PLATYPUS: A Multiple–View Learning Predictive Framework for Cancer Drug Sensitivity Prediction

por Graim, Kiley, Friedl, Verena, Houlahan, Kathleen E., Stuart, Joshua M.
Publicado 2019

Germline-mediated immunoediting sculpts breast cancer subtypes and metastatic proclivity

por Houlahan, Kathleen E., Khan, Aziz, Greenwald, Noah F, West, Robert B., Angelo, Michael, Curtis, Christina
Publicado 2023

Modelling the MYC-driven normal-to-tumour switch in breast cancer

por Lourenco, Corey, Kalkat, Manpreet, Houlahan, Kathleen E., De Melo, Jason, Longo, Joseph, Done, Susan J., Boutros, Paul C., Penn, Linda Z.
Publicado 2019

Copy Number Profiles of Prostate Cancer in Men of Middle Eastern Ancestry

por Albawardi, Alia, Livingstone, Julie, Almarzooqi, Saeeda, Palanisamy, Nallasivam, Houlahan, Kathleen E., Awwad, Aktham Adnan Ahmad, Abdelsalam, Ramy A., Boutros, Paul C., Bismar, Tarek A.
Publicado 2021

MYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability

por Dingar, Dharmendra, Tu, William B., Resetca, Diana, Lourenco, Corey, Tamachi, Aaliya, De Melo, Jason, Houlahan, Kathleen E., Kalkat, Manpreet, Chan, Pak-Kei, Boutros, Paul C., Raught, Brian, Penn, Linda Z.
Publicado 2018

Germline contamination and leakage in whole genome somatic single nucleotide variant detection

por Sendorek, Dorota H., Caloian, Cristian, Ellrott, Kyle, Bare, J. Christopher, Yamaguchi, Takafumi N., Ewing, Adam D., Houlahan, Kathleen E., Norman, Thea C., Margolin, Adam A., Stuart, Joshua M., Boutros, Paul C.
Publicado 2018

Prostate cancer multiparametric magnetic resonance imaging visibility is a tumor-intrinsic phenomena

por Khoo, Amanda, Liu, Lydia Y., Sadun, Taylor Y., Salmasi, Amirali, Pooli, Aydin, Felker, Ely, Houlahan, Kathleen E., Ignatchenko, Vladimir, Raman, Steven S., Sisk, Anthony E., Reiter, Robert E., Boutros, Paul C., Kislinger, Thomas
Publicado 2022

Cross-species transcriptomic analysis elucidates constitutive aryl hydrocarbon receptor activity

por Sun, Ren X, Chong, Lauren C, Simmons, Trent T, Houlahan, Kathleen E, Prokopec, Stephenie D, Watson, John D, Moffat, Ivy D, Lensu, Sanna, Lindén, Jere, P’ng, Christine, Okey, Allan B, Pohjanvirta, Raimo, Boutros, Paul C
Publicado 2014

Valection: design optimization for validation and verification studies

por Cooper, Christopher I, Yao, Delia, Sendorek, Dorota H, Yamaguchi, Takafumi N, P’ng, Christine, Houlahan, Kathleen E, Caloian, Cristian, Fraser, Michael, Ellrott, Kyle, Margolin, Adam A, Bristow, Robert G, Stuart, Joshua M, Boutros, Paul C
Publicado 2018

Deterministic evolution and stringent selection during preneoplasia

por Karlsson, Kasper, Przybilla, Moritz J., Kotler, Eran, Khan, Aziz, Xu, Hang, Karagyozova, Kremena, Sockell, Alexandra, Wong, Wing H., Liu, Katherine, Mah, Amanda, Lo, Yuan-Hung, Lu, Bingxin, Houlahan, Kathleen E., Ma, Zhicheng, Suarez, Carlos J., Barnes, Chris P., Kuo, Calvin J., Curtis, Christina
Publicado 2023

Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection

por Ewing, Adam D, Houlahan, Kathleen E, Hu, Yin, Ellrott, Kyle, Caloian, Cristian, Yamaguchi, Takafumi N, Bare, J Christopher, P’ng, Christine, Waggott, Daryl, Sabelnykova, Veronica Y, Kellen, Michael R, Norman, Thea C, Haussler, David, Friend, Stephen H, Stolovitzky, Gustavo, Margolin, Adam A, Stuart, Joshua M, Boutros, Paul C
Publicado 2015

Compendium of TCDD-mediated transcriptomic response datasets in mammalian model systems

por Prokopec, Stephenie D., Houlahan, Kathleen E., Sun, Ren X., Watson, John D., Yao, Cindy Q., Lee, Jamie, P’ng, Christine, Pang, Renee, Wu, Alexander H., Chong, Lauren C., Smith, Ashley B., Harding, Nicholas J., Moffat, Ivy D., Lindén, Jere, Lensu, Sanna, Okey, Allan B., Pohjanvirta, Raimo, Boutros, Paul C.
Publicado 2017

Combining accurate tumor genome simulation with crowdsourcing to benchmark somatic structural variant detection

por Lee, Anna Y., Ewing, Adam D., Ellrott, Kyle, Hu, Yin, Houlahan, Kathleen E., Bare, J. Christopher, Espiritu, Shadrielle Melijah G., Huang, Vincent, Dang, Kristen, Chong, Zechen, Caloian, Cristian, Yamaguchi, Takafumi N., Kellen, Michael R., Chen, Ken, Norman, Thea C., Friend, Stephen H., Guinney, Justin, Stolovitzky, Gustavo, Haussler, David, Margolin, Adam A., Stuart, Joshua M., Boutros, Paul C.
Publicado 2018

Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer

por Lee, Joyce V., Housley, Filomena, Yau, Christina, Nakagawa, Rachel, Winkler, Juliane, Anttila, Johanna M., Munne, Pauliina M., Savelius, Mariel, Houlahan, Kathleen E., Van de Mark, Daniel, Hemmati, Golzar, Hernandez, Grace A., Zhang, Yibing, Samson, Susan, Baas, Carole, Kok, Marleen, Esserman, Laura J., van ‘t Veer, Laura J., Rugo, Hope S., Curtis, Christina, Klefström, Juha, Matloubian, Mehrdad, Goga, Andrei
Publicado 2022

Author Correction: Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer

por Lee, Joyce V., Housley, Filomena, Yau, Christina, Nakagawa, Rachel, Winkler, Juliane, Anttila, Johanna M., Munne, Pauliina M., Savelius, Mariel, Houlahan, Kathleen E., Van de Mark, Daniel, Hemmati, Golzar, Hernandez, Grace A., Zhang, Yibing, Samson, Susan, Baas, Carole, Kok, Marleen, Esserman, Laura J., van ‘t Veer, Laura J., Rugo, Hope S., Curtis, Christina, Klefström, Juha, Matloubian, Mehrdad, Goga, Andrei
Publicado 2022

Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH

por Hung, King L., Luebeck, Jens, Dehkordi, Siavash R., Colón, Caterina I., Li, Rui, Wong, Ivy Tsz-Lo, Coruh, Ceyda, Dharanipragada, Prashanthi, Lomeli, Shirley H., Weiser, Natasha E., Moriceau, Gatien, Zhang, Xiao, Bailey, Chris, Houlahan, Kathleen E., Yang, Wenting, González, Rocío Chamorro, Swanton, Charles, Curtis, Christina, Jamal-Hanjani, Mariam, Henssen, Anton G., Law, Julie A., Greenleaf, William J., Lo, Roger S., Mischel, Paul S., Bafna, Vineet, Chang, Howard Y.
Publicado 2022

CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer

por Ahmed, Musaddeque, Soares, Fraser, Xia, Ji-Han, Yang, Yue, Li, Jing, Guo, Haiyang, Su, Peiran, Tian, Yijun, Lee, Hyung Joo, Wang, Miranda, Akhtar, Nayeema, Houlahan, Kathleen E., Bosch, Almudena, Zhou, Stanley, Mazrooei, Parisa, Hua, Junjie T., Chen, Sujun, Petricca, Jessica, Zeng, Yong, Davies, Alastair, Fraser, Michael, Quigley, David A., Feng, Felix Y., Boutros, Paul C., Lupien, Mathieu, Zoubeidi, Amina, Wang, Liang, Walsh, Martin J., Wang, Ting, Ren, Shancheng, Wei, Gong-Hong, He, Housheng Hansen
Publicado 2021

BPG: Seamless, automated and interactive visualization of scientific data

por P’ng, Christine, Green, Jeffrey, Chong, Lauren C., Waggott, Daryl, Prokopec, Stephenie D., Shamsi, Mehrdad, Nguyen, Francis, Mak, Denise Y. F., Lam, Felix, Albuquerque, Marco A., Wu, Ying, Jung, Esther H., Starmans, Maud H. W., Chan-Seng-Yue, Michelle A., Yao, Cindy Q., Liang, Bianca, Lalonde, Emilie, Haider, Syed, Simone, Nicole A., Sendorek, Dorota, Chu, Kenneth C., Moon, Nathalie C., Fox, Natalie S., Grzadkowski, Michal R., Harding, Nicholas J., Fung, Clement, Murdoch, Amanda R., Houlahan, Kathleen E., Wang, Jianxin, Garcia, David R., de Borja, Richard, Sun, Ren X., Lin, Xihui, Chen, Gregory M., Lu, Aileen, Shiah, Yu-Jia, Zia, Amin, Kearns, Ryan, Boutros, Paul C.
Publicado 2019

Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts

por Strand, Siri H., Rivero-Gutiérrez, Belén, Houlahan, Kathleen E., Seoane, Jose A., King, Lorraine M., Risom, Tyler, Simpson, Lunden A., Vennam, Sujay, Khan, Aziz, Cisneros, Luis, Hardman, Timothy, Harmon, Bryan, Couch, Fergus, Gallagher, Kristalyn, Kilgore, Mark, We, Shi, DeMichele, Angela, King, Tari, McAuliffe, Priscilla F., Nangia, Julie, Lee, Joanna, Tseng, Jennifer, Storniolo, Anna Maria, Thompson, Alastair M., Gupta, Gaorav P., Burns, Robyn, Veis, Deborah J., DeSchryver, Katherine, Zhu, Chunfang, Matusiak, Magdalena, Wang, Jason, Zhu, Shirley X., Tappenden, Jen, Ding, Daisy Yi, Zhang, Dadong, Luo, Jingqin, Jiang, Shu, Varma, Sushama, Anderson, Lauren, Straub, Cody, Srivastava, Sucheta, Curtis, Christina, Tibshirani, Rob, Angelo, Robert Michael, Hall, Allison, Owzar, Kouros, Polyak, Kornelia, Maley, Carlo, Marks, Jeffrey R., Colditz, Graham A., Shelley Hwang, E., West, Robert B.
Publicado 2023

DNA methylation landscapes in advanced prostate cancer

por Zhao, Shuang G., Chen, William S., Li, Haolong, Foye, Adam, Zhang, Meng, Sjöström, Martin, Aggarwal, Rahul, Playdle, Denise, Liao, Arnold, Alumkal, Joshi J., Das, Rajdeep, Chou, Jonathan, Hua, Junjie T., Barnard, Travis J., Bailey, Adina M., Chow, Eric, Perry, Marc, Dang, Ha X., Yang, Rendong, Moussavi-Baygi, Ruhollah, Zhang, Li, Alshalalfa, Mohammed, Chang, S. Laura, Houlahan, Kathleen E., Shiah, Yu-Jia, Beer, Tomasz M., Thomas, George, Chi, Kim N., Gleave, Martin, Zoubeidi, Amina, Reiter, Robert E., Rettig, Matthew B., Witte, Owen, Kim, M. Yvonne, Fong, Lawrence, Spratt, Daniel E., Morgan, Todd M, Bose, Rohit, Huang, Franklin W., Li, Hui, Chesner, Lisa, Shenoy, Tanushree, Goodarzi, Hani, Asangani, Irfan A., Sandhu, Shahneen, Lang, Joshua M., Mahajan, Nupam, Lara, Primo N., Evans, Christopher P., Febbo, Phillip, Batzoglou, Serafim, Knudsen, Karen E., He, Housheng H., Huang, Jiaoti, Zwart, Wilbert, Costello, Joseph F., Luo, Jianhua, Tomlins, Scott A., Wyatt, Alexander W., Dehm, Scott M., Ashworth, Alan, Gilbert, Luke A., Boutros, Paul C., Farh, Kyle, Chinnaiyan, Arul M., Maher, Christopher A., Small, Eric J., Quigley, David A., Feng, Felix Y.
Publicado 2020