Closely related type II-C Cas9 orthologs recognize diverse PAMs

por Wei, Jingjing, Hou, Linghui, Liu, Jingtong, Wang, Ziwen, Gao, Siqi, Qi, Tao, Gao, Song, Sun, Shuna, Wang, Yongming
Publicado 2022

Identification of SaCas9 orthologs containing a conserved serine residue that determines simple NNGG PAM recognition

por Wang, Shuai, Tao, Chen, Mao, Huilin, Hou, Linghui, Wang, Yao, Qi, Tao, Yang, Yuan, Ong, Sang-Ging, Hu, Shijun, Chai, Renjie, Wang, Yongming
Publicado 2022

Prediction of base editor off-targets by deep learning

por Zhang, Chengdong, Yang, Yuan, Qi, Tao, Zhang, Yuening, Hou, Linghui, Wei, Jingjing, Yang, Jingcheng, Shi, Leming, Ong, Sang-Ging, Wang, Hongyan, Wang, Hui, Yu, Bo, Wang, Yongming
Publicado 2023

Compact SchCas9 Recognizes the Simple NNGR PAM

por Wang, Shuai, Mao, Huilin, Hou, Linghui, Hu, Ziying, Wang, Yao, Qi, Tao, Tao, Chen, Yang, Yuan, Zhang, Chengdong, Li, Miaomiao, Liu, Huihui, Hu, Shijun, Chai, Renjie, Wang, Yongming
Publicado 2021

Discovery and engineering of small SlugCas9 with broad targeting range and high specificity and activity

por Hu, Ziying, Zhang, Chengdong, Wang, Shuai, Gao, Siqi, Wei, Jingjing, Li, Miaomiao, Hou, Linghui, Mao, Huilin, Wei, Yanyan, Qi, Tao, Liu, Hongmao, Liu, Dong, Lan, Feng, Lu, Daru, Wang, Hongyan, Li, Jixi, Wang, Yongming
Publicado 2021