Immunity protein release from a cell-bound nuclease colicin complex requires global conformational rearrangement

por Vankemmelbeke, Mireille, Housden, Nicholas G, James, Richard, Kleanthous, Colin, Penfold, Christopher N
Publicado 2013

Diversity and distribution of nuclease bacteriocins in bacterial genomes revealed using Hidden Markov Models

por Sharp, Connor, Bray, James, Housden, Nicholas G., Maiden, Martin C. J., Kleanthous, Colin
Publicado 2017

Targeted Killing of Pseudomonas aeruginosa by Pyocin G Occurs via the Hemin Transporter Hur

por Atanaskovic, Iva, Mosbahi, Khedidja, Sharp, Connor, Housden, Nicholas G., Kaminska, Renata, Walker, Daniel, Kleanthous, Colin
Publicado 2020

O-Antigen-Dependent Colicin Insensitivity of Uropathogenic Escherichia coli

por Sharp, Connor, Boinett, Christine, Cain, Amy, Housden, Nicholas G., Kumar, Sandip, Turner, Keith, Parkhill, Julian, Kleanthous, Colin
Publicado 2019

Transmembrane Epitope Delivery by Passive Protein Threading through the Pores of the OmpF Porin Trimer

por Lee, Sejeong, Housden, Nicholas G., Ionescu, Sandra A., Zimmer, Matthew H., Kaminska, Renata, Kleanthous, Colin, Bayley, Hagan
Publicado 2020

Porin threading drives receptor disengagement and establishes active colicin transport through Escherichia coli OmpF

por Francis, Marie‐Louise R, Webby, Melissa N, Housden, Nicholas G, Kaminska, Renata, Elliston, Emma, Chinthammit, Boonyaporn, Lukoyanova, Natalya, Kleanthous, Colin
Publicado 2021

A Force-Activated Trip Switch Triggers Rapid Dissociation of a Colicin from Its Immunity Protein

por Farrance, Oliver E., Hann, Eleanore, Kaminska, Renata, Housden, Nicholas G., Derrington, Sasha R., Kleanthous, Colin, Radford, Sheena E., Brockwell, David J.
Publicado 2013

Toxin import through the antibiotic efflux channel TolC

por Housden, Nicholas G., Webby, Melissa N., Lowe, Edward D., El-Baba, Tarick J., Kaminska, Renata, Redfield, Christina, Robinson, Carol V., Kleanthous, Colin
Publicado 2021

Native Desorption Electrospray Ionization Liberates Soluble and Membrane Protein Complexes from Surfaces

por Ambrose, Stephen, Housden, Nicholas G., Gupta, Kallol, Fan, Jieyuan, White, Paul, Yen, Hsin‐Yung, Marcoux, Julien, Kleanthous, Colin, Hopper, Jonathan T. S., Robinson, Carol V.
Publicado 2017

Structural and biophysical analysis of nuclease protein antibiotics

por Klein, Alexander, Wojdyla, Justyna Aleksandra, Joshi, Amar, Josts, Inokentijs, McCaughey, Laura C., Housden, Nicholas G., Kaminska, Renata, Byron, Olwyn, Walker, Daniel, Kleanthous, Colin
Publicado 2016

Directional Porin Binding of Intrinsically Disordered Protein Sequences Promotes Colicin Epitope Display in the Bacterial Periplasm

por Housden, Nicholas G., Rassam, Patrice, Lee, Sejeong, Samsudin, Firdaus, Kaminska, Renata, Sharp, Connor, Goult, Jonathan D., Francis, Marie-Louise, Khalid, Syma, Bayley, Hagan, Kleanthous, Colin
Publicado 2018

Correction to “Directional Porin Binding of Intrinsically Disordered Protein Sequences Promotes Colicin Epitope Display in the Bacterial Periplasm”

por Housden, Nicholas G., Rassam, Patrice, Lee, Sejeong, Samsudin, Firdaus, Kaminska, Renata, Sharp, Connor, Goult, Jonathan D., Francis, Marie-Louise, Khalid, Syma, Bayley, Hagan, Kleanthous, Colin
Publicado 2018

Peptidoglycan maturation controls outer membrane protein assembly

por Mamou, Gideon, Corona, Federico, Cohen-Khait, Ruth, Housden, Nicholas G., Yeung, Vivian, Sun, Dawei, Sridhar, Pooja, Pazos, Manuel, Knowles, Timothy J., Kleanthous, Colin, Vollmer, Waldemar
Publicado 2022

Exploitation of an iron transporter for bacterial protein antibiotic import

por White, Paul, Joshi, Amar, Rassam, Patrice, Housden, Nicholas G., Kaminska, Renata, Goult, Jonathan D., Redfield, Christina, McCaughey, Laura C., Walker, Daniel, Mohammed, Shabaz, Kleanthous, Colin
Publicado 2017

Colicin-Mediated Transport of DNA through the Iron Transporter FepA

por Cohen-Khait, Ruth, Harmalkar, Ameya, Pham, Phuong, Webby, Melissa N., Housden, Nicholas G., Elliston, Emma, Hopper, Jonathan T. S., Mohammed, Shabaz, Robinson, Carol V., Gray, Jeffrey J., Kleanthous, Colin
Publicado 2021

Targeted Delivery of Narrow-Spectrum Protein Antibiotics to the Lower Gastrointestinal Tract in a Murine Model of Escherichia coli Colonization

por Carpena, Nuria, Richards, Kerry, Bello Gonzalez, Teresita D. J., Bravo-Blas, Alberto, Housden, Nicholas G., Gerasimidis, Konstantinos, Milling, Simon W. F., Douce, Gillian, Malik, Danish J., Walker, Daniel
Publicado 2021

Pyocin S5 Import into Pseudomonas aeruginosa Reveals a Generic Mode of Bacteriocin Transport

por Behrens, Hannah M., Lowe, Edward D., Gault, Joseph, Housden, Nicholas G., Kaminska, Renata, Weber, T. Moritz, Thompson, Catriona M. A., Mislin, Gaëtan L. A., Schalk, Isabelle J., Walker, Daniel, Robinson, Carol V., Kleanthous, Colin
Publicado 2020

Lipids mediate supramolecular outer membrane protein assembly in bacteria

por Webby, Melissa N., Oluwole, Abraham O., Pedebos, Conrado, Inns, Patrick G., Olerinyova, Anna, Prakaash, Dheeraj, Housden, Nicholas G., Benn, Georgina, Sun, Dawei, Hoogenboom, Bart W., Kukura, Philipp, Mohammed, Shabaz, Robinson, Carol V., Khalid, Syma, Kleanthous, Colin
Publicado 2022

High-resolution mass spectrometry of small molecules bound to membrane proteins

por Gault, Joseph, Donlan, Joseph A. C., Liko, Idlir, Hopper, Jonathan T.S., Gupta, Kallol, Housden, Nicholas G., Struwe, Weston B., Marty, Michael T., Mize, Todd, Bechara, Cherine, Zhu, Ya, Wu, Beili, Kleanthous, Colin, Belov, Mikhail, Damoc, Eugen, Makarov, Alexander, Robinson, Carol V.
Publicado 2016

Supramolecular assemblies underpin turnover of outer membrane proteins in bacteria

por Rassam, Patrice, Copeland, Nikki A., Birkholz, Oliver, Tóth, Csaba, Chavent, Matthieu, Duncan, Anna L., Cross, Stephen J., Housden, Nicholas G., Kaminska, Renata, Seger, Urban, Quinn, Diana M., Garrod, Tamsin J., Sansom, Mark S.P., Piehler, Jacob, Baumann, Christoph G., Kleanthous, Colin
Publicado 2015