The Anti-Cancer IgM Monoclonal Antibody PAT-SM6 Binds with High Avidity to the Unfolded Protein Response Regulator GRP78

por Rosenes, Zachary, Mulhern, Terrence D., Hatters, Danny M., Ilag, Leodevico L., Power, Barbara E., Hosking, Chris, Hensel, Frank, Howlett, Geoffrey J., Mok, Yee-Foong
Publicado 2012

Half-life extension and non-human primate pharmacokinetic safety studies of i-body AD-114 targeting human CXCR4

por Griffiths, Katherine, Binder, Uli, McDowell, William, Tommasi, Rita, Frigerio, Mark, Darby, William G., Hosking, Chris G., Renaud, Lionel, Machacek, Matthias, Lloyd, Peter, Skerra, Arne, Foley, Michael
Publicado 2019

A single-domain i-body, AD-114, attenuates renal fibrosis through blockade of CXCR4

por Cao, Qinghua, Huang, Chunling, Yi, Hao, Gill, Anthony J., Chou, Angela, Foley, Michael, Hosking, Chris G., Lim, Kevin K., Triffon, Cristina F., Shi, Ying, Chen, Xin-Ming, Pollock, Carol A.
Publicado 2022