A Mouse Model for Osseous Heteroplasia

por Cheeseman, Michael T., Vowell, Kate, Hough, Tertius A., Jones, Lynn, Pathak, Paras, Tyrer, Hayley E., Kelly, Michelle, Cox, Roger, Warren, Madhuri V., Peters, Jo
Publicado 2012

A mouse model for inherited renal fibrosis associated with endoplasmic reticulum stress

por Piret, Sian E., Olinger, Eric, Reed, Anita A. C., Nesbit, M. Andrew, Hough, Tertius A., Bentley, Liz, Devuyst, Olivier, Cox, Roger D., Thakker, Rajesh V.
Publicado 2017

N‐ethyl‐N‐nitrosourea–Induced Adaptor Protein 2 Sigma Subunit 1 (Ap2s1) Mutations Establish Ap2s1 Loss‐of‐Function Mice

por Gorvin, Caroline M, Rogers, Angela, Stewart, Michelle, Paudyal, Anju, Hough, Tertius A, Teboul, Lydia, Wells, Sara, Brown, Steve DM, Cox, Roger D, Thakker, Rajesh V
Publicado 2017

Loss of arylformamidase with reduced thymidine kinase expression leads to impaired glucose tolerance

por Hugill, Alison J., Stewart, Michelle E., Yon, Marianne A., Probert, Fay, Cox, I. Jane, Hough, Tertius A., Scudamore, Cheryl L., Bentley, Liz, Wall, Gary, Wells, Sara E., Cox, Roger D.
Publicado 2015

Next-generation sequencing to dissect hereditary nephrotic syndrome in mice identifies a hypomorphic mutation in Lamb2 and models Pierson’s syndrome

por Bull, Katherine R, Mason, Thomas, Rimmer, Andrew J, Crockford, Tanya L, Silver, Karlee L, Bouriez-Jones, Tiphaine, Hough, Tertius A, Chaudhry, Shirine, Roberts, Ian SD, Goodnow, Christopher C, Cornall, Richard J
Publicado 2013

The Calcilytic Agent NPS 2143 Rectifies Hypocalcemia in a Mouse Model With an Activating Calcium-Sensing Receptor (CaSR) Mutation: Relevance to Autosomal Dominant Hypocalcemia Type...

por Hannan, Fadil M., Walls, Gerard V., Babinsky, Valerie N., Nesbit, M. Andrew, Kallay, Enikö, Hough, Tertius A., Fraser, William D., Cox, Roger D., Hu, Jianxin, Spiegel, Allen M., Thakker, Rajesh V.
Publicado 2015

Cinacalcet corrects hypercalcemia in mice with an inactivating Gα(11) mutation

por Howles, Sarah A., Hannan, Fadil M., Gorvin, Caroline M., Piret, Sian E., Paudyal, Anju, Stewart, Michelle, Hough, Tertius A., Nesbit, M. Andrew, Wells, Sara, Brown, Stephen D.M., Cox, Roger D., Thakker, Rajesh V.
Publicado 2017

Pharmacological Inhibition of FTO

por McMurray, Fiona, Demetriades, Marina, Aik, WeiShen, Merkestein, Myrte, Kramer, Holger, Andrew, Daniel S., Scudamore, Cheryl L., Hough, Tertius A., Wells, Sara, Ashcroft, Frances M., McDonough, Michael A., Schofield, Christopher J., Cox, Roger D.
Publicado 2015

HIF–VEGF Pathways Are Critical for Chronic Otitis Media in Junbo and Jeff Mouse Mutants

por Cheeseman, Michael T., Tyrer, Hayley E., Williams, Debbie, Hough, Tertius A., Pathak, Paras, Romero, Maria R., Hilton, Helen, Bali, Sulzhan, Parker, Andrew, Vizor, Lucie, Purnell, Tom, Vowell, Kate, Wells, Sara, Bhutta, Mahmood F., Potter, Paul K., Brown, Steve D. M.
Publicado 2011

A Mouse with an N-Ethyl-N-Nitrosourea (ENU) Induced Trp589Arg Galnt3 Mutation Represents a Model for Hyperphosphataemic Familial Tumoural Calcinosis

por Esapa, Christopher T., Head, Rosie A., Jeyabalan, Jeshmi, Evans, Holly, Hough, Tertius A., Cheeseman, Michael T., McNally, Eugene G., Carr, Andrew J., Thomas, Gethin P., Brown, Matthew A., Croucher, Peter I., Brown, Steve D. M., Cox, Roger D., Thakker, Rajesh V.
Publicado 2012

Mutation at the Evi1 Locus in Junbo Mice Causes Susceptibility to Otitis Media

por Parkinson, Nicholas, Hardisty-Hughes, Rachel E, Tateossian, Hilda, Tsai, Hsun-Tien, Brooker, Debra, Morse, Sue, Lalane, Zuzanna, MacKenzie, Francesca, Fray, Martin, Glenister, Pete, Woodward, Anne-Marie, Polley, Sian, Barbaric, Ivana, Dear, Neil, Hough, Tertius A, Hunter, A. Jackie, Cheeseman, Michael T, Brown, Steve D. M
Publicado 2006

An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess

por Bentley, Liz, Esapa, Christopher T., Nesbit, M. Andrew, Head, Rosie A., Evans, Holly, Lath, Darren, Scudamore, Cheryl L., Hough, Tertius A., Podrini, Christine, Hannan, Fadil M., Fraser, William D., Croucher, Peter I., Brown, Matthew A., Brown, Steve D. M., Cox, Roger D., Thakker, Rajesh V.
Publicado 2014

Gα(11) mutation in mice causes hypocalcemia rectifiable by calcilytic therapy

por Gorvin, Caroline M., Hannan, Fadil M., Howles, Sarah A., Babinsky, Valerie N., Piret, Sian E., Rogers, Angela, Freidin, Andrew J., Stewart, Michelle, Paudyal, Anju, Hough, Tertius A., Nesbit, M. Andrew, Wells, Sara, Vincent, Tonia L., Brown, Stephen D.M., Cox, Roger D., Thakker, Rajesh V.
Publicado 2017

Mutant Mice With Calcium-Sensing Receptor Activation Have Hyperglycemia That Is Rectified by Calcilytic Therapy

por Babinsky, Valerie N., Hannan, Fadil M., Ramracheya, Reshma D., Zhang, Quan, Nesbit, M. Andrew, Hugill, Alison, Bentley, Liz, Hough, Tertius A., Joynson, Elizabeth, Stewart, Michelle, Aggarwal, Abhishek, Prinz-Wohlgenannt, Maximilian, Gorvin, Caroline M., Kallay, Enikö, Wells, Sara, Cox, Roger D., Richards, Duncan, Rorsman, Patrik, Thakker, Rajesh V.
Publicado 2017

Autosomal Dominant Hypercalciuria in a Mouse Model Due to a Mutation of the Epithelial Calcium Channel, TRPV5

por Loh, Nellie Y., Bentley, Liz, Dimke, Henrik, Verkaart, Sjoerd, Tammaro, Paolo, Gorvin, Caroline M., Stechman, Michael J., Ahmad, Bushra N., Hannan, Fadil M., Piret, Sian E., Evans, Holly, Bellantuono, Ilaria, Hough, Tertius A., Fraser, William D., Hoenderop, Joost G. J., Ashcroft, Frances M., Brown, Steve D. M., Bindels, René J. M., Cox, Roger D., Thakker, Rajesh V.
Publicado 2013

An N‐Ethyl‐N‐Nitrosourea (ENU)‐Induced Tyr265Stop Mutation of the DNA Polymerase Accessory Subunit Gamma 2 (Polg2) Is Associated With Renal Calcification in Mice

por Gorvin, Caroline M, Ahmad, Bushra N, Stechman, Michael J, Loh, Nellie Y, Hough, Tertius A, Leo, Paul, Marshall, Mhairi, Sethi, Siddharth, Bentley, Liz, Piret, Sian E, Reed, Anita, Jeyabalan, Jeshmi, Christie, Paul T, Wells, Sara, Simon, Michelle M, Mallon, Ann‐Marie, Schulz, Herbert, Huebner, Norbert, Brown, Matthew A, Cox, Roger D, Brown, Steve D, Thakker, Rajesh V
Publicado 2018

Chronically elevated branched chain amino acid levels are pro-arrhythmic

por Portero, Vincent, Nicol, Thomas, Podliesna, Svitlana, Marchal, Gerard A, Baartscheer, Antonius, Casini, Simona, Tadros, Rafik, Treur, Jorien L, Tanck, Michael W T, Cox, I Jane, Probert, Fay, Hough, Tertius A, Falcone, Sara, Beekman, Leander, Müller-Nurasyid, Martina, Kastenmüller, Gabi, Gieger, Christian, Peters, Annette, Kääb, Stefan, Sinner, Moritz F, Blease, Andrew, Verkerk, Arie O, Bezzina, Connie R, Potter, Paul K, Remme, Carol Ann
Publicado 2021

A Mouse Model with a Frameshift Mutation in the Nuclear Factor I/X ( NFIX ) Gene Has Phenotypic Features of Marshall‐Smith Syndrome

por Kooblall, Kreepa G., Stevenson, Mark, Stewart, Michelle, Harris, Lachlan, Zalucki, Oressia, Dewhurst, Hannah, Butterfield, Natalie, Leng, Houfu, Hough, Tertius A., Ma, Da, Siow, Bernard, Potter, Paul, Cox, Roger D., Brown, Stephen D.M., Horwood, Nicole, Wright, Benjamin, Lockstone, Helen, Buck, David, Vincent, Tonia L., Hannan, Fadil M., Bassett, J.H. Duncan, Williams, Graham R., Lines, Kate E., Piper, Michael, Wells, Sara, Teboul, Lydia, Hennekam, Raoul C., Thakker, Rajesh V.
Publicado 2023

Mice with a Brd4 Mutation Represent a New Model of Nephrocalcinosis

por Gorvin, Caroline M, Loh, Nellie Y, Stechman, Michael J, Falcone, Sara, Hannan, Fadil M, Ahmad, Bushra N, Piret, Sian E, Reed, Anita AC, Jeyabalan, Jeshmi, Leo, Paul, Marshall, Mhairi, Sethi, Siddharth, Bass, Paul, Roberts, Ian, Sanderson, Jeremy, Wells, Sara, Hough, Tertius A, Bentley, Liz, Christie, Paul T, Simon, Michelle M, Mallon, Ann‐Marie, Schulz, Herbert, Cox, Roger D, Brown, Matthew A, Huebner, Norbert, Brown, Steve D, Thakker, Rajesh V
Publicado 2019

A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes

por Peiris, Heshan, Duffield, Michael D., Fadista, Joao, Jessup, Claire F., Kashmir, Vinder, Genders, Amanda J., McGee, Sean L., Martin, Alyce M., Saiedi, Madiha, Morton, Nicholas, Carter, Roderick, Cousin, Michael A., Kokotos, Alexandros C., Oskolkov, Nikolay, Volkov, Petr, Hough, Tertius A., Fisher, Elizabeth M. C., Tybulewicz, Victor L. J., Busciglio, Jorge, Coskun, Pinar E., Becker, Ann, Belichenko, Pavel V., Mobley, William C., Ryan, Michael T., Chan, Jeng Yie, Laybutt, D. Ross, Coates, P. Toby, Yang, Sijun, Ling, Charlotte, Groop, Leif, Pritchard, Melanie A., Keating, Damien J.
Publicado 2016