A point-of-care pharmacokinetic/pharmacodynamic trial in critically ill children: Study design and feasibility

por Thompson, Elizabeth J., Foote, Henry P., Hill, Kevin D., Hornik, Christoph P.
Publicado 2023

How to Conduct Clinical Trials in Children: A Tutorial

por Shakhnovich, Valentina, Hornik, Christoph P., Kearns, Gregory L., Weigel, Jaylene, Abdel‐Rahman, Susan M.
Publicado 2019

Bringing research directly to families in the era of COVID-19

por Balevic, Stephen J., Singler, Lindsay, Randell, Rachel, Chung, Richard J., Lemmon, Monica E., Hornik, Christoph P.
Publicado 2020

Pharmacokinetics Alterations in Critically Ill Pediatric Patients on Extracorporeal Membrane Oxygenation: A Systematic Review

por Sutiman, Natalia, Koh, Janine Cynthia, Watt, Kevin, Hornik, Christoph, Murphy, Beverly, Chan, Yoke Hwee, Lee, Jan Hau
Publicado 2020

Safety of sildenafil in premature infants with severe bronchopulmonary dysplasia (SILDI-SAFE): a multicenter, randomized, placebo-controlled, sequential dose-escalating, double-mas...

por Schneider, Simone, Bailey, Mary, Spears, Tracy, Esther, Charles R., Laughon, Matthew M., Hornik, Christoph P., Jackson, Wesley
Publicado 2020

Population Pharmacokinetic/Pharmacodynamic Modeling of Methylprednisolone in Neonates Undergoing Cardiopulmonary Bypass

por Hornik, Christoph P., Gonzalez, Daniel, Dumond, Julie, Wu, Huali, Graham, Eric M., Hill, Kevin D., Cohen‐Wolkowiez, Michael
Publicado 2019

Development of an Adult Physiologically Based Pharmacokinetic Model of Solithromycin in Plasma and Epithelial Lining Fluid

por Salerno, Sara N., Edginton, Andrea, Cohen‐Wolkowiez, Michael, Hornik, Christoph P., Watt, Kevin M., Jamieson, Brian D., Gonzalez, Daniel
Publicado 2017

Delivering clinical trials at home: protocol, design and implementation of a direct-to-family paediatric lupus trial

por Randell, Rachel L, Singler, Lindsay, Cunningham, Anthony, Schanberg, Laura E, Cohen-Wolkowiez, Michael, Hornik, Christoph P, Balevic, Stephen J
Publicado 2021

Power analysis for idiographic (within-subject) clinical trials: Implications for treatments of rare conditions and precision medicine

por Tueller, Stephen, Ramirez, Derek, Cance, Jessica D., Ye, Ai, Wheeler, Anne C., Fan, Zheng, Hornik, Christoph, Ridenour, Ty A.
Publicado 2022

Sildenafil and Retinopathy of Prematurity Risk in Very Low Birth Weight Infants

por Samiee-Zafarghandy, Samira, van den Anker, John N., Laughon, Matthew M., Clark, Reese H., Smith, P. Brian, Hornik, Christoph P.
Publicado 2015

Pharmacokinetics of hydroxychloroquine in paediatric lupus: data from a novel, direct-to-family clinical trial

por Balevic, Stephen J, Randell, Rachel, Weiner, Daniel, Beard, Claire, Schanberg, Laura Eve, Hornik, Christoph P, Cohen-Wolkowiez, Michael, Gonzalez, Daniel
Publicado 2022

Association of Urine Biomarkers With Acute Kidney Injury and Fluid Overload in Infants After Cardiac Surgery: A Single Center Ancillary Cohort of the Steroids to Reduce Systemic In...

por Thompson, Elizabeth J., Chamberlain, Reid C., Hill, Kevin D., Sullenger, Rebecca D., Graham, Eric M., Gbadegesin, Rasheed A., Hornik, Christoph P.
Publicado 2023

Association of in utero magnesium exposure and spontaneous intestinal perforations in extremely low birth weight infants

por Downey, L. Corbin, Cotten, C. Michael, Hornik, Christoph P., Laughon, Matthew M., Tolia, Veeral N., Clark, Reese H., Smith, P. Brian
Publicado 2017

Estimation of Body Fat Percentage for Clinical Pharmacokinetic Studies in Children

por Green, Thomas P., Binns, Helen J., Wu, Huali, Ariza, Adolfo J., Perrin, Eliana M., Quadri, Maheen, Hornik, Christoph P., Cohen‐Wolkowiez, Michael
Publicado 2020

Association between simulated ketamine exposures and oxygen saturations in children

por Commander, Sarah Jane, Gonzalez, Daniel, Kumar, Karan R, Spears, Tracy, Cohen-Wolkowiez, Michael, Zimmerman, Kanecia O, Lee, Jan Hau, Hornik, Christoph P
Publicado 2023

Using Pharmacokinetic Modeling and Electronic Health Record Data to Predict Clinical and Safety Outcomes after Methylprednisolone Exposure during Cardiopulmonary Bypass in Neonates

por Foote, Henry P., Wu, Huali, Balevic, Stephen J., Thompson, Elizabeth J., Hill, Kevin D., Graham, Eric M., Hornik, Christoph P., Kumar, Karan R.
Publicado 2023

Hydroxychloroquine PK and exposure-response in pregnancies with lupus: the importance of adherence for neonatal outcomes

por Balevic, Stephen J, Weiner, Daniel, Clowse, Megan E B, Eudy, Amanda M, Maharaj, Anil R, Hornik, Christoph P, Cohen-Wolkowiez, Michael, Gonzalez, Daniel
Publicado 2022

Pharmacokinetics of Oral Vitamin D in Children with Obesity and Asthma

por Lang, Jason E., Ramirez, Rodrigo Gonzalez, Balevic, Stephen, Bickel, Scott, Hornik, Christoph P., Majure, J. Marc, Venkatachalam, Saranya, Snowden, Jessica, O’Sullivan, Brian, James, Laura
Publicado 2023

Increasing access and uptake of SARS-CoV-2 at-home tests using a community-engaged approach

por D'Agostino, Emily M., Corbie, Giselle, Kibbe, Warren A., Hornik, Christoph P., Richmond, Al, Dunston, Angella, Damman, Allyn, Wruck, Lisa, Alvarado, Manuel, Cohen-Wolkowiez, Michael
Publicado 2022

Safety of sildenafil in premature infants at risk of bronchopulmonary dysplasia: Rationale and methods of a phase II randomized trial

por Lang, Jason E., Hornik, Chi D., Martz, Karen, Jacangelo, Juliana, Anand, Ravinder, Greenberg, Rachel, Hornik, Christoph, Zimmerman, Kanecia, Smith, P. Brian, Benjamin, Daniel K., Laughon, Matthew
Publicado 2022