mRNA vaccination drives differential mucosal neutralizing antibody profiles in naïve and SARS-CoV-2 previously-infected individuals

por Longet, Stephanie, Hargreaves, Alexander, Healy, Saoirse, Brown, Rebecca, Hornsby, Hailey R., Meardon, Naomi, Tipton, Tom, Barnes, Eleanor, Dunachie, Susanna, Duncan, Christopher J. A., Klenerman, Paul, Richter, Alex, Turtle, Lance, de Silva, Thushan I., Carroll, Miles W.
Publicado 2022

Streptococcus pyogenes Colonization in Children Aged 24–59 Months in the Gambia: Impact of Live Attenuated Influenza Vaccine and Associated Serological Responses

por Keeley, Alexander J, Groves, Danielle, Armitage, Edwin P, Senghore, Elina, Jagne, Ya Jankey, Sallah, Hadijatou J, Drammeh, Sainabou, Angyal, Adri, Hornsby, Hailey, de Crombrugghe, Gabrielle, Smeesters, Pierre R, Rossi, Omar, Carducci, Martina, Peno, Chikondi, Bogaert, Debby, Kampmann, Beate, Marks, Michael, Shaw, Helen A, Turner, Claire R, de Silva, Thushan I
Publicado 2023

Risk factors for SARS-CoV-2 seroprevalence following the first pandemic wave in UK healthcare workers in a large NHS Foundation Trust

por Hodgson, David, Colton, Hayley, Hornsby, Hailey, Brown, Rebecca, Mckenzie, Joanne, Bradley, Kirsty L., James, Cameron, Lindsey, Benjamin B., Birch, Sarah, Marsh, Louise, Wood, Steven, Bayley, Martin, Dickson, Gary, James, David C., Nicklin, Martin J.H., Sayers, Jon R., Zafred, Domen, Rowland-Jones, Sarah L., Kudesia, Goura, Kucharski, Adam, Darton, Thomas C., de Silva, Thushan I., Collini, Paul J.
Publicado 2021

Risk factors for SARS-CoV-2 seroprevalence following the first pandemic wave in UK healthcare workers in a large NHS Foundation Trust

por Colton, Hayley, Hodgson, David, Hornsby, Hailey, Brown, Rebecca, Mckenzie, Joanne, Bradley, Kirsty L., James, Cameron, Lindsey, Benjamin B., Birch, Sarah, Marsh, Louise, Wood, Steven, Bayley, Martin, Dickson, Gary, James, David C., Nicklin, Martin J., Sayers, Jon R., Zafred, Domen, Rowland-Jones, Sarah L., Kudesia, Goura, Kucharski, Adam, Darton, Thomas C., de Silva, Thushan I., Collini, Paul J.
Publicado 2022

Establishing SARS-CoV-2 membrane protein-specific antibodies as a valuable serological target via high-content microscopy

por Williams, Daniel M., Hornsby, Hailey R., Shehata, Ola M., Brown, Rebecca, Gallis, Marta, Meardon, Naomi, Newman, Thomas A.H., Plowright, Megan, Zafred, Domen, Shun-Shion, Amber S.M., Hodder, Anthony J., Bliss, Deepa, Metcalfe, Andrew, Edgar, James R., Gordon, David E., Sayers, Jon R., Nicklin, Martin J., Carroll, Miles, Collini, Paul J., Brown, Stephen, de Silva, Thushan I., Peden, Andrew A.
Publicado 2023

D614G Spike Mutation Increases SARS CoV-2 Susceptibility to Neutralization

por Weissman, Drew, Alameh, Mohamad-Gabriel, de Silva, Thushan, Collini, Paul, Hornsby, Hailey, Brown, Rebecca, LaBranche, Celia C., Edwards, Robert J., Sutherland, Laura, Santra, Sampa, Mansouri, Katayoun, Gobeil, Sophie, McDanal, Charlene, Pardi, Norbert, Hengartner, Nick, Lin, Paulo J.C., Tam, Ying, Shaw, Pamela A., Lewis, Mark G., Boesler, Carsten, Şahin, Uğur, Acharya, Priyamvada, Haynes, Barton F., Korber, Bette, Montefiori, David C.
Publicado 2021

Rapid escape of new SARS-CoV-2 Omicron variants from BA.2-directed antibody responses

por Dijokaite-Guraliuc, Aiste, Das, Raksha, Zhou, Daming, Ginn, Helen M., Liu, Chang, Duyvesteyn, Helen M.E., Huo, Jiandong, Nutalai, Rungtiwa, Supasa, Piyada, Selvaraj, Muneeswaran, de Silva, Thushan I., Plowright, Megan, Newman, Thomas A.H., Hornsby, Hailey, Mentzer, Alexander J., Skelly, Donal, Ritter, Thomas G., Temperton, Nigel, Klenerman, Paul, Barnes, Eleanor, Dunachie, Susanna J., Roemer, Cornelius, Peacock, Thomas P., Paterson, Neil G., Williams, Mark A., Hall, David R., Fry, Elizabeth E., Mongkolsapaya, Juthathip, Ren, Jingshan, Stuart, David I., Screaton, Gavin R.
Publicado 2023

Altered subgenomic RNA abundance provides unique insight into SARS-CoV-2 B.1.1.7/Alpha variant infections

por Parker, Matthew D., Stewart, Hazel, Shehata, Ola M., Lindsey, Benjamin B., Shah, Dhruv R., Hsu, Sharon, Keeley, Alexander J., Partridge, David G., Leary, Shay, Cope, Alison, State, Amy, Johnson, Katie, Ali, Nasar, Raghei, Rasha, Heffer, Joe, Smith, Nikki, Zhang, Peijun, Gallis, Marta, Louka, Stavroula F., Hornsby, Hailey R., Alamri, Hatoon, Whiteley, Max, Foulkes, Benjamin H., Christou, Stella, Wolverson, Paige, Pohare, Manoj, Hansford, Samantha E., Green, Luke R., Evans, Cariad, Raza, Mohammad, Wang, Dennis, Firth, Andrew E., Edgar, James R., Gaudieri, Silvana, Mallal, Simon, Collins, Mark O., Peden, Andrew A., de Silva, Thushan I.
Publicado 2022

A delicate balance between antibody evasion and ACE2 affinity for Omicron BA.2.75

por Huo, Jiandong, Dijokaite-Guraliuc, Aiste, Liu, Chang, Zhou, Daming, Ginn, Helen M., Das, Raksha, Supasa, Piyada, Selvaraj, Muneeswaran, Nutalai, Rungtiwa, Tuekprakhon, Aekkachai, Duyvesteyn, Helen M.E., Mentzer, Alexander J., Skelly, Donal, Ritter, Thomas G., Amini, Ali, Bibi, Sagida, Adele, Sandra, Johnson, Sile Ann, Paterson, Neil G., Williams, Mark A., Hall, David R., Plowright, Megan, Newman, Thomas A.H., Hornsby, Hailey, de Silva, Thushan I., Temperton, Nigel, Klenerman, Paul, Barnes, Eleanor, Dunachie, Susanna J., Pollard, Andrew J., Lambe, Teresa, Goulder, Philip, Fry, Elizabeth E., Mongkolsapaya, Juthathip, Ren, Jingshan, Stuart, David I., Screaton, Gavin R.
Publicado 2023

Omicron infection following vaccination enhances a broad spectrum of immune responses dependent on infection history

por Hornsby, Hailey, Nicols, Alexander R., Longet, Stephanie, Liu, Chang, Tomic, Adriana, Angyal, Adrienn, Kronsteiner, Barbara, Tyerman, Jessica K., Tipton, Tom, Zhang, Peijun, Gallis, Marta, Supasa, Piyada, Selvaraj, Muneeswaran, Abraham, Priyanka, Neale, Isabel, Ali, Mohammad, Barratt, Natalie A., Nell, Jeremy M., Gustafsson, Lotta, Strickland, Scarlett, Grouneva, Irina, Rostron, Timothy, Moore, Shona C., Hering, Luisa M., Dobson, Susan L., Bibi, Sagida, Mongkolsapaya, Juthathip, Lambe, Teresa, Wootton, Dan, Hall, Victoria, Hopkins, Susan, Dong, Tao, Barnes, Eleanor, Screaton, Gavin, Richter, Alex, Turtle, Lance, Rowland-Jones, Sarah L., Carroll, Miles, Duncan, Christopher J. A., Klenerman, Paul, Dunachie, Susanna J., Payne, Rebecca P., de Silva, Thushan I.
Publicado 2023

T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre prospective cohort study

por Angyal, Adrienn, Longet, Stephanie, Moore, Shona C, Payne, Rebecca P, Harding, Adam, Tipton, Tom, Rongkard, Patpong, Ali, Mohammad, Hering, Luisa M, Meardon, Naomi, Austin, James, Brown, Rebecca, Skelly, Donal, Gillson, Natalie, Dobson, Sue L, Cross, Andrew, Sandhar, Gurjinder, Kilby, Jonathan A, Tyerman, Jessica K, Nicols, Alexander R, Spegarova, Jarmila S, Mehta, Hema, Hornsby, Hailey, Whitham, Rachel, Conlon, Christopher P, Jeffery, Katie, Goulder, Philip, Frater, John, Dold, Christina, Pace, Matthew, Ogbe, Ane, Brown, Helen, Ansari, M Azim, Adland, Emily, Brown, Anthony, Chand, Meera, Shields, Adrian, Matthews, Philippa C, Hopkins, Susan, Hall, Victoria, James, William, Rowland-Jones, Sarah L, Klenerman, Paul, Dunachie, Susanna, Richter, Alex, Duncan, Christopher J A, Barnes, Eleanor, Carroll, Miles, Turtle, Lance, de Silva, Thushan I
Publicado 2022

Immunogenicity of standard and extended dosing intervals of BNT162b2 mRNA vaccine

por Payne, Rebecca P., Longet, Stephanie, Austin, James A., Skelly, Donal T., Dejnirattisai, Wanwisa, Adele, Sandra, Meardon, Naomi, Faustini, Sian, Al-Taei, Saly, Moore, Shona C., Tipton, Tom, Hering, Luisa M., Angyal, Adrienn, Brown, Rebecca, Nicols, Alexander R., Gillson, Natalie, Dobson, Susan L., Amini, Ali, Supasa, Piyada, Cross, Andrew, Bridges-Webb, Alice, Reyes, Laura Silva, Linder, Aline, Sandhar, Gurjinder, Kilby, Jonathan A., Tyerman, Jessica K., Altmann, Thomas, Hornsby, Hailey, Whitham, Rachel, Phillips, Eloise, Malone, Tom, Hargreaves, Alexander, Shields, Adrian, Saei, Ayoub, Foulkes, Sarah, Stafford, Lizzie, Johnson, Sile, Wootton, Daniel G., Conlon, Christopher P., Jeffery, Katie, Matthews, Philippa C., Frater, John, Deeks, Alexandra S., Pollard, Andrew J., Brown, Anthony, Rowland-Jones, Sarah L., Mongkolsapaya, Juthathip, Barnes, Eleanor, Hopkins, Susan, Hall, Victoria, Dold, Christina, Duncan, Christopher J.A., Richter, Alex, Carroll, Miles, Screaton, Gavin, de Silva, Thushan I., Turtle, Lance, Klenerman, Paul, Dunachie, Susanna
Publicado 2021

Evolution of long-term vaccine-induced and hybrid immunity in healthcare workers after different COVID-19 vaccine regimens

por Moore, Shona C., Kronsteiner, Barbara, Longet, Stephanie, Adele, Sandra, Deeks, Alexandra S., Liu, Chang, Dejnirattisai, Wanwisa, Reyes, Laura Silva, Meardon, Naomi, Faustini, Sian, Al-Taei, Saly, Tipton, Tom, Hering, Luisa M., Angyal, Adrienn, Brown, Rebecca, Nicols, Alexander R., Dobson, Susan L., Supasa, Piyada, Tuekprakhon, Aekkachai, Cross, Andrew, Tyerman, Jessica K., Hornsby, Hailey, Grouneva, Irina, Plowright, Megan, Zhang, Peijun, Newman, Thomas A.H., Nell, Jeremy M., Abraham, Priyanka, Ali, Mohammad, Malone, Tom, Neale, Isabel, Phillips, Eloise, Wilson, Joseph D., Murray, Sam M., Zewdie, Martha, Shields, Adrian, Horner, Emily C., Booth, Lucy H., Stafford, Lizzie, Bibi, Sagida, Wootton, Daniel G., Mentzer, Alexander J., Conlon, Christopher P., Jeffery, Katie, Matthews, Philippa C., Pollard, Andrew J., Brown, Anthony, Rowland-Jones, Sarah L., Mongkolsapaya, Juthathip, Payne, Rebecca P., Dold, Christina, Lambe, Teresa, Thaventhiran, James E.D., Screaton, Gavin, Barnes, Eleanor, Hopkins, Susan, Hall, Victoria, Duncan, Christopher J.A., Richter, Alex, Carroll, Miles, de Silva, Thushan I., Klenerman, Paul, Dunachie, Susanna, Turtle, Lance
Publicado 2023