IL-13 improves beta-cell survival and protects against IL-1beta-induced beta-cell death

por Rütti, Sabine, Howald, Cédric, Arous, Caroline, Dermitzakis, Emmanouil, Halban, Philippe A., Bouzakri, Karim
Publicado 2015

High-fat diet impacts more changes in beta-cell compared to alpha-cell transcriptome

por Dusaulcy, Rodolphe, Handgraaf, Sandra, Visentin, Florian, Howald, Cedric, Dermitzakis, Emmanouil T., Philippe, Jacques, Gosmain, Yvan
Publicado 2019

Angiogenin and Osteoprotegerin are type II muscle specific myokines protecting pancreatic beta-cells against proinflammatory cytokines

por Rutti, Sabine, Dusaulcy, Rodolphe, Hansen, Jakob S., Howald, Cédric, Dermitzakis, Emmanouil T., Pedersen, Bente K., Pinget, Michel, Plomgaard, Peter, Bouzakri, Karim
Publicado 2018

The Origins, Evolution, and Functional Potential of Alternative Splicing in Vertebrates

por Mudge, Jonathan M., Frankish, Adam, Fernandez-Banet, Julio, Alioto, Tyler, Derrien, Thomas, Howald, Cédric, Reymond, Alexandre, Guigó, Roderic, Hubbard, Tim, Harrow, Jennifer
Publicado 2011

The GENCODE pseudogene resource

por Pei, Baikang, Sisu, Cristina, Frankish, Adam, Howald, Cédric, Habegger, Lukas, Mu, Xinmeng Jasmine, Harte, Rachel, Balasubramanian, Suganthi, Tanzer, Andrea, Diekhans, Mark, Reymond, Alexandre, Hubbard, Tim J, Harrow, Jennifer, Gerstein, Mark B
Publicado 2012

The genomic landscape of human cellular circadian variation points to a novel role for the signalosome

por Gaspar, Ludmila, Howald, Cedric, Popadin, Konstantin, Maier, Bert, Mauvoisin, Daniel, Moriggi, Ermanno, Gutierrez-Arcelus, Maria, Falconnet, Emilie, Borel, Christelle, Kunz, Dieter, Kramer, Achim, Gachon, Frederic, Dermitzakis, Emmanouil T, Antonarakis, Stylianos E, Brown, Steven A
Publicado 2017

Combined genetic and transcriptome analysis of patients with SLE: distinct, targetable signatures for susceptibility and severity

por Panousis, Nikolaos I, Bertsias, George K, Ongen, Halit, Gergianaki, Irini, Tektonidou, Maria G, Trachana, Maria, Romano-Palumbo, Luciana, Bielser, Deborah, Howald, Cedric, Pamfil, Cristina, Fanouriakis, Antonis, Kosmara, Despoina, Repa, Argyro, Sidiropoulos, Prodromos, Dermitzakis, Emmanouil T, Boumpas, Dimitrios T
Publicado 2019

Combining RT-PCR-seq and RNA-seq to catalog all genic elements encoded in the human genome

por Howald, Cédric, Tanzer, Andrea, Chrast, Jacqueline, Kokocinski, Felix, Derrien, Thomas, Walters, Nathalie, Gonzalez, Jose M., Frankish, Adam, Aken, Bronwen L., Hourlier, Thibaut, Vogel, Jan-Hinnerk, White, Simon, Searle, Stephen, Harrow, Jennifer, Hubbard, Tim J., Guigó, Roderic, Reymond, Alexandre
Publicado 2012

Extension of human lncRNA transcripts by RACE coupled with long-read high-throughput sequencing (RACE-Seq)

por Lagarde, Julien, Uszczynska-Ratajczak, Barbara, Santoyo-Lopez, Javier, Gonzalez, Jose Manuel, Tapanari, Electra, Mudge, Jonathan M., Steward, Charles A., Wilming, Laurens, Tanzer, Andrea, Howald, Cédric, Chrast, Jacqueline, Vela-Boza, Alicia, Rueda, Antonio, Lopez-Domingo, Francisco J., Dopazo, Joaquin, Reymond, Alexandre, Guigó, Roderic, Harrow, Jennifer
Publicado 2016

Transcriptomic analyses reveal rhythmic and CLOCK-driven pathways in human skeletal muscle

por Perrin, Laurent, Loizides-Mangold, Ursula, Chanon, Stéphanie, Gobet, Cédric, Hulo, Nicolas, Isenegger, Laura, Weger, Benjamin D, Migliavacca, Eugenia, Charpagne, Aline, Betts, James A, Walhin, Jean-Philippe, Templeman, Iain, Stokes, Keith, Thompson, Dylan, Tsintzas, Kostas, Robert, Maud, Howald, Cedric, Riezman, Howard, Feige, Jerome N, Karagounis, Leonidas G, Johnston, Jonathan D, Dermitzakis, Emmanouil T, Gachon, Frédéric, Lefai, Etienne, Dibner, Charna
Publicado 2018

Genome-wide Association Study Identifies Shared Risk Loci Common to Two Malignancies in Golden Retrievers

por Tonomura, Noriko, Elvers, Ingegerd, Thomas, Rachael, Megquier, Kate, Turner-Maier, Jason, Howald, Cedric, Sarver, Aaron L., Swofford, Ross, Frantz, Aric M., Ito, Daisuke, Mauceli, Evan, Arendt, Maja, Noh, Hyun Ji, Koltookian, Michele, Biagi, Tara, Fryc, Sarah, Williams, Christina, Avery, Anne C., Kim, Jong-Hyuk, Barber, Lisa, Burgess, Kristine, Lander, Eric S., Karlsson, Elinor K., Azuma, Chieko, Modiano, Jaime F., Breen, Matthew, Lindblad-Toh, Kerstin
Publicado 2015

Integrated multi-omics reveals anaplerotic rewiring in methylmalonyl-CoA mutase deficiency

por Forny, Patrick, Bonilla, Ximena, Lamparter, David, Shao, Wenguang, Plessl, Tanja, Frei, Caroline, Bingisser, Anna, Goetze, Sandra, van Drogen, Audrey, Harshman, Keith, Pedrioli, Patrick G. A., Howald, Cedric, Poms, Martin, Traversi, Florian, Bürer, Céline, Cherkaoui, Sarah, Morscher, Raphael J., Simmons, Luke, Forny, Merima, Xenarios, Ioannis, Aebersold, Ruedi, Zamboni, Nicola, Rätsch, Gunnar, Dermitzakis, Emmanouil T., Wollscheid, Bernd, Baumgartner, Matthias R., Froese, D. Sean
Publicado 2023

Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B

por Karlsson, Elinor K, Sigurdsson, Snaevar, Ivansson, Emma, Thomas, Rachael, Elvers, Ingegerd, Wright, Jason, Howald, Cedric, Tonomura, Noriko, Perloski, Michele, Swofford, Ross, Biagi, Tara, Fryc, Sarah, Anderson, Nathan, Courtay-Cahen, Celine, Youell, Lisa, Ricketts, Sally L, Mandlebaum, Sarah, Rivera, Patricio, von Euler, Henrik, Kisseberth, William C, London, Cheryl A, Lander, Eric S, Couto, Guillermo, Comstock, Kenine, Starkey, Mike P, Modiano, Jaime F, Breen, Matthew, Lindblad-Toh, Kerstin
Publicado 2013

Evidence for Transcript Networks Composed of Chimeric RNAs in Human Cells

por Djebali, Sarah, Lagarde, Julien, Kapranov, Philipp, Lacroix, Vincent, Borel, Christelle, Mudge, Jonathan M., Howald, Cédric, Foissac, Sylvain, Ucla, Catherine, Chrast, Jacqueline, Ribeca, Paolo, Martin, David, Murray, Ryan R., Yang, Xinping, Ghamsari, Lila, Lin, Chenwei, Bell, Ian, Dumais, Erica, Drenkow, Jorg, Tress, Michael L., Gelpí, Josep Lluís, Orozco, Modesto, Valencia, Alfonso, van Berkum, Nynke L., Lajoie, Bryan R., Vidal, Marc, Stamatoyannopoulos, John, Batut, Philippe, Dobin, Alex, Harrow, Jennifer, Hubbard, Tim, Dekker, Job, Frankish, Adam, Salehi-Ashtiani, Kourosh, Reymond, Alexandre, Antonarakis, Stylianos E., Guigó, Roderic, Gingeras, Thomas R.
Publicado 2012

GENCODE: The reference human genome annotation for The ENCODE Project

por Harrow, Jennifer, Frankish, Adam, Gonzalez, Jose M., Tapanari, Electra, Diekhans, Mark, Kokocinski, Felix, Aken, Bronwen L., Barrell, Daniel, Zadissa, Amonida, Searle, Stephen, Barnes, If, Bignell, Alexandra, Boychenko, Veronika, Hunt, Toby, Kay, Mike, Mukherjee, Gaurab, Rajan, Jeena, Despacio-Reyes, Gloria, Saunders, Gary, Steward, Charles, Harte, Rachel, Lin, Michael, Howald, Cédric, Tanzer, Andrea, Derrien, Thomas, Chrast, Jacqueline, Walters, Nathalie, Balasubramanian, Suganthi, Pei, Baikang, Tress, Michael, Rodriguez, Jose Manuel, Ezkurdia, Iakes, van Baren, Jeltje, Brent, Michael, Haussler, David, Kellis, Manolis, Valencia, Alfonso, Reymond, Alexandre, Gerstein, Mark, Guigó, Roderic, Hubbard, Tim J.
Publicado 2012

Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D

por Viñuela, Ana, Varshney, Arushi, van de Bunt, Martijn, Prasad, Rashmi B., Asplund, Olof, Bennett, Amanda, Boehnke, Michael, Brown, Andrew A., Erdos, Michael R., Fadista, João, Hansson, Ola, Hatem, Gad, Howald, Cédric, Iyengar, Apoorva K., Johnson, Paul, Krus, Ulrika, MacDonald, Patrick E., Mahajan, Anubha, Manning Fox, Jocelyn E., Narisu, Narisu, Nylander, Vibe, Orchard, Peter, Oskolkov, Nikolay, Panousis, Nikolaos I., Payne, Anthony, Stitzel, Michael L., Vadlamudi, Swarooparani, Welch, Ryan, Collins, Francis S., Mohlke, Karen L., Gloyn, Anna L., Scott, Laura J., Dermitzakis, Emmanouil T., Groop, Leif, Parker, Stephen C. J., McCarthy, Mark I.
Publicado 2020

Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits

por Brown, Andrew A., Fernandez-Tajes, Juan J., Hong, Mun-gwan, Brorsson, Caroline A., Koivula, Robert W., Davtian, David, Dupuis, Théo, Sartori, Ambra, Michalettou, Theodora-Dafni, Forgie, Ian M., Adam, Jonathan, Allin, Kristine H., Caiazzo, Robert, Cederberg, Henna, De Masi, Federico, Elders, Petra J. M., Giordano, Giuseppe N., Haid, Mark, Hansen, Torben, Hansen, Tue H., Hattersley, Andrew T., Heggie, Alison J., Howald, Cédric, Jones, Angus G., Kokkola, Tarja, Laakso, Markku, Mahajan, Anubha, Mari, Andrea, McDonald, Timothy J., McEvoy, Donna, Mourby, Miranda, Musholt, Petra B., Nilsson, Birgitte, Pattou, Francois, Penet, Deborah, Raverdy, Violeta, Ridderstråle, Martin, Romano, Luciana, Rutters, Femke, Sharma, Sapna, Teare, Harriet, ‘t Hart, Leen, Tsirigos, Konstantinos D., Vangipurapu, Jagadish, Vestergaard, Henrik, Brunak, Søren, Franks, Paul W., Frost, Gary, Grallert, Harald, Jablonka, Bernd, McCarthy, Mark I., Pavo, Imre, Pedersen, Oluf, Ruetten, Hartmut, Walker, Mark, Adamski, Jerzy, Schwenk, Jochen M., Pearson, Ewan R., Dermitzakis, Emmanouil T., Viñuela, Ana
Publicado 2023

Landscape of transcription in human cells

por Djebali, Sarah, Davis, Carrie A., Merkel, Angelika, Dobin, Alex, Lassmann, Timo, Mortazavi, Ali M., Tanzer, Andrea, Lagarde, Julien, Lin, Wei, Schlesinger, Felix, Xue, Chenghai, Marinov, Georgi K., Khatun, Jainab, Williams, Brian A., Zaleski, Chris, Rozowsky, Joel, Röder, Maik, Kokocinski, Felix, Abdelhamid, Rehab F., Alioto, Tyler, Antoshechkin, Igor, Baer, Michael T., Bar, Nadav S., Batut, Philippe, Bell, Kimberly, Bell, Ian, Chakrabortty, Sudipto, Chen, Xian, Chrast, Jacqueline, Curado, Joao, Derrien, Thomas, Drenkow, Jorg, Dumais, Erica, Dumais, Jacqueline, Duttagupta, Radha, Falconnet, Emilie, Fastuca, Meagan, Fejes-Toth, Kata, Ferreira, Pedro, Foissac, Sylvain, Fullwood, Melissa J., Gao, Hui, Gonzalez, David, Gordon, Assaf, Gunawardena, Harsha, Howald, Cedric, Jha, Sonali, Johnson, Rory, Kapranov, Philipp, King, Brandon, Kingswood, Colin, Luo, Oscar J., Park, Eddie, Persaud, Kimberly, Preall, Jonathan B., Ribeca, Paolo, Risk, Brian, Robyr, Daniel, Sammeth, Michael, Schaffer, Lorian, See, Lei-Hoon, Shahab, Atif, Skancke, Jorgen, Suzuki, Ana Maria, Takahashi, Hazuki, Tilgner, Hagen, Trout, Diane, Walters, Nathalie, Wang, Huaien, Wrobel, John, Yu, Yanbao, Ruan, Xiaoan, Hayashizaki, Yoshihide, Harrow, Jennifer, Gerstein, Mark, Hubbard, Tim, Reymond, Alexandre, Antonarakis, Stylianos E., Hannon, Gregory, Giddings, Morgan C., Ruan, Yijun, Wold, Barbara, Carninci, Piero, Guigó, Roderic, Gingeras, Thomas R.
Publicado 2012

Comparative Analysis of the Transcriptome across Distant Species

por Gerstein, Mark B., Rozowsky, Joel, Yan, Koon-Kiu, Wang, Daifeng, Cheng, Chao, Brown, James B., Davis, Carrie A, Hillier, LaDeana, Sisu, Cristina, Li, Jingyi Jessica, Pei, Baikang, Harmanci, Arif O., Duff, Michael O., Djebali, Sarah, Alexander, Roger P., Alver, Burak H., Auerbach, Raymond, Bell, Kimberly, Bickel, Peter J., Boeck, Max E., Boley, Nathan P., Booth, Benjamin W., Cherbas, Lucy, Cherbas, Peter, Di, Chao, Dobin, Alex, Drenkow, Jorg, Ewing, Brent, Fang, Gang, Fastuca, Megan, Feingold, Elise A., Frankish, Adam, Gao, Guanjun, Good, Peter J., Guigó, Roderic, Hammonds, Ann, Harrow, Jen, Hoskins, Roger A., Howald, Cédric, Hu, Long, Huang, Haiyan, Hubbard, Tim J. P., Huynh, Chau, Jha, Sonali, Kasper, Dionna, Kato, Masaomi, Kaufman, Thomas C., Kitchen, Robert R., Ladewig, Erik, Lagarde, Julien, Lai, Eric, Leng, Jing, Lu, Zhi, MacCoss, Michael, May, Gemma, McWhirter, Rebecca, Merrihew, Gennifer, Miller, David M., Mortazavi, Ali, Murad, Rabi, Oliver, Brian, Olson, Sara, Park, Peter J., Pazin, Michael J., Perrimon, Norbert, Pervouchine, Dmitri, Reinke, Valerie, Reymond, Alexandre, Robinson, Garrett, Samsonova, Anastasia, Saunders, Gary I., Schlesinger, Felix, Sethi, Anurag, Slack, Frank J., Spencer, William C., Stoiber, Marcus H., Strasbourger, Pnina, Tanzer, Andrea, Thompson, Owen A., Wan, Kenneth H., Wang, Guilin, Wang, Huaien, Watkins, Kathie L., Wen, Jiayu, Wen, Kejia, Xue, Chenghai, Yang, Li, Yip, Kevin, Zaleski, Chris, Zhang, Yan, Zheng, Henry, Brenner, Steven E., Graveley, Brenton R., Celniker, Susan E., Gingeras, Thomas R, Waterston, Robert
Publicado 2014