dave, Vrielink, Joachim Oude, le Sage, Carlos, Melo, Carlos A., Horlings, Hugo M., Wesseling, Jelle, Ule, Jernej, Esteller, Manel, Ramos, Andres, Agami, Reuven
Publicado 2011

Sorafenib synergizes with metformin in NSCLC through AMPK pathway activation

por Groenendijk, Floris H, Mellema, Wouter W, van der Burg, Eline, Schut, Eva, Hauptmann, Michael, Horlings, Hugo M, Willems, Stefan M, van den Heuvel, Michel M, Jonkers, Jos, Smit, Egbert F, Bernards, René
Publicado 2015

Identification of breast cancer cell subtypes sensitive to ATG4B inhibition

por Bortnik, Svetlana, Choutka, Courtney, Horlings, Hugo M., Leung, Samuel, Baker, Jennifer H., Lebovitz, Chandra, Dragowska, Wieslawa H., Go, Nancy E., Bally, Marcel B., Minchinton, Andrew I., Gelmon, Karen A., Gorski, Sharon M.
Publicado 2016

Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets

por Turner, Nicholas, Lambros, Maryou B, Horlings, Hugo M., Pearson, Alex, Sharpe, Rachel, Natrajan, Rachael, Geyer, Felipe C, van Kouwenhove, Marieke, Kreike, Bas, Mackay, Alan, Ashworth, Alan, van de Vijver, Marc J, Reis-Filho, Jorge S
Publicado 2010

Functional Profiling of FSH and Estradiol in Ovarian Granulosa Cell Tumors

por Haltia, Ulla-Maija, Pihlajoki, Marjut, Andersson, Noora, Mäkinen, Lotta, Tapper, Johanna, Cervera, Alejandra, Horlings, Hugo M, Turpeinen, Ursula, Anttonen, Mikko, Bützow, Ralf, Unkila-Kallio, Leila, Carpén, Olli, Wilson, David B, Heikinheimo, Markku, Färkkilä, Anniina
Publicado 2020

Systematic analysis of somatic mutations impacting gene expression in 12 tumour types

por Ding, Jiarui, McConechy, Melissa K., Horlings, Hugo M., Ha, Gavin, Chun Chan, Fong, Funnell, Tyler, Mullaly, Sarah C., Reimand, Jüri, Bashashati, Ali, Bader, Gary D., Huntsman, David, Aparicio, Samuel, Condon, Anne, Shah, Sohrab P.
Publicado 2015