Targeted genome editing restores T cell differentiation in a humanized X-SCID pluripotent stem cell disease model

por Alzubi, Jamal, Pallant, Celeste, Mussolino, Claudio, Howe, Steven J., Thrasher, Adrian J., Cathomen, Toni
Publicado 2017

Inhibition of Mitochondrial Complex I Impairs Release of α-Galactosidase by Jurkat Cells

por Lambert, Jonathan R. A., Howe, Steven J., Rahim, Ahad A., Burke, Derek G., Heales, Simon J. R.
Publicado 2019

Minicircle DNA Provides Enhanced and Prolonged Transgene Expression Following Airway Gene Transfer

por Munye, Mustafa M., Tagalakis, Aristides D., Barnes, Josephine L., Brown, Rachel E., McAnulty, Robin J., Howe, Steven J., Hart, Stephen L.
Publicado 2016

Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hematopoietic cel...

por Zhang, Fang, Thornhill, Susannah I., Howe, Steven J., Ulaganathan, Meera, Schambach, Axel, Sinclair, Joanna, Kinnon, Christine, Gaspar, H. Bobby, Antoniou, Michael, Thrasher, Adrian J.
Publicado 2007

Perinatal Gene Transfer to the Liver

por McKay, Tristan R, Rahim, Ahad A, Buckley, Suzanne M.K, Ward, Natalie J, Chan, Jerry K.Y, Howe, Steven J, Waddington, Simon N
Publicado 2011

Evidence for Contribution of CD4+CD25+ Regulatory T Cells in Maintaining Immune Tolerance to Human Factor IX following Perinatal Adenovirus Vector Delivery

por Nivsarkar, Megha S., Buckley, Suzanne M. K., Parker, Alan L., Perocheau, Dany, McKay, Tristan R., Rahim, Ahad A., Howe, Steven J., Waddington, Simon N.
Publicado 2015

Lentiviral vectors can be used for full-length dystrophin gene therapy

por Counsell, John R., Asgarian, Zeinab, Meng, Jinhong, Ferrer, Veronica, Vink, Conrad A., Howe, Steven J., Waddington, Simon N., Thrasher, Adrian J., Muntoni, Francesco, Morgan, Jennifer E., Danos, Olivier
Publicado 2017

Lentiviral vectors can be used for full-length dystrophin gene therapy

por Counsell, John R., Asgarian, Zeinab, Meng, Jinhong, Ferrer, Veronica, Vink, Conrad A., Howe, Steven J., Waddington, Simon N., Thrasher, Adrian J., Muntoni, Francesco, Morgan, Jennifer E., Danos, Olivier
Publicado 2017

Erratum: Lentiviral vectors can be used for full-length dystrophin gene therapy

por Counsell, John R., Asgarian, Zeinab, Meng, Jinhong, Ferrer, Veronica, Vink, Conrad A., Howe, Steven J., Waddington, Simon N., Thrasher, Adrian J., Muntoni, Francesco, Morgan, Jennifer E., Danos, Olivier
Publicado 2017

Enhancement of mouse hematopoietic stem/progenitor cell function via transient gene delivery using integration-deficient lentiviral vectors

por Alonso-Ferrero, Maria E., van Til, Niek P., Bartolovic, Kerol, Mata, Márcia F., Wagemaker, Gerard, Moulding, Dale, Williams, David A., Kinnon, Christine, Waddington, Simon N., Milsom, Michael D., Howe, Steven J.
Publicado 2018

Real-Time Definition of Non-Randomness in the Distribution of Genomic Events

por Abel, Ulrich, Deichmann, Annette, Bartholomae, Cynthia, Schwarzwaelder, Kerstin, Glimm, Hanno, Howe, Steven, Thrasher, Adrian, Garrigue, Alexandrine, Hacein-Bey-Abina, Salima, Cavazzana-Calvo, Marina, Fischer, Alain, Jaeger, Dirk, von Kalle, Christof, Schmidt, Manfred
Publicado 2007

Systemic gene delivery following intravenous administration of AAV9 to fetal and neonatal mice and late-gestation nonhuman primates

por Mattar, Citra N., Wong, Andrew M. S., Hoefer, Klemens, Alonso-Ferrero, Maria E., Buckley, Suzanne M. K., Howe, Steven J., Cooper, Jonathan D., Waddington, Simon N., Chan, Jerry K. Y., Rahim, Ahad A.
Publicado 2015

Eliminating HIV-1 Packaging Sequences from Lentiviral Vector Proviruses Enhances Safety and Expedites Gene Transfer for Gene Therapy

por Vink, Conrad A., Counsell, John R., Perocheau, Dany P., Karda, Rajvinder, Buckley, Suzanne M.K., Brugman, Martijn H., Galla, Melanie, Schambach, Axel, McKay, Tristan R., Waddington, Simon N., Howe, Steven J.
Publicado 2017

In vivo bioimaging with tissue-specific transcription factor activated luciferase reporters

por Buckley, Suzanne M. K., Delhove, Juliette M. K. M., Perocheau, Dany P., Karda, Rajvinder, Rahim, Ahad A., Howe, Steven J., Ward, Natalie J., Birrell, Mark A., Belvisi, Maria G., Arbuthnot, Patrick, Johnson, Mark R., Waddington, Simon N., McKay, Tristan R.
Publicado 2015

Vps33b is crucial for structural and functional hepatocyte polarity

por Hanley, Joanna, Dhar, Dipok Kumar, Mazzacuva, Francesca, Fiadeiro, Rebeca, Burden, Jemima J., Lyne, Anne-Marie, Smith, Holly, Straatman-Iwanowska, Anna, Banushi, Blerida, Virasami, Alex, Mills, Kevin, Lemaigre, Frédéric P., Knisely, A.S., Howe, Steven, Sebire, Neil, Waddington, Simon N., Paulusma, Coen C., Clayton, Peter, Gissen, Paul
Publicado 2017

Foamy Virus Vectors Transduce Visceral Organs and Hippocampal Structures following In Vivo Delivery to Neonatal Mice

por Counsell, John R., Karda, Rajvinder, Diaz, Juan Antinao, Carey, Louise, Wiktorowicz, Tatiana, Buckley, Suzanne M.K., Ameri, Shima, Ng, Joanne, Baruteau, Julien, Almeida, Filipa, de Silva, Rohan, Simone, Roberto, Lugarà, Eleonora, Lignani, Gabriele, Lindemann, Dirk, Rethwilm, Axel, Rahim, Ahad A., Waddington, Simon N., Howe, Steven J.
Publicado 2018

Rapid Lentiviral Vector Producer Cell Line Generation Using a Single DNA Construct

por Chen, Yu Hua, Pallant, Celeste, Sampson, Christopher J., Boiti, Alessia, Johnson, Sabine, Brazauskas, Pijus, Hardwicke, Philip, Marongiu, Michela, Marinova, Vanesa M., Carmo, Marlene, Sweeney, Nathan P., Richard, Ashkenaz, Shillings, Anthony, Archibald, Peter, Puschmann, Eva, Mouzon, Bernadette, Grose, David, Mendez-Tavio, Miriam, Chen, Mao Xiang, Warr, Stephen R.C., Senussi, Tarik, Carter, Paul S., Baker, Sean, Jung, Cindy, Brugman, Martijn H., Howe, Steven J., Vink, Conrad A.
Publicado 2020

Site- and allele-specific polycomb dysregulation in T-cell leukaemia

por Navarro, Jean-Marc, Touzart, Aurore, Pradel, Lydie C., Loosveld, Marie, Koubi, Myriam, Fenouil, Romain, Le Noir, Sandrine, Maqbool, Muhammad Ahmad, Morgado, Ester, Gregoire, Claude, Jaeger, Sebastien, Mamessier, Emilie, Pignon, Charles, Hacein-Bey-Abina, Salima, Malissen, Bernard, Gut, Marta, Gut, Ivo G., Dombret, Hervé, Macintyre, Elizabeth A., Howe, Steven J., Gaspar, H. Bobby, Thrasher, Adrian J., Ifrah, Norbert, Payet-Bornet, Dominique, Duprez, Estelle, Andrau, Jean-Christophe, Asnafi, Vahid, Nadel, Bertrand
Publicado 2015