An Evaluation of the Potential of NMR Spectroscopy and Computational Modelling Methods to Inform Biopharmaceutical Formulations

por Pandya, Akash, Howard, Mark J., Zloh, Mire, Dalby, Paul A.
Publicado 2018

Structural Definition Is Important for the Propagation of the Yeast [PSI(+)] Prion

por Marchante, Ricardo, Rowe, Michelle, Zenthon, Jo, Howard, Mark J., Tuite, Mick F.
Publicado 2013

Conserved differences in protein sequence determine the human pathogenicity of Ebolaviruses

por Pappalardo, Morena, Juliá, Miguel, Howard, Mark J., Rossman, Jeremy S., Michaelis, Martin, Wass, Mark N.
Publicado 2016

Membrane remodeling by the M2 amphipathic helix drives influenza virus membrane scission

por Martyna, Agnieszka, Bahsoun, Basma, Badham, Matthew D., Srinivasan, Saipraveen, Howard, Mark J., Rossman, Jeremy S.
Publicado 2017

(1)H NMR Spectroscopy Profiling of Metabolic Reprogramming of Chinese Hamster Ovary Cells upon a Temperature Shift during Culture

por Wagstaff, Jane L., Masterton, Rosalyn J., Povey, Jane F., Smales, C. Mark, Howard, Mark J.
Publicado 2013

Q2DSTD NMR deciphers epitope-mapping variability for peptide recognition of integrin αvβ6

por Sorge, Jessica L., Wagstaff, Jane L., Rowe, Michelle L., Williamson, Richard A., Howard, Mark J.
Publicado 2015

Combined ligand-observe (19)F and protein-observe (15)N,(1)H-HSQC NMR suggests phenylalanine as the key Δ-somatostatin residue recognized by human protein disulfide isomerase

por Richards, Kirsty L., Rowe, Michelle L., Hudson, Paul B., Williamson, Richard A., Howard, Mark J.
Publicado 2016

(19)F NMR spectroscopy monitors ligand binding to recombinantly fluorine-labelled b′x from human protein disulphide isomerase (hPDI)

por Curtis-Marof, Rose, Doko, Denisa, Rowe, Michelle L., Richards, Kirsty L., Williamson, Richard A., Howard, Mark J.
Publicado 2014

New insights into stop codon recognition by eRF1

por Blanchet, Sandra, Rowe, Michelle, Von der Haar, Tobias, Fabret, Céline, Demais, Stéphane, Howard, Mark J., Namy, Olivier
Publicado 2015

Inappropriate expression of the translation elongation factor 1A disrupts genome stability and metabolism

por Tarrant, Daniel J., Stirpe, Mariarita, Rowe, Michelle, Howard, Mark J., von der Haar, Tobias, Gourlay, Campbell W.
Publicado 2016

NMR metabolomics reveals effects of Cryptosporidium infections on host cell metabolome

por Miller, Christopher N., Panagos, Charalampos G., Mosedale, William R. T., Kváč, Martin, Howard, Mark J., Tsaousis, Anastasios D.
Publicado 2019

High-resolution NMR studies of structure and dynamics of human ERp27 indicate extensive interdomain flexibility

por Amin, Nader T., Wallis, A. Katrine, Wells, Stephen A., Rowe, Michelle L., Williamson, Richard A., Howard, Mark J., Freedman, Robert B.
Publicado 2013

Measuring protein reduction potentials using (15)N HSQC NMR spectroscopy()

por Taylor, Samantha L., Crawley-Snowdon, Harriet, Wagstaff, Jane L., Rowe, Michelle L., Shepherd, Mark, Williamson, Richard A., Howard, Mark J.
Publicado 2013

CydDC-mediated reductant export in Escherichia coli controls the transcriptional wiring of energy metabolism and combats nitrosative stress

por Holyoake, Louise V., Hunt, Stuart, Sanguinetti, Guido, Cook, Gregory M., Howard, Mark J., Rowe, Michelle L., Poole, Robert K., Shepherd, Mark
Publicado 2016

The Fanconi Anemia DNA Repair Pathway Is Regulated by an Interaction between Ubiquitin and the E2-like Fold Domain of FANCL

por Miles, Jennifer A., Frost, Mark G., Carroll, Eilis, Rowe, Michelle L., Howard, Mark J., Sidhu, Ateesh, Chaugule, Viduth K., Alpi, Arno F., Walden, Helen
Publicado 2015

Supramolecular Self‐Sorting Networks using Hydrogen‐Bonding Motifs

por Coubrough, Heather M., van der Lubbe, Stephanie C. C., Hetherington, Kristina, Minard, Aisling, Pask, Christopher, Howard, Mark J., Fonseca Guerra, Célia, Wilson, Andrew J.
Publicado 2018

Structural Guided Scaffold Phage Display Libraries as a Source of Bio-Therapeutics

por Man, Y. K. Stella, DiCara, Danielle, Chan, Nicole, Vessillier, Sandrine, Mather, Stephen J., Rowe, Michelle L., Howard, Mark J., Marshall, John F., Nissim, Ahuva
Publicado 2013

A family of small, cyclic peptides buried in preproalbumin since the Eocene epoch

por Fisher, Mark F., Zhang, Jingjing, Taylor, Nicolas L., Howard, Mark J., Berkowitz, Oliver, Debowski, Aleksandra W., Behsaz, Bahar, Whelan, James, Pevzner, Pavel A., Mylne, Joshua S.
Publicado 2018

Protein Disulfide-Isomerase Interacts with a Substrate Protein at All Stages along Its Folding Pathway

por Irvine, Alistair G., Wallis, A. Katrine, Sanghera, Narinder, Rowe, Michelle L., Ruddock, Lloyd W., Howard, Mark J., Williamson, Richard A., Blindauer, Claudia A., Freedman, Robert B.
Publicado 2014

Amylin and beta amyloid proteins interact to form amorphous heterocomplexes with enhanced toxicity in neuronal cells

por Bharadwaj, Prashant, Solomon, Tanya, Sahoo, Bikash R., Ignasiak, Katarzyna, Gaskin, Scott, Rowles, Joanne, Verdile, Giuseppe, Howard, Mark J., Bond, Charles S., Ramamoorthy, Ayyalusamy, Martins, Ralph N., Newsholme, Philip
Publicado 2020