Oligonucleotide Delivery to the Lung: Waiting to Inhale

por Kjems, Jørgen, Howard, Kenneth A
Publicado 2012

Nanomedicine

por Howard, Kenneth A, Vorup-Jensen, Thomas, Peer, Dan
Publicado 2016

Extended blood circulation and joint accumulation of a p(HPMA-co-AzMA)-based nanoconjugate in a murine model of rheumatoid arthritis

por Ebbesen, Morten F, Bienk, Konrad, Deleuran, Bent W, Howard, Kenneth A
Publicado 2014

Albumin-based drug delivery: harnessing nature to cure disease

por Larsen, Maja Thim, Kuhlmann, Matthias, Hvam, Michael Lykke, Howard, Kenneth A.
Publicado 2016

Mucosal Delivery of RNAi Therapeutics

por González, Borja Ballarín, Nielsen, Ebbe Bech, Thomsen, Troels Bo, Howard, Kenneth A.
Publicado 2012

Protection and Systemic Translocation of siRNA Following Oral Administration of Chitosan/siRNA Nanoparticles

por Ballarín-González, Borja, Dagnaes-Hansen, Frederik, Fenton, Robert A, Gao, Shan, Hein, San, Dong, Mingdong, Kjems, Jørgen, Howard, Kenneth A
Publicado 2013

Identification of a high-risk immunogenic prostate cancer patient subset as candidates for T-cell engager immunotherapy and the introduction of a novel albumin-fused anti-CD3 × ant...

por Glud, Eske N., Rasmussen, Martin, Zhang, Yonghui, Mandrup, Ole A., Salachan, Paul Vinu, Borre, Michael, Sørensen, Karina Dalsgaard, Howard, Kenneth A.
Publicado 2022

Pellet-free isolation of human and bovine milk extracellular vesicles by size-exclusion chromatography

por Blans, Kristine, Hansen, Maria S., Sørensen, Laila V., Hvam, Michael L., Howard, Kenneth A., Möller, Arne, Wiking, Lars, Larsen, Lotte B., Rasmussen, Jan T.
Publicado 2017

An albumin-angiotensin converting enzyme 2-based SARS-CoV-2 decoy with FcRn-driven half-life extension

por Fuchs, Elisabeth, Rudnik-Jansen, Imke, Dinesen, Anders, Selnihhin, Denis, Mandrup, Ole Aalund, Thiam, Kader, Kjems, Jørgen, Pedersen, Finn Skou, Howard, Kenneth A.
Publicado 2022

Comparative analysis of discrete exosome fractions obtained by differential centrifugation

por Jeppesen, Dennis K., Hvam, Michael L., Primdahl-Bengtson, Bjarke, Boysen, Anders T., Whitehead, Bradley, Dyrskjøt, Lars, Ørntoft, Torben F., Howard, Kenneth A., Ostenfeld, Marie S.
Publicado 2014

Programmable half-life and anti-tumour effects of bispecific T-cell engager-albumin fusions with tuned FcRn affinity

por Mandrup, Ole A., Ong, Sui Ching, Lykkemark, Simon, Dinesen, Anders, Rudnik-Jansen, Imke, Dagnæs-Hansen, Niels Frederik, Andersen, Jan Terje, Alvarez-Vallina, Luis, Howard, Kenneth A.
Publicado 2021

Regulation of Gdf5 expression in joint remodelling, repair and osteoarthritis

por Kania, Karolina, Colella, Fabio, Riemen, Anna H. K., Wang, Hui, Howard, Kenneth A., Aigner, Thomas, Dell’Accio, Francesco, Capellini, Terence D., Roelofs, Anke J., De Bari, Cosimo
Publicado 2020

An Albumin-Oligonucleotide Assembly for Potential Combinatorial Drug Delivery and Half-Life Extension Applications

por Kuhlmann, Matthias, Hamming, Jonas B.R., Voldum, Anders, Tsakiridou, Georgia, Larsen, Maja T., Schmøkel, Julie S., Sohn, Emil, Bienk, Konrad, Schaffert, David, Sørensen, Esben S., Wengel, Jesper, Dupont, Daniel M., Howard, Kenneth A.
Publicado 2017

Functionalized Acyclic (l)‐Threoninol Nucleic Acid Four‐Way Junction with High Stability In Vitro and In Vivo

por Märcher, Anders, Kumar, Vipin, Andersen, Veronica L., El‐Chami, Kassem, Nguyen, Thuy J. D., Skaanning, Mads K., Rudnik‐Jansen, Imke, Nielsen, Jesper S., Howard, Kenneth A., Kjems, Jørgen, Gothelf, Kurt V.
Publicado 2022

Targeting the IL-6–Yap–Snail signalling axis in synovial fibroblasts ameliorates inflammatory arthritis

por Symons, Rebecca A, Colella, Fabio, Collins, Fraser L, Rafipay, Alexandra J, Kania, Karolina, McClure, Jessica J, White, Nathan, Cunningham, Iain, Ashraf, Sadaf, Hay, Elizabeth, Mackenzie, Kevin S, Howard, Kenneth A, Riemen, Anna H K, Manzo, Antonio, Clark, Susan M, Roelofs, Anke J, De Bari, Cosimo
Publicado 2022

Intracellular bacteria engage a STING-TBK1-MVB12b pathway to enable paracrine cGAS-STING signaling

por Nandakumar, Ramya, Tschismarov, Roland, Meissner, Felix, Prabakaran, Thaneas, Krissanaprasit, Abhichart, Farahani, Ensieh, Zhang, Bao-cun, Assil, Sonia, Martin, Amandine, Bertrams, Wilhelm, Holm, Christian K, Ablasser, Andrea, Klause, Tanja, Thomsen, Martin K, Schmeck, Bernd, Howard, Kenneth A, Henry, Thomas, Gothelf, Kurt V, Decker, Thomas, Paludan, Søren R
Publicado 2019

The Immunomodulatory Drug Glatiramer Acetate is Also an Effective Antimicrobial Agent that Kills Gram-negative Bacteria

por Christiansen, Stig Hill, Murphy, Ronan A., Juul-Madsen, Kristian, Fredborg, Marlene, Hvam, Michael Lykke, Axelgaard, Esben, Skovdal, Sandra M., Meyer, Rikke Louise, Sørensen, Uffe B. Skov, Möller, Arne, Nyengaard, Jens Randel, Nørskov-Lauritsen, Niels, Wang, Mikala, Gadjeva, Mihaela, Howard, Kenneth A., Davies, Jane C., Petersen, Eskild, Vorup-Jensen, Thomas
Publicado 2017

Tumor targeted 4-1BB agonist antibody-albumin fusions with high affinity to FcRn induce anti-tumor immunity without toxicity

por Hangiu, Oana, Compte, Marta, Dinesen, Anders, Navarro, Rocio, Tapia-Galisteo, Antonio, Mandrup, Ole A., Erce-Llamazares, Ainhoa, Lázaro-Gorines, Rodrigo, Nehme-Álvarez, Daniel, Domínguez-Alonso, Carmen, Harwood, Seandean L., Alfonso, Carlos, Blanco, Belen, Rubio-Pérez, Laura, Jiménez-Reinoso, Anaïs, Díez-Alonso, Laura, Blanco, Francisco J., Sanz, Laura, Howard, Kenneth A., Álvarez-Vallina, Luis
Publicado 2022