Tissue fixation and the effect of molecular fixatives on downstream staining procedures

por Howat, William J., Wilson, Beverley A.
Publicado 2014

Elevated Levels of G-Quadruplex Formation in Human Stomach and Liver Cancer Tissues

por Biffi, Giulia, Tannahill, David, Miller, Jodi, Howat, William J., Balasubramanian, Shankar
Publicado 2014

A metadata-aware application for remote scoring and exchange of tissue microarray images

por Morris, Lorna, Tsui, Andrew, Crichton, Charles, Harris, Steve, Maccallum, Peter H, Howat, William J, Davies, Jim, Brenton, James D, Caldas, Carlos
Publicado 2013

Antibody validation of immunohistochemistry for biomarker discovery: Recommendations of a consortium of academic and pharmaceutical based histopathology researchers

por Howat, William J., Lewis, Arthur, Jones, Phillipa, Kampf, Caroline, Pontén, Fredrik, van der Loos, Chris M., Gray, Neil, Womack, Chris, Warford, Anthony
Publicado 2014

SPARC independent drug delivery and antitumour effects of nab-paclitaxel in genetically engineered mice

por Neesse, Albrecht, Frese, Kristopher K, Chan, Derek S, Bapiro, Tashinga E, Howat, William J, Richards, Frances M, Ellenrieder, Volker, Jodrell, Duncan I, Tuveson, David A
Publicado 2014

Hypoxia-induced nitric oxide production and tumour perfusion is inhibited by pegylated arginine deiminase (ADI-PEG20)

por Burrows, Natalie, Cane, Gaelle, Robson, Mathew, Gaude, Edoardo, J. Howat, William, Szlosarek, Peter W., Pedley, R. Barbara, Frezza, Christian, Ashcroft, Margaret, Maxwell, Patrick H.
Publicado 2016

Proliferation Tumour Marker Network (PTM-NET) for the identification of tumour region in Ki67 stained breast cancer whole slide images

por Joseph, Jesuchristopher, Roudier, Martine P., Narayanan, Priya Lakshmi, Augulis, Renaldas, Ros, Vidalba Rocher, Pritchard, Alison, Gerrard, Joe, Laurinavicius, Arvydas, Harrington, Elizabeth A., Barrett, J. Carl, Howat, William J.
Publicado 2019

Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma

por Cook, Natalie, Frese, Kristopher K., Bapiro, Tashinga E., Jacobetz, Michael A., Gopinathan, Aarthi, Miller, Jodi L., Rao, Sudhir S., Demuth, Tim, Howat, William J., Jodrell, Duncan I., Tuveson, David A.
Publicado 2012

Detection of colorectal dysplasia using fluorescently labelled lectins

por Kuo, Joe Chin-Hun, Ibrahim, Ashraf E. K., Dawson, Sarah, Parashar, Deepak, Howat, William J., Guttula, Kiran, Miller, Richard, Fearnhead, Nicola S., Winton, Douglas J., Neves, André A., Brindle, Kevin M.
Publicado 2016

MRI with hyperpolarised [1-(13)C]pyruvate detects advanced pancreatic preneoplasia prior to invasive disease in a mouse model

por Serrao, Eva M, Kettunen, Mikko I, Rodrigues, Tiago B, Dzien, Piotr, Wright, Alan J, Gopinathan, Aarthi, Gallagher, Ferdia A, Lewis, David Y, Frese, Kristopher K, Almeida, Jaime, Howat, William J, Tuveson, David A, Brindle, Kevin M
Publicado 2016

NOTCH1 mediates a switch between two distinct secretomes during senescence

por Hoare, Matthew, Ito, Yoko, Kang, Tae-Won, Weekes, Michael P., Matheson, Nicholas J., Patten, Daniel A., Shetty, Shishir, Parry, Aled J., Menon, Suraj, Salama, Rafik, Antrobus, Robin, Tomimatsu, Kosuke, Howat, William, Lehner, Paul J., Zender, Lars, Narita, Masashi
Publicado 2016

Crowdsourcing for translational research: analysis of biomarker expression using cancer microarrays

por Lawson, Jonathan, Robinson-Vyas, Rupesh J, McQuillan, Janette P, Paterson, Andy, Christie, Sarah, Kidza-Griffiths, Matthew, McDuffus, Leigh-Anne, Moutasim, Karwan A, Shaw, Emily C, Kiltie, Anne E, Howat, William J, Hanby, Andrew M, Thomas, Gareth J, Smittenaar, Peter
Publicado 2017

An Examination of the Association between FOXA1 Staining Level and Biochemical Recurrence following Salvage Radiation Therapy for Recurrent Prostate Cancer

por Heckman, Michael G., Robinson, Jessica L., Tzou, Katherine S., Parker, Alexander S., Wu, Kevin J., Hilton, Tracy W., Howat, William J., Miller, Jodi L., Kreinest, Pamela A., Pisansky, Thomas M., Schild, Steven E., Peterson, Jennifer L., Vallow, Laura A., Carroll, Jason S., Buskirk, Steven J.
Publicado 2016

pRAD50: a novel and clinically applicable pharmacodynamic biomarker of both ATM and ATR inhibition identified using mass spectrometry and immunohistochemistry

por Jones, Gemma N., Rooney, Claire, Griffin, Nicola, Roudier, Martine, Young, Lucy A., Garcia-Trinidad, Antonio, Hughes, Gareth D., Whiteaker, Jeffrey R., Wilson, Zena, Odedra, Rajesh, Zhao, Lei, Ivey, Richard G., Howat, William J., Harrington, Elizabeth A., Barrett, J. Carl, Ramos-Montoya, Antonio, Lau, Alan, Paulovich, Amanda G., Cadogan, Elaine B., Pierce, Andrew J.
Publicado 2018

Tumor genomic, transcriptomic, and immune profiling characterizes differential response to first‐line platinum chemotherapy in high grade serous ovarian cancer

por Weberpals, Johanne I., Pugh, Trevor J., Marco‐Casanova, Paola, Goss, Glenwood D., Andrews Wright, Natalie, Rath, Prisni, Torchia, Jonathon, Fortuna, Alexander, Jones, Gemma N., Roudier, Martine P., Bernard, Laurence, Lo, Bryan, Torti, Dax, Leon, Alberto, Marsh, Kayla, Hodgson, Darren, Duciaume, Marc, Howat, William J., Lukashchuk, Natalia, Lazic, Stanley E., Whelan, Doreen, Sekhon, Harmanjatinder S.
Publicado 2021

HES6 drives a critical AR transcriptional programme to induce castration-resistant prostate cancer through activation of an E2F1-mediated cell cycle network

por Ramos-Montoya, Antonio, Lamb, Alastair D, Russell, Roslin, Carroll, Thomas, Jurmeister, Sarah, Galeano-Dalmau, Nuria, Massie, Charlie E, Boren, Joan, Bon, Helene, Theodorou, Vasiliki, Vias, Maria, Shaw, Greg L, Sharma, Naomi L, Ross-Adams, Helen, Scott, Helen E, Vowler, Sarah L, Howat, William J, Warren, Anne Y, Wooster, Richard F, Mills, Ian G, Neal, David E
Publicado 2014

Application of phage display to high throughput antibody generation and characterization

por Schofield, Darren J, Pope, Anthony R, Clementel, Veronica, Buckell, Jenny, Chapple, Susan DJ, Clarke, Kay F, Conquer, Jennie S, Crofts, Anna M, Crowther, Sandra RE, Dyson, Michael R, Flack, Gillian, Griffin, Gareth J, Hooks, Yvette, Howat, William J, Kolb-Kokocinski, Anja, Kunze, Susan, Martin, Cecile D, Maslen, Gareth L, Mitchell, Joanne N, O'Sullivan, Maureen, Perera, Rajika L, Roake, Wendy, Shadbolt, S Paul, Vincent, Karen J, Warford, Anthony, Wilson, Wendy E, Xie, Jane, Young, Joyce L, McCafferty, John
Publicado 2007

Heterogeneity of luminal breast cancer characterised by immunohistochemical expression of basal markers

por Sung, Hyuna, Garcia-Closas, Montserrat, Chang-Claude, Jenny, Blows, Fiona M, Ali, H Raza, Figueroa, Jonine, Nevanlinna, Heli, Fagerholm, Rainer, Heikkilä, Päivi, Blomqvist, Carl, Giles, Graham G, Milne, Roger L, Southey, Melissa C, McLean, Catriona, Mannermaa, Arto, Kosma, Veli-Matti, Kataja, Vesa, Sironen, Reijo, Couch, Fergus J, Olson, Janet E, Hallberg, Emily, Olswold, Curtis, Cox, Angela, Cross, Simon S, Kraft, Peter, Tamimi, Rulla M, Eliassen, A Heather, Schmidt, Marjanka K, Bolla, Manjeet K, Wang, Qin, Easton, Douglas, Howat, William J, Coulson, Penny, Pharoah, Paul DP, Sherman, Mark E, Yang, Xiaohong R
Publicado 2016

High‐throughput automated scoring of Ki67 in breast cancer tissue microarrays from the Breast Cancer Association Consortium

por Abubakar, Mustapha, Howat, William J, Daley, Frances, Zabaglo, Lila, McDuffus, Leigh‐Anne, Blows, Fiona, Coulson, Penny, Raza Ali, H, Benitez, Javier, Milne, Roger, Brenner, Herman, Stegmaier, Christa, Mannermaa, Arto, Chang‐Claude, Jenny, Rudolph, Anja, Sinn, Peter, Couch, Fergus J, Tollenaar, Rob A.E.M., Devilee, Peter, Figueroa, Jonine, Sherman, Mark E, Lissowska, Jolanta, Hewitt, Stephen, Eccles, Diana, Hooning, Maartje J, Hollestelle, Antoinette, WM Martens, John, HM van Deurzen, Carolien, Investigators, kConFab, Bolla, Manjeet K, Wang, Qin, Jones, Michael, Schoemaker, Minouk, Broeks, Annegien, van Leeuwen, Flora E, Van't Veer, Laura, Swerdlow, Anthony J, Orr, Nick, Dowsett, Mitch, Easton, Douglas, Schmidt, Marjanka K, Pharoah, Paul D, Garcia‐Closas, Montserrat
Publicado 2016

Crowdsourcing the General Public for Large Scale Molecular Pathology Studies in Cancer

por Candido dos Reis, Francisco J., Lynn, Stuart, Ali, H. Raza, Eccles, Diana, Hanby, Andrew, Provenzano, Elena, Caldas, Carlos, Howat, William J., McDuffus, Leigh-Anne, Liu, Bin, Daley, Frances, Coulson, Penny, Vyas, Rupesh J., Harris, Leslie M., Owens, Joanna M., Carton, Amy F.M., McQuillan, Janette P., Paterson, Andy M., Hirji, Zohra, Christie, Sarah K., Holmes, Amber R., Schmidt, Marjanka K., Garcia-Closas, Montserrat, Easton, Douglas F., Bolla, Manjeet K., Wang, Qin, Benitez, Javier, Milne, Roger L., Mannermaa, Arto, Couch, Fergus, Devilee, Peter, Tollenaar, Robert A.E.M., Seynaeve, Caroline, Cox, Angela, Cross, Simon S., Blows, Fiona M., Sanders, Joyce, de Groot, Renate, Figueroa, Jonine, Sherman, Mark, Hooning, Maartje, Brenner, Hermann, Holleczek, Bernd, Stegmaier, Christa, Lintott, Chris, Pharoah, Paul D.P.
Publicado 2015