Saccharopine, a lysine degradation intermediate, is a mitochondrial toxin

por Leandro, João, Houten, Sander M.
Publicado 2019

Acylcarnitines: Reflecting or Inflicting Insulin Resistance?

por Schooneman, Marieke G., Vaz, Frédéric M., Houten, Sander M., Soeters, Maarten R.
Publicado 2013

Toward an Understanding of the Structural and Mechanistic Aspects of Protein-Protein Interactions in 2-Oxoacid Dehydrogenase Complexes

por Nemeria, Natalia S., Zhang, Xu, Leandro, Joao, Zhou, Jieyu, Yang, Luying, Houten, Sander M., Jordan, Frank
Publicado 2021

The enzymology of mitochondrial fatty acid beta-oxidation and its application to follow-up analysis of positive neonatal screening results

por Wanders, Ronald J. A., Ruiter, Jos P. N., IJlst, Lodewijk, Waterham, Hans R., Houten, Sander M.
Publicado 2010

Critical assessment of human metabolic pathway databases: a stepping stone for future integration

por Stobbe, Miranda D, Houten, Sander M, Jansen, Gerbert A, van Kampen, Antoine HC, Moerland, Perry D
Publicado 2011

Inter-tissue coexpression network analysis reveals DPP4 as an important gene in heart to blood communication

por Long, Quan, Argmann, Carmen, Houten, Sander M., Huang, Tao, Peng, Siwu, Zhao, Yong, Tu, Zhidong, Zhu, Jun
Publicado 2016

Functional Versatility of the Human 2-Oxoadipate Dehydrogenase in the L-Lysine Degradation Pathway toward Its Non-Cognate Substrate 2-Oxopimelic Acid

por Nemeria, Natalia S., Nagy, Balint, Sanchez, Roberto, Zhang, Xu, Leandro, João, Ambrus, Attila, Houten, Sander M., Jordan, Frank
Publicado 2022

Changes in the Metabolome in Response to Low-Dose Exposure to Environmental Chemicals Used in Personal Care Products during Different Windows of Susceptibility

por Houten, Sander M., Chen, Jia, Belpoggi, Fiorella, Manservisi, Fabiana, Sánchez-Guijo, Alberto, Wudy, Stefan A., Teitelbaum, Susan L.
Publicado 2016

Venous Thoracic Outlet Syndrome Caused by Double Compression of the Axillosubclavian Vein: A Case Report

por Pesser, Niels, van den Houten, Marijn M.L., van Sambeek, Marc R.H.M., Teijink, Joep A.W.
Publicado 2020

Enhanced top‐down control of herbivore population growth on plants with impaired defences

por Legarrea, Saioa, Janssen, Arne, Dong, Lin, Glas, Joris J., van Houten, Yvonne M., Scala, Alessandra, Kant, Merijn R.
Publicado 2022

A case of hyperlysinemia identified by urine newborn screening

por Yeganeh, Mehdi, Auray‐Blais, Christiane, Maranda, Bruno, Sabovic, Amanda, DeVita, Robert J., Lazarus, Michael B., Houten, Sander M.
Publicado 2023

The metabolic footprint of aging in mice

por Houtkooper, Riekelt H., Argmann, Carmen, Houten, Sander M., Cantó, Carles, Jeninga, Ellen H., Andreux, Pénélope A., Thomas, Charles, Doenlen, Raphaël, Schoonjans, Kristina, Auwerx, Johan
Publicado 2011

Empagliflozin Decreases Lactate Generation in an NHE-1 Dependent Fashion and Increases α-Ketoglutarate Synthesis From Palmitate in Type II Diabetic Mouse Hearts

por Zhang, Hong, Uthman, Laween, Bakker, Diane, Sari, Sahinda, Chen, Sha, Hollmann, Markus W., Coronel, Ruben, Weber, Nina C., Houten, Sander M., van Weeghel, Michel, Zuurbier, Coert J.
Publicado 2020

Characterization and structure of the human lysine-2-oxoglutarate reductase domain, a novel therapeutic target for treatment of glutaric aciduria type 1

por Leandro, João, Khamrui, Susmita, Suebsuwong, Chalada, Chen, Peng-Jen, Secor, Cody, Dodatko, Tetyana, Yu, Chunli, Sanchez, Roberto, DeVita, Robert J., Houten, Sander M., Lazarus, Michael B.
Publicado 2022

Herbivory-associated degradation of tomato trichomes and its impact on biological control of Aculops lycopersici

por van Houten, Y. M., Glas, J. J., Hoogerbrugge, H., Rothe, J., Bolckmans, K. J. F., Simoni, S., van Arkel, J., Alba, J. M., Kant, M. R., Sabelis, M. W.
Publicado 2012

Changes in the status of p53 affect drug sensitivity to thymidylate synthase (TS) inhibitors by altering TS levels

por Giovannetti, E, Backus, H H J, Wouters, D, Ferreira, C G, van Houten, V M M, Brakenhoff, R H, Poupon, M-F, Azzarello, A, Pinedo, H M, Peters, G J
Publicado 2007

Bile Acid Binding Resin Improves Metabolic Control through the Induction of Energy Expenditure

por Watanabe, Mitsuhiro, Morimoto, Kohkichi, Houten, Sander M., Kaneko-Iwasaki, Nao, Sugizaki, Taichi, Horai, Yasushi, Mataki, Chikage, Sato, Hiroyuki, Murahashi, Karin, Arita, Eri, Schoonjans, Kristina, Suzuki, Tatsuya, Itoh, Hiroshi, Auwerx, Johan
Publicado 2012

Dietary restriction in the long-chain acyl-CoA dehydrogenase knockout mouse

por Diekman, Eugène F., van Weeghel, Michel, Suárez-Fariñas, Mayte, Argmann, Carmen, Ranea-Robles, Pablo, Wanders, Ronald J.A., Visser, Gepke, van der Made, Ingeborg, Creemers, Esther E., Houten, Sander M.
Publicado 2021

Muscle or liver-specific Sirt3 deficiency induces hyperacetylation of mitochondrial proteins without affecting global metabolic homeostasis

por Fernandez-Marcos, Pablo J., Jeninga, Ellen H., Canto, Carles, Harach, Taoufiq, de Boer, Vincent C. J., Andreux, Penelope, Moullan, Norman, Pirinen, Eija, Yamamoto, Hiroyasu, Houten, Sander M., Schoonjans, Kristina, Auwerx, Johan
Publicado 2012

Bezafibrate lowers very long-chain fatty acids in X-linked adrenoleukodystrophy fibroblasts by inhibiting fatty acid elongation

por Engelen, Marc, Schackmann, Martin J. A., Ofman, Rob, Sanders, Robert-Jan, Dijkstra, Inge M. E., Houten, Sander M., Fourcade, Stéphane, Pujol, Aurora, Poll-The, Bwee Tien, Wanders, Ronald J. A., Kemp, Stephan
Publicado 2012