A preclinical orthotopic model for glioblastoma recapitulates key features of human tumors and demonstrates sensitivity to a combination of MEK and PI3K pathway inhibitors

por El Meskini, Rajaa, Iacovelli, Anthony J., Kulaga, Alan, Gumprecht, Michelle, Martin, Philip L., Baran, Maureen, Householder, Deborah B., Van Dyke, Terry, Weaver Ohler, Zoë
Publicado 2015

Loss of Brca1 and Trp53 in adult mouse mammary ductal epithelium results in development of hormone receptor-positive or hormone receptor-negative tumors, depending on inactivation...

por Szabova, Ludmila, Gordon, Melanie B., Lu, Lucy, Pate, Nathan, Bassel, Laura, Iacovelli, Anthony J., Karim, Baktiar, Homan, Philip J., Householder, Deborah B., Guerin, Theresa M., Burkett, Sandra, Day, Amanda M., Custer, Wendi, Weaver Ohler, Zoe
Publicado 2022

Pathway-Specific Engineered Mouse Allograft Models Functionally Recapitulate Human Serous Epithelial Ovarian Cancer

por Szabova, Ludmila, Bupp, Sujata, Kamal, Muhaymin, Householder, Deborah B., Hernandez, Lidia, Schlomer, Jerome J., Baran, Maureen L., Yi, Ming, Stephens, Robert M., Annunziata, Christina M., Martin, Philip L., Van Dyke, Terry A., Ohler, Zoe Weaver, Difilippantonio, Simone
Publicado 2014