Replication Study: The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

por Horrigan, Stephen K
Publicado 2017

Replication Study: Melanoma genome sequencing reveals frequent PREX2 mutations

por Horrigan, Stephen K, Courville, Pascal, Sampey, Darryl, Zhou, Faren, Cai, Steve
Publicado 2017

Comparative Pharmacokinetics of a Dual Inhibitor of HIV-1, NBD-14189, in Rats and Dogs with a Proof-of-Concept Evaluation of Antiviral Potency in SCID-hu Mouse Model

por Stoddart, Cheryl A., Curreli, Francesca, Horrigan, Stephen, Altieri, Andrea, Kurkin, Alexander V., Debnath, Asim K.
Publicado 2022

P1241: A NOVEL CEREBLON-BINDING MOLECULAR GLUE, SP-3164, SHOWS PRECLINICAL ACTIVITY IN NON-HODGKIN LYMPHOMAS

por Santiesteban, Daniela, Duncan, Aundrietta D., Mirza, Nadeem Q., Horrigan, Stephen, Dewitt, Sheila, Jacques, Vincent, Iyer, Swaminathan P.
Publicado 2023

The nicotine-degrading enzyme NicA2 reduces nicotine levels in blood, nicotine distribution to brain, and nicotine discrimination and reinforcement in rats

por Pentel, Paul R., Raleigh, Michael D., LeSage, Mark G., Thisted, Thomas, Horrigan, Stephen, Biesova, Zuzana, Kalnik, Matthew W.
Publicado 2018

Combination of Histone Deacetylase Inhibitor Panobinostat (LBH589) with β-Catenin Inhibitor Tegavivint (BC2059) Exerts Significant Anti-Myeloma Activity Both In Vitro and In Vivo

por Savvidou, Ioanna, Khong, Tiffany, Whish, Sophie, Carmichael, Irena, Sepehrizadeh, Tara, Mithraprabhu, Sridurga, Horrigan, Stephen K., de Veer, Michael, Spencer, Andrew
Publicado 2022

Pre-clinical efficacy of combined therapy with novel β-catenin antagonist BC2059 and histone deacetylase inhibitor against AML cells

por Fiskus, Warren, Sharma, Sunil, Saha, Saikat, Shah, Bhavin, Devaraj, Santhana G. T., Sun, Baohua, Horrigan, Stephen, Leveque, Christopher, Zu, Youli, Iyer, Swaminathan, Bhalla, Kapil N.
Publicado 2014

Optimization of a nicotine degrading enzyme for potential use in treatment of nicotine addiction

por Thisted, Thomas, Biesova, Zuzana, Walmacq, Celine, Stone, Everett, Rodnick-Smith, Max, Ahmed, Shaheda S., Horrigan, Stephen K., Van Engelen, Bo, Reed, Charles, Kalnik, Matthew W.
Publicado 2019

Attenuating nicotine’s effects with high affinity human anti-nicotine monoclonal antibodies

por Raleigh, Michael D., Beltraminelli, Nicola, Fallot, Stephanie, LeSage, Mark G., Saykao, Amy, Pentel, Paul R., Fuller, Steve, Thisted, Thomas, Biesova, Zuzanna, Horrigan, Stephen, Sampey, Darryl, Zhou, Bin, Kalnik, Matthew W.
Publicado 2021

Preclinical efficacy of the Wnt/β-catenin pathway inhibitor BC2059 for the treatment of desmoid tumors

por Braggio, Danielle Almeida, Costas C. de Faria, Fernanda, Koller, David, Jin, Feng, Zewdu, Abeba, Lopez, Gonzalo, Batte, Kara, Casadei, Lucia, Welliver, Meng, Horrigan, Stephen K., Han, Ruolan, Larson, Jeffrey L., Strohecker, Anne M., Pollock, Raphael E.
Publicado 2022