Architecturally diverse proteins converge on an analogous mechanism to inactivate Uracil-DNA glycosylase

por Cole, Ambrose R., Ofer, Sapir, Ryzhenkova, Ksenia, Baltulionis, Gediminas, Hornyak, Peter, Savva, Renos
Publicado 2013

14-3-3 Activated Bacterial Exotoxins AexT and ExoT Share Actin and the SH2 Domains of CRK Proteins as Targets for ADP-Ribosylation

por Ebenwaldner, Carmen, Hornyak, Peter, García-Saura, Antonio Ginés, Torretta, Archimede, Anoosheh, Saber, Hofer, Anders, Schüler, Herwig
Publicado 2022

The XRCC1 phosphate-binding pocket binds poly (ADP-ribose) and is required for XRCC1 function

por Breslin, Claire, Hornyak, Peter, Ridley, Andrew, Rulten, Stuart L., Hanzlikova, Hana, Oliver, Antony W., Caldecott, Keith W.
Publicado 2015

Efficient Single-Strand Break Repair Requires Binding to Both Poly(ADP-Ribose) and DNA by the Central BRCT Domain of XRCC1

por Polo, Luis M., Xu, Yingqi, Hornyak, Peter, Garces, Fernando, Zeng, Zhihong, Hailstone, Richard, Matthews, Steve J., Caldecott, Keith W., Oliver, Antony W., Pearl, Laurence H.
Publicado 2019

Chlorotoxin binds to both matrix metalloproteinase 2 and neuropilin 1

por Farkas, Sándor, Cioca, Daniel, Murányi, József, Hornyák, Péter, Brunyánszki, Attila, Szekér, Patrik, Boros, Eszter, Horváth, Patrik, Hujber, Zoltán, Rácz, Gábor Z., Nagy, Noémi, Tóth, Rebeka, Nyitray, László, Péterfi, Zalán
Publicado 2023

XRCC1 Mutation is Associated with PARP1 Hyperactivation and Cerebellar Ataxia

por Hoch, Nicolas, Hanzlikova, Hana, Rulten, Stuart L., Tétreault, Martine, Koumulainen, Emilia, Ju, Limei, Hornyak, Peter, Zeng, Zhihong, Gittens, William, Rey, Stephanie, Staras, Kevin, Mancini, Grazia M.S., McKinnon, Peter J., Wang, Zhao-Qi, Wagner, Justin, Yoon, Grace, Caldecott, Keith W.
Publicado 2016

14-3-3 proteins activate Pseudomonas exotoxins-S and -T by chaperoning a hydrophobic surface

por Karlberg, Tobias, Hornyak, Peter, Pinto, Ana Filipa, Milanova, Stefina, Ebrahimi, Mahsa, Lindberg, Mikael, Püllen, Nikolai, Nordström, Axel, Löverli, Elinor, Caraballo, Rémi, Wong, Emily V., Näreoja, Katja, Thorsell, Ann-Gerd, Elofsson, Mikael, De La Cruz, Enrique M., Björkegren, Camilla, Schüler, Herwig
Publicado 2018

Mode of action of DNA-competitive small molecule inhibitors of tyrosyl DNA phosphodiesterase 2

por Hornyak, Peter, Askwith, Trevor, Walker, Sarah, Komulainen, Emilia, Paradowski, Michael, Pennicott, Lewis E., Bartlett, Edward J., Brissett, Nigel C., Raoof, Ali, Watson, Mandy, Jordan, Allan M., Ogilvie, Donald J., Ward, Simon E., Atack, John R., Pearl, Laurence H., Caldecott, Keith W., Oliver, Antony W.
Publicado 2016