Prolonged inhibition of 5-HT(3) receptors by palonosetron results from surface receptor inhibition rather than inducing receptor internalization

por Hothersall, J Daniel, Moffat, Christopher, Connolly, Christopher N
Publicado 2013

5-Hydroxytryptamine (5-HT) Cellular Sequestration during Chronic Exposure Delays 5-HT(3) Receptor Resensitization due to Its Subsequent Release

por Hothersall, J. Daniel, Alexander, Amy, Samson, Andrew J., Moffat, Christopher, Bollan, Karen A., Connolly, Christopher N.
Publicado 2014

High-affinity fluorescent ligands for the 5-HT(3) receptor

por Simonin, Jonathan, Vernekar, Sanjeev Kumar V., Thompson, Andrew J., Hothersall, J. Daniel, Connolly, Christopher N., Lummis, Sarah C.R., Lochner, Martin
Publicado 2012

Structure-Activity Relationships of the Sustained Effects of Adenosine A2A Receptor Agonists Driven by Slow Dissociation Kinetics

por Hothersall, J. Daniel, Guo, Dong, Sarda, Sunil, Sheppard, Robert J., Chen, Hongming, Keur, Wesley, Waring, Michael J., IJzerman, Adriaan P., Hill, Stephen J., Dale, Ian L., Rawlins, Philip B.
Publicado 2017

Supramolecular self-associating amphiphiles (SSAs) as nanoscale enhancers of cisplatin anticancer activity

por Dora, Nova O., Blackburn, Edith, Boles, Jessica E., Williams, George T., White, Lisa J., Turner, Scarlett E. G., Hothersall, J. Daniel, Askwith, Trevor, Doolan, Jack A., Mulvihill, Daniel P., Garrett, Michelle D., Hiscock, Jennifer R.
Publicado 2021