Increased sarcolemmal Na(+)/H(+) exchange activity in hypertrophied myocytes from dogs with chronic atrioventricular block

por van Borren, Marcel M. G. J., Vos, Marc A., Houtman, Marien J. C., Antoons, Gudrun, Ravesloot, Jan H.
Publicado 2013

Identification of a PEST Sequence in Vertebrate K(IR)2.1 That Modifies Rectification

por Qile, Muge, Ji, Yuan, Houtman, Marien J. C., Veldhuis, Marlieke, Romunde, Fee, Kok, Bart, van der Heyden, Marcel A. G.
Publicado 2019

Short-term Variability of Repolarization Is Superior to Other Repolarization Parameters in the Evaluation of Diverse Antiarrhythmic Interventions in the Chronic Atrioventricular Bl...

por Bossu, Alexandre, Varkevisser, Rosanne, Beekman, Henriette D. M., Houtman, Marien J. C., van der Heyden, Marcel A. G., Vos, Marc A.
Publicado 2017

Development of I(KATP) Ion Channel Blockers Targeting Sulfonylurea Resistant Mutant K(IR)6.2 Based Channels for Treating DEND Syndrome

por Houtman, Marien J. C., Friesacher, Theres, Chen, Xingyu, Zangerl-Plessl, Eva-Maria, van der Heyden, Marcel A. G., Stary-Weinzinger, Anna
Publicado 2022

Glibenclamide and HMR1098 normalize Cantú syndrome‐associated gain‐of‐function currents

por Houtman, Marien J. C., Chen, Xingyu, Qile, Muge, Duran, Karen, van Haaften, Gijs, Stary‐Weinzinger, Anna, van der Heyden, Marcel A. G.
Publicado 2019

Computational Identification of Novel Kir6 Channel Inhibitors

por Chen, Xingyu, Garon, Arthur, Wieder, Marcus, Houtman, Marien J. C., Zangerl-Plessl, Eva-Maria, Langer, Thierry, van der Heyden, Marcel A. G., Stary-Weinzinger, Anna
Publicado 2019

Experimental Mapping of the Canine KCNJ2 and KCNJ12 Gene Structures and Functional Analysis of the Canine K(IR)2.2 ion Channel

por Houtman, Marien J. C., Takanari, Hiroki, Kok, Bart G. J. M., van Eck, Margot, Montagne, Denise R., Vos, Marc A., de Boer, Teun P., van der Heyden, Marcel A. G.
Publicado 2012

Class III antiarrhythmic drugs amiodarone and dronedarone impair K(IR)2.1 backward trafficking

por Ji, Yuan, Takanari, Hiroki, Qile, Muge, Nalos, Lukas, Houtman, Marien J.C., Romunde, Fee L., Heukers, Raimond, van Bergen en Henegouwen, Paul M.P., Vos, Marc A., van der Heyden, Marcel A.G.
Publicado 2017

PA-6 inhibits inward rectifier currents carried by V93I and D172N gain-of-function K(IR)2.1 channels, but increases channel protein expression

por Ji, Yuan, Veldhuis, Marlieke G., Zandvoort, Jantien, Romunde, Fee L., Houtman, Marien J. C., Duran, Karen, van Haaften, Gijs, Zangerl-Plessl, Eva-Maria, Takanari, Hiroki, Stary-Weinzinger, Anna, van der Heyden, Marcel A. G.
Publicado 2017

Selective late sodium current inhibitor GS‐458967 suppresses Torsades de Pointes by mostly affecting perpetuation but not initiation of the arrhythmia

por Bossu, Alexandre, Houtman, Marien J C, Meijborg, Veronique M F, Varkevisser, Rosanne, Beekman, Henriette D M, Dunnink, Albert, de Bakker, Jacques M T, Mollova, Nevena, Rajamani, Sridharan, Belardinelli, Luiz, van der Heyden, Marcel A G, Vos, Marc A
Publicado 2018

LUF7244, an allosteric modulator/activator of K(v)11.1 channels, counteracts dofetilide‐induced torsades de pointes arrhythmia in the chronic atrioventricular block dog model

por Qile, Muge, Beekman, Henriette D.M., Sprenkeler, David J., Houtman, Marien J.C., van Ham, Willem B., Stary‐Weinzinger, Anna, Beyl, Stanislav, Hering, Steffen, van den Berg, Dirk‐Jan, de Lange, Elizabeth C.M., Heitman, Laura H., IJzerman, Ad P., Vos, Marc A., van der Heyden, Marcel A.G.
Publicado 2019