Pharmacological validation of a novel nonhuman primate measure of thermal responsivity with utility for predicting analgesic effects

por Vardigan, Joshua D, Houghton, Andrea K, Lange, Henry S, Adarayan, Emily D, Pall, Parul S, Ballard, Jeanine E, Henze, Darrell A, Uslaner, Jason M
Publicado 2018

fMRI study of the role of glutamate NMDA receptor in the olfactory processing in monkeys

por Zhao, Fuqiang, Holahan, Marie A., Wang, Xiaohai, Uslaner, Jason M., Houghton, Andrea K., Evelhoch, Jeffrey L., Winkelmann, Christopher T., Hines, Catherine D. G.
Publicado 2018

Application of Pharmacokinetic-Pharmacodynamic Modeling to Inform Translation of In Vitro NaV1.7 Inhibition to In Vivo Pharmacological Response in Non-human Primate

por Ballard, Jeanine E., Pall, Parul, Vardigan, Joshua, Zhao, Fuqiang, Holahan, Marie A., Kraus, Richard, Li, Yuxing, Henze, Darrell, Houghton, Andrea, Burgey, Christopher S., Gibson, Christopher
Publicado 2020

Bilateral Sensory Abnormalities in Patients with Unilateral Neuropathic Pain; A Quantitative Sensory Testing (QST) Study

por Konopka, Karl-Heinz, Harbers, Marten, Houghton, Andrea, Kortekaas, Rudie, van Vliet, Andre, Timmerman, Wia, den Boer, Johan A., Struys, Michel M.R.F., van Wijhe, Marten
Publicado 2012

Somatosensory Profiles but Not Numbers of Somatosensory Abnormalities of Neuropathic Pain Patients Correspond with Neuropathic Pain Grading

por Konopka, Karl-Heinz, Harbers, Marten, Houghton, Andrea, Kortekaas, Rudie, van Vliet, Andre, Timmerman, Wia, den Boer, Johan A., Struys, Michel M. R. F., van Wijhe, Marten
Publicado 2012

Distinct BOLD fMRI Responses of Capsaicin-Induced Thermal Sensation Reveal Pain-Related Brain Activation in Nonhuman Primates

por Asad, Abu Bakar Ali, Seah, Stephanie, Baumgartner, Richard, Feng, Dai, Jensen, Andres, Manigbas, Elaine, Henry, Brian, Houghton, Andrea, Evelhoch, Jeffrey L., Derbyshire, Stuart W. G., Chin, Chih-Liang
Publicado 2016

Translational Pharmacokinetic–Pharmacodynamic Modeling of NaV1.7 Inhibitor MK-2075 to Inform Human Efficacious Dose

por Ballard, Jeanine E., Pall, Parul S., Vardigan, Joshua, Zhao, Fuqiang, Holahan, Marie A., Zhou, Xiaoping, Jochnowitz, Nina, Kraus, Richard L., Klein, Rebecca M., Henze, Darrell A., Houghton, Andrea K., Burgey, Christopher S., Gibson, Christopher, Struyk, Arie
Publicado 2021

Association of respiratory failure with inhibition of NaV1.6 in the phrenic nerve

por Klein, Rebecca M., Layton, Mark E., Regan, Hillary, Regan, Christopher P., Li, Yuxing, Filzen, Tracey, Cato, Matt, Clements, Michelle K., Wang, Jixin, Sanoja, Raul, Greshock, Thomas J., Roecker, Anthony J., Pero, Joseph E., Kim, Ron, Burgey, Christopher, John, Christopher T., Wang, Ying-Hong, Bhandari, Neetesh, Struyk, Arie, Kraus, Richard L., Henze, Darrell A., Houghton, Andrea K.
Publicado 2022