Choosing the optimal spectroscopic toolkit to understand protein function

por Hough, Michael A.
Publicado 2017

From crystal to structure with CCP4

por Hough, Michael A., Wilson, Keith S.
Publicado 2018

Serial synchrotron and XFEL crystallography for studies of metalloprotein catalysis

por Hough, Michael A., Owen, Robin L.
Publicado 2021

Perspective: Structure determination of protein-ligand complexes at room temperature using X-ray diffraction approaches

por Hough, Michael A., Prischi, Filippo, Worrall, Jonathan A. R.
Publicado 2023

Structural Evidence for a Copper-Bound Carbonate Intermediate in the Peroxidase and Dismutase Activities of Superoxide Dismutase

por Strange, Richard W., Hough, Michael A., Antonyuk, Svetlana V., Hasnain, S. Samar
Publicado 2012

Challenges and solutions for the analysis of in situ, in crystallo micro-spectrophotometric data

por Dworkowski, Florian S. N., Hough, Michael A., Pompidor, Guillaume, Fuchs, Martin R.
Publicado 2015

A QM/MM Study of Nitrite Binding Modes in a Three-Domain Heme-Cu Nitrite Reductase

por Sen, Kakali, Hough, Michael A., Strange, Richard W., Yong, Chin W., Keal, Thomas W.
Publicado 2018

New insights into controlling radical migration pathways in heme enzymes gained from the study of a dye-decolorising peroxidase

por Lučić, Marina, Wilson, Michael T., Pullin, Jacob, Hough, Michael A., Svistunenko, Dimitri A., Worrall, Jonathan A. R.
Publicado 2023

Serial crystallography captures enzyme catalysis in copper nitrite reductase at atomic resolution from one crystal

por Horrell, Sam, Antonyuk, Svetlana V., Eady, Robert R., Hasnain, S. Samar, Hough, Michael A., Strange, Richard W.
Publicado 2016

Aspartate or arginine? Validated redox state X-ray structures elucidate mechanistic subtleties of Fe(IV) = O formation in bacterial dye-decolorizing peroxidases

por Lučić, Marina, Wilson, Michael T., Svistunenko, Dimitri A., Owen, Robin L., Hough, Michael A., Worrall, Jonathan A. R.
Publicado 2021

Nature of the copper-nitrosyl intermediates of copper nitrite reductases during catalysis

por Hough, Michael A., Conradie, Jeanet, Strange, Richard W., Antonyuk, Svetlana V., Eady, Robert R., Ghosh, Abhik, Hasnain, S. Samar
Publicado 2020

Modulation of ligand–heme reactivity by binding pocket residues demonstrated in cytochrome c' over the femtosecond–second temporal range

por Russell, Henry J., Hardman, Samantha J. O., Heyes, Derren J., Hough, Michael A., Greetham, Gregory M., Towrie, Michael, Hay, Sam, Scrutton, Nigel S.
Publicado 2013

Serial Femtosecond Crystallography Reveals the Role of Water in the One- or Two-Electron Redox Chemistry of Compound I in the Catalytic Cycle of the B-Type Dye-Decolorizing Peroxid...

por Lučić, Marina, Wilson, Michael T., Tosha, Takehiko, Sugimoto, Hiroshi, Shilova, Anastasya, Axford, Danny, Owen, Robin L., Hough, Michael A., Worrall, Jonathan A. R.
Publicado 2022

Photoreduction and validation of haem–ligand intermediate states in protein crystals by in situ single-crystal spectroscopy and diffraction

por Kekilli, Demet, Moreno-Chicano, Tadeo, Chaplin, Amanda K., Horrell, Sam, Dworkowski, Florian S. N., Worrall, Jonathan A. R., Strange, Richard W., Hough, Michael A.
Publicado 2017

Resolving polymorphs and radiation-driven effects in microcrystals using fixed-target serial synchrotron crystallography

por Ebrahim, Ali, Appleby, Martin V., Axford, Danny, Beale, John, Moreno-Chicano, Tadeo, Sherrell, Darren A., Strange, Richard W., Hough, Michael A., Owen, Robin L.
Publicado 2018

One fold, two functions: cytochrome P460 and cytochrome c′-β from the methanotroph Methylococcus capsulatus (Bath)

por Adams, Hannah R., Krewson, Callie, Vardanega, Jenny E., Fujii, Sotaro, Moreno, Tadeo, Chicano, Sambongi, Yoshihiro, Svistunenko, Dimitri, Paps, Jordi, Andrew, Colin R., Hough, Michael A.
Publicado 2019

Correction: One fold, two functions: cytochrome P460 and cytochrome c′-β from the methanotroph Methylococcus capsulatus (Bath)

por Adams, Hannah R., Krewson, Callie, Vardanega, Jenny E., Fujii, Sotaro, Moreno-Chicano, Tadeo, Sambongi, Yoshihiro, Svistunenko, Dimitri, Paps, Jordi, Andrew, Colin R., Hough, Michael A.
Publicado 2019

Correction: One fold, two functions: cytochrome P460 and cytochrome c′-β from the methanotroph Methylococcus capsulatus (Bath)

por Adams, Hannah R., Krewson, Callie, Vardanega, Jenny E., Fujii, Sotaro, Moreno-Chicano, Tadeo, Sambongi, Yoshihiro, Svistunenko, Dimitri, Paps, Jordi, Andrew, Colin R., Hough, Michael A.
Publicado 2019

Active-site protein dynamics and solvent accessibility in native Achromobacter cycloclastes copper nitrite reductase

por Sen, Kakali, Horrell, Sam, Kekilli, Demet, Yong, Chin W., Keal, Thomas W., Atakisi, Hakan, Moreau, David W., Thorne, Robert E., Hough, Michael A., Strange, Richard W.
Publicado 2017

Differential protein expression during growth on model and commercial mixtures of naphthenic acids in Pseudomonas fluorescens Pf‐5

por McKew, Boyd A., Johnson, Richard, Clothier, Lindsay, Skeels, Karl, Ross, Matthew S., Metodiev, Metodi, Frenzel, Max, Gieg, Lisa M., Martin, Jonathan W., Hough, Michael A., Whitby, Corinne
Publicado 2021