Linkage analysis of a derived glucose phenotype in the Genetic Analysis Workshop 13 simulated data using a variety of Haseman-Elston based regression methods

por Cordell, Heather J, Howson, Joanna MM, Clayton, David G
Publicado 2003

Genetic Analysis of Adult-Onset Autoimmune Diabetes

por Howson, Joanna M.M., Rosinger, Silke, Smyth, Deborah J., Boehm, Bernhard O., Todd, John A.
Publicado 2011

Evidence of association with type 1 diabetes in the SLC11A1 gene region

por Yang, Jennie HM, Downes, Kate, Howson, Joanna MM, Nutland, Sarah, Stevens, Helen E, Walker, Neil M, Todd, John A
Publicado 2011

Evidence That HLA Class I and II Associations With Type 1 Diabetes, Autoantibodies to GAD and Autoantibodies to IA-2, Are Distinct

por Howson, Joanna M.M., Stevens, Helen, Smyth, Deborah J., Walker, Neil M., Chandler, Kyla A., Bingley, Polly J., Todd, John A.
Publicado 2011

FUT2 Nonsecretor Status Links Type 1 Diabetes Susceptibility and Resistance to Infection

por Smyth, Deborah J., Cooper, Jason D., Howson, Joanna M.M., Clarke, Pamela, Downes, Kate, Mistry, Trupti, Stevens, Helen, Walker, Neil M., Todd, John A.
Publicado 2011

An Allele of IKZF1 (Ikaros) Conferring Susceptibility to Childhood Acute Lymphoblastic Leukemia Protects Against Type 1 Diabetes

por Swafford, Austin D.-E., Howson, Joanna M.M., Davison, Lucy J., Wallace, Chris, Smyth, Deborah J., Schuilenburg, Helen, Maisuria-Armer, Meeta, Mistry, Trupti, Lenardo, Michael J., Todd, John A.
Publicado 2011

Analysis of polymorphisms in 16 genes in type 1 diabetes that have been associated with other immune-mediated diseases

por Smyth, Deborah J, Howson, Joanna MM, Payne, Felicity, Maier, Lisa M, Bailey, Rebecca, Holland, Kieran, Lowe, Christopher E, Cooper, Jason D, Hulme, John S, Vella, Adrian, Dahlman, Ingrid, Lam, Alex C, Nutland, Sarah, Walker, Neil M, Twells, Rebecca CJ, Todd, John A
Publicado 2006

A hybrid qPCR/SNP array approach allows cost efficient assessment of KIR gene copy numbers in large samples

por Pontikos, Nikolas, Smyth, Deborah J, Schuilenburg, Helen, Howson, Joanna MM, Walker, Neil M, Burren, Oliver S, Guo, Hui, Onengut-Gumuscu, Suna, Chen, Wei-Min, Concannon, Patrick, Rich, Stephen S, Jayaraman, Jyothi, Jiang, Wei, Traherne, James A, Trowsdale, John, Todd, John A, Wallace, Chris
Publicado 2014

Detection and correction of artefacts in estimation of rare copy number variants and analysis of rare deletions in type 1 diabetes

por Cooper, Nicholas J., Shtir, Corina J., Smyth, Deborah J., Guo, Hui, Swafford, Austin D., Zanda, Manuela, Hurles, Matthew E., Walker, Neil M., Plagnol, Vincent, Cooper, Jason D., Howson, Joanna M.M., Burren, Oliver S., Onengut-Gumuscu, Suna, Rich, Stephen S., Todd, John A.
Publicado 2015

Evidence of Gene-Gene Interaction and Age-at-Diagnosis Effects in Type 1 Diabetes

por Howson, Joanna M.M., Cooper, Jason D., Smyth, Deborah J., Walker, Neil M., Stevens, Helen, She, Jin-Xiong, Eisenbarth, George S., Rewers, Marian, Todd, John A., Akolkar, Beena, Concannon, Patrick, Erlich, Henry A., Julier, Cécile, Morahan, Grant, Nerup, Jørn, Nierras, Concepcion, Pociot, Flemming, Rich, Stephen S.
Publicado 2012

Mendelian randomization for studying the effects of perturbing drug targets

por Gill, Dipender, Georgakis, Marios K., Walker, Venexia M., Schmidt, A. Floriaan, Gkatzionis, Apostolos, Freitag, Daniel F., Finan, Chris, Hingorani, Aroon D., Howson, Joanna M.M., Burgess, Stephen, Swerdlow, Daniel I., Davey Smith, George, Holmes, Michael V., Dichgans, Martin, Scott, Robert A, Zheng, Jie, Psaty, Bruce M., Davies, Neil M.
Publicado 2021

Plasma Proteomics to Identify Drug Targets for Ischemic Heart Disease

por Mazidi, Mohsen, Wright, Neil, Yao, Pang, Kartsonaki, Christiana, Millwood, Iona Y., Fry, Hannah, Said, Saredo, Pozarickij, Alfred, Pei, Pei, Chen, Yiping, Avery, Daniel, Du, Huaidong, Schmidt, Dan Valle, Yang, Ling, Lv, Jun, Yu, Canqing, Chen, Junshi, Hill, Michael, Holmes, Michael V., Howson, Joanna M.M., Peto, Richard, Collins, Rory, Bennett, Derrick A., Walters, Robin G., Li, Liming, Clarke, Robert, Chen, Zhengming
Publicado 2023

Long-range DNA looping and gene expression analyses identify DEXI as an autoimmune disease candidate gene

por Davison, Lucy J., Wallace, Chris, Cooper, Jason D., Cope, Nathan F., Wilson, Nicola K., Smyth, Deborah J., Howson, Joanna M.M., Saleh, Nada, Al-Jeffery, Abdullah, Angus, Karen L., Stevens, Helen E., Nutland, Sarah, Duley, Simon, Coulson, Richard M.R., Walker, Neil M., Burren, Oliver S., Rice, Catherine M., Cambien, Francois, Zeller, Tanja, Munzel, Thomas, Lackner, Karl, Blankenberg, Stefan, Fraser, Peter, Gottgens, Berthold, Todd, John A.
Publicado 2012

The Bangladesh Risk of Acute Vascular Events (BRAVE) Study: objectives and design

por Chowdhury, Rajiv, Alam, Dewan S., Fakir, Ismail Ibrahim, Adnan, Sheikh Daud, Naheed, Aliya, Tasmin, Ishrat, Monower, Md Mostafa, Hossain, Farzana, Hossain, Fatema Mahjabin, Rahman, Md Mostafizur, Afrin, Sadia, Roy, Anjan Kumar, Akter, Minara, Sume, Sima Akter, Biswas, Ajoy Kumer, Pennells, Lisa, Surendran, Praveen, Young, Robin D., Spackman, Sarah A., Hasan, Khaled, Harshfield, Eric, Sheikh, Nasir, Houghton, Richard, Saleheen, Danish, Howson, Joanna MM, Butterworth, Adam S., Raqib, Rubhana, Majumder, Abdulla Al Shafi, Danesh, John, Di Angelantonio, Emanuele
Publicado 2015

Hepatocyte mARC1 promotes fatty liver disease

por Lewis, Lara C., Chen, Lingyan, Hameed, L. Shahul, Kitchen, Robert R., Maroteau, Cyrielle, Nagarajan, Shilpa R., Norlin, Jenny, Daly, Charlotte E., Szczerbinska, Iwona, Hjuler, Sara Toftegaard, Patel, Rahul, Livingstone, Eilidh J., Durrant, Tom N., Wondimu, Elisabeth, BasuRay, Soumik, Chandran, Anandhakumar, Lee, Wan-Hung, Hu, Sile, Gilboa, Barak, Grandi, Megan E., Toledo, Enrique M., Erikat, Abdullah H.A., Hodson, Leanne, Haynes, William G., Pursell, Natalie W., Coppieters, Ken, Fleckner, Jan, Howson, Joanna M.M., Andersen, Birgitte, Ruby, Maxwell A.
Publicado 2023

Genetic invalidation of Lp-PLA(2) as a therapeutic target: Large-scale study of five functional Lp-PLA(2)-lowering alleles

por Gregson, John M, Freitag, Daniel F, Surendran, Praveen, Stitziel, Nathan O, Chowdhury, Rajiv, Burgess, Stephen, Kaptoge, Stephen, Gao, Pei, Staley, James R, Willeit, Peter, Nielsen, Sune F, Caslake, Muriel, Trompet, Stella, Polfus, Linda M, Kuulasmaa, Kari, Kontto, Jukka, Perola, Markus, Blankenberg, Stefan, Veronesi, Giovanni, Gianfagna, Francesco, Männistö, Satu, Kimura, Akinori, Lin, Honghuang, Reilly, Dermot F, Gorski, Mathias, Mijatovic, Vladan, Munroe, Patricia B, Ehret, Georg B, Thompson, Alex, Uria-Nickelsen, Maria, Malarstig, Anders, Dehghan, Abbas, Vogt, Thomas F, Sasaoka, Taishi, Takeuchi, Fumihiko, Kato, Norihiro, Yamada, Yoshiji, Kee, Frank, Müller-Nurasyid, Martina, Ferrières, Jean, Arveiler, Dominique, Amouyel, Philippe, Salomaa, Veikko, Boerwinkle, Eric, Thompson, Simon G, Ford, Ian, Wouter Jukema, J, Sattar, Naveed, Packard, Chris J, Shafi Majumder, Abdulla al, Alam, Dewan S, Deloukas, Panos, Schunkert, Heribert, Samani, Nilesh J, Kathiresan, Sekar, Nordestgaard, Børge G, Saleheen, Danish, Howson, Joanna MM, Di Angelantonio, Emanuele, Butterworth, Adam S, Danesh, John
Publicado 2016

Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease

por Zhao, Wei, Rasheed, Asif, Tikkanen, Emmi, Lee, Jung-Jin, Butterworth, Adam S, Howson, Joanna MM, Assimes, Themistocles L, Chowdhury, Rajiv, Orho-Melander, Marju, Damrauer, Scott, Small, Aeron, Asma, Senay, Imamura, Minako, Yamauch, Toshimasa, Chambers, John C, Chen, Peng, Sapkota, Bishwa R, Shah, Nabi, Jabeen, Sehrish, Surendran, Praveen, Lu, Yingchang, Zhang, Weihua, Imran, Atif, Abbas, Shahid, Majeed, Faisal, Trindade, Kevin, Qamar, Nadeem, Mallick, Nadeem Hayyat, Yaqoob, Zia, Saghir, Tahir, Rizvi, Syed Nadeem Hasan, Memon, Anis, Rasheed, Syed Zahed, Memon, Fazal-ur-Rehman, Mehmood, Khalid, Ahmed, Naveeduddin, Qureshi, Irshad Hussain, Tanveer-us-Salam, Iqbal, Wasim, Malik, Uzma, Mehra, Narinder, Kuo, Jane Z, Sheu, Wayne H-H, Guo, Xiuqing, Hsiung, Chao A, Juang, Jyh-Ming J, Taylor, Kent D, Hung, Yi-Jen, Lee, Wen-Jane, Quertermous, Thomas, Lee, I-Te, Hsu, Chih-Cheng, Bottinger, Erwin P., Ralhan, Sarju, Teo, Yik Ying, Wang, Tzung-Dau, Alam, Dewan S, Di Angelantonio, Emanuele, Epstein, Steve, Nielsen, Sune F, Nordestgaard, Børge G, Tybjaerg-Hansen, Anne, Young, Robin, Benn, Marianne, Frikke-Schmidt, Ruth, Kamstrup, Pia R, Biobank, Michigan, Jukema, J Wouter, Sattar, Naveed, Smit, Roelof, Chung, Ren-Hua, Liang, Kae-Woei, Anand, Sonia, Sanghera, Dharambir K, Ripatti, Samuli, Loos, Ruth J.F., Kooner, Jaspal S, Tai, E Shyong, Rotter, Jerome I, Chen, Yii-Der Ida, Frossard, Philippe, Maeda, Shiro, Kadowaki, Takashi, Reilly, Muredach, Pare, Guillaume, Melander, Olle, Salomaa, Veikko, Rader, Daniel J, Danesh, John, Voight, Benjamin F, Saleheen, Danish
Publicado 2017

The Polygenic and Monogenic Basis of Blood Traits and Diseases

por Vuckovic, Dragana, Bao, Erik L., Akbari, Parsa, Lareau, Caleb A., Mousas, Abdou, Jiang, Tao, Chen, Ming-Huei, Raffield, Laura M., Tardaguila, Manuel, Huffman, Jennifer E., Ritchie, Scott C., Megy, Karyn, Ponstingl, Hannes, Penkett, Christopher J., Albers, Patrick K., Wigdor, Emilie M., Sakaue, Saori, Moscati, Arden, Manansala, Regina, Lo, Ken Sin, Qian, Huijun, Akiyama, Masato, Bartz, Traci M., Ben-Shlomo, Yoav, Beswick, Andrew, Bork-Jensen, Jette, Bottinger, Erwin P., Brody, Jennifer A., van Rooij, Frank J.A., Chitrala, Kumaraswamy N., Wilson, Peter W.F., Choquet, Hélène, Danesh, John, Di Angelantonio, Emanuele, Dimou, Niki, Ding, Jingzhong, Elliott, Paul, Esko, Tõnu, Evans, Michele K., Felix, Stephan B., Floyd, James S., Broer, Linda, Grarup, Niels, Guo, Michael H., Guo, Qi, Greinacher, Andreas, Haessler, Jeff, Hansen, Torben, Howson, Joanna M.M., Huang, Wei, Jorgenson, Eric, Kacprowski, Tim, Kähönen, Mika, Kamatani, Yoichiro, Kanai, Masahiro, Karthikeyan, Savita, Koskeridis, Fotios, Lange, Leslie A., Lehtimäki, Terho, Linneberg, Allan, Liu, Yongmei, Lyytikäinen, Leo-Pekka, Manichaikul, Ani, Matsuda, Koichi, Mohlke, Karen L., Mononen, Nina, Murakami, Yoshinori, Nadkarni, Girish N., Nikus, Kjell, Pankratz, Nathan, Pedersen, Oluf, Preuss, Michael, Psaty, Bruce M., Raitakari, Olli T., Rich, Stephen S., Rodriguez, Benjamin A.T., Rosen, Jonathan D., Rotter, Jerome I., Schubert, Petra, Spracklen, Cassandra N., Surendran, Praveen, Tang, Hua, Tardif, Jean-Claude, Ghanbari, Mohsen, Völker, Uwe, Völzke, Henry, Watkins, Nicholas A., Weiss, Stefan, Cai, Na, Kundu, Kousik, Watt, Stephen B., Walter, Klaudia, Zonderman, Alan B., Cho, Kelly, Li, Yun, Loos, Ruth J.F., Knight, Julian C., Georges, Michel, Stegle, Oliver, Evangelou, Evangelos, Okada, Yukinori, Roberts, David J., Inouye, Michael, Johnson, Andrew D., Auer, Paul L., Astle, William J., Reiner, Alexander P., Butterworth, Adam S., Ouwehand, Willem H., Lettre, Guillaume, Sankaran, Vijay G., Soranzo, Nicole
Publicado 2020

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

por Webb, Thomas R., Erdmann, Jeanette, Stirrups, Kathleen E., Stitziel, Nathan O., Masca, Nicholas G.D., Jansen, Henning, Kanoni, Stavroula, Nelson, Christopher P., Ferrario, Paola G., König, Inke R., Eicher, John D., Johnson, Andrew D., Hamby, Stephen E., Betsholtz, Christer, Ruusalepp, Arno, Franzén, Oscar, Schadt, Eric E., Björkegren, Johan L.M., Weeke, Peter E., Auer, Paul L., Schick, Ursula M., Lu, Yingchang, Zhang, He, Dube, Marie-Pierre, Goel, Anuj, Farrall, Martin, Peloso, Gina M., Won, Hong-Hee, Do, Ron, van Iperen, Erik, Kruppa, Jochen, Mahajan, Anubha, Scott, Robert A., Willenborg, Christina, Braund, Peter S., van Capelleveen, Julian C., Doney, Alex S.F., Donnelly, Louise A., Asselta, Rosanna, Merlini, Pier A., Duga, Stefano, Marziliano, Nicola, Denny, Josh C., Shaffer, Christian, El-Mokhtari, Nour Eddine, Franke, Andre, Heilmann, Stefanie, Hengstenberg, Christian, Hoffmann, Per, Holmen, Oddgeir L., Hveem, Kristian, Jansson, Jan-Håkan, Jöckel, Karl-Heinz, Kessler, Thorsten, Kriebel, Jennifer, Laugwitz, Karl L., Marouli, Eirini, Martinelli, Nicola, McCarthy, Mark I., Van Zuydam, Natalie R., Meisinger, Christa, Esko, Tõnu, Mihailov, Evelin, Escher, Stefan A., Alver, Maris, Moebus, Susanne, Morris, Andrew D., Virtamo, Jarma, Nikpay, Majid, Olivieri, Oliviero, Provost, Sylvie, AlQarawi, Alaa, Robertson, Neil R., Akinsansya, Karen O., Reilly, Dermot F., Vogt, Thomas F., Yin, Wu, Asselbergs, Folkert W., Kooperberg, Charles, Jackson, Rebecca D., Stahl, Eli, Müller-Nurasyid, Martina, Strauch, Konstantin, Varga, Tibor V., Waldenberger, Melanie, Zeng, Lingyao, Chowdhury, Rajiv, Salomaa, Veikko, Ford, Ian, Jukema, J. Wouter, Amouyel, Philippe, Kontto, Jukka, Nordestgaard, Børge G., Ferrières, Jean, Saleheen, Danish, Sattar, Naveed, Surendran, Praveen, Wagner, Aline, Young, Robin, Howson, Joanna M.M., Butterworth, Adam S., Danesh, John, Ardissino, Diego, Bottinger, Erwin P., Erbel, Raimund, Franks, Paul W., Girelli, Domenico, Hall, Alistair S., Hovingh, G. Kees, Kastrati, Adnan, Lieb, Wolfgang, Meitinger, Thomas, Kraus, William E., Shah, Svati H., McPherson, Ruth, Orho-Melander, Marju, Melander, Olle, Metspalu, Andres, Palmer, Colin N.A., Peters, Annette, Rader, Daniel J., Reilly, Muredach P., Loos, Ruth J.F., Reiner, Alex P., Roden, Dan M., Tardif, Jean-Claude, Thompson, John R., Wareham, Nicholas J., Watkins, Hugh, Willer, Cristen J., Samani, Nilesh J., Schunkert, Heribert, Deloukas, Panos, Kathiresan, Sekar
Publicado 2017

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

por Surendran, Praveen, Drenos, Fotios, Young, Robin, Warren, Helen, Cook, James P, Manning, Alisa K, Grarup, Niels, Sim, Xueling, Barnes, Daniel R, Witkowska, Kate, Staley, James R, Tragante, Vinicius, Tukiainen, Taru, Yaghootkar, Hanieh, Masca, Nicholas, Freitag, Daniel F, Ferreira, Teresa, Giannakopoulou, Olga, Tinker, Andrew, Harakalova, Magdalena, Mihailov, Evelin, Liu, Chunyu, Kraja, Aldi T, Fallgaard Nielsen, Sune, Rasheed, Asif, Samuel, Maria, Zhao, Wei, Bonnycastle, Lori L, Jackson, Anne U, Narisu, Narisu, Swift, Amy J, Southam, Lorraine, Marten, Jonathan, Huyghe, Jeroen R, Stančáková, Alena, Fava, Cristiano, Ohlsson, Therese, Matchan, Angela, Stirrups, Kathleen E, Bork-Jensen, Jette, Gjesing, Anette P, Kontto, Jukka, Perola, Markus, Shaw-Hawkins, Susan, Havulinna, Aki S, Zhang, He, Donnelly, Louise A, Groves, Christopher J, Rayner, N William, Neville, Matt J, Robertson, Neil R, Yiorkas, Andrianos M, Herzig, Karl-Heinz, Kajantie, Eero, Zhang, Weihua, Willems, Sara M, Lannfelt, Lars, Malerba, Giovanni, Soranzo, Nicole, Trabetti, Elisabetta, Verweij, Niek, Evangelou, Evangelos, Moayyeri, Alireza, Vergnaud, Anne-Claire, Nelson, Christopher P, Poveda, Alaitz, Varga, Tibor V, Caslake, Muriel, de Craen, Anton JM, Trompet, Stella, Luan, Jian’an, Scott, Robert A, Harris, Sarah E, Liewald, David CM, Marioni, Riccardo, Menni, Cristina, Farmaki, Aliki-Eleni, Hallmans, Göran, Renström, Frida, Huffman, Jennifer E, Hassinen, Maija, Burgess, Stephen, Vasan, Ramachandran S, Felix, Janine F, Uria-Nickelsen, Maria, Malarstig, Anders, Reily, Dermot F, Hoek, Maarten, Vogt, Thomas, Lin, Honghuang, Lieb, Wolfgang, Traylor, Matthew, Markus, Hugh F, Highland, Heather M, Justice, Anne E, Marouli, Eirini, Lindström, Jaana, Uusitupa, Matti, Komulainen, Pirjo, Lakka, Timo A, Rauramaa, Rainer, Polasek, Ozren, Rudan, Igor, Rolandsson, Olov, Franks, Paul W, Dedoussis, George, Spector, Timothy D, Jousilahti, Pekka, Männistö, Satu, Deary, Ian J, Starr, John M, Langenberg, Claudia, Wareham, Nick J, Brown, Morris J, Dominiczak, Anna F, Connell, John M, Jukema, J Wouter, Sattar, Naveed, Ford, Ian, Packard, Chris J, Esko, Tõnu, Mägi, Reedik, Metspalu, Andres, de Boer, Rudolf A, van der Meer, Peter, van der Harst, Pim, Gambaro, Giovanni, Ingelsson, Erik, Lind, Lars, de Bakker, Paul IW, Numans, Mattijs E, Brandslund, Ivan, Christensen, Cramer, Petersen, Eva RB, Korpi-Hyövälti, Eeva, Oksa, Heikki, Chambers, John C, Kooner, Jaspal S, Blakemore, Alexandra IF, Franks, Steve, Jarvelin, Marjo-Riitta, Husemoen, Lise L, Linneberg, Allan, Skaaby, Tea, Thuesen, Betina, Karpe, Fredrik, Tuomilehto, Jaakko, Doney, Alex SF, Morris, Andrew D, Palmer, Colin NA, Holmen, Oddgeir Lingaas, Hveem, Kristian, Willer, Cristen J, Tuomi, Tiinamaija, Groop, Leif, Käräjämäki, AnneMari, Palotie, Aarno, Ripatti, Samuli, Salomaa, Veikko, Alam, Dewan S, Shafi Majumder, Abdulla al, Di Angelantonio, Emanuele, Chowdhury, Rajiv, McCarthy, Mark I, Poulter, Neil, Stanton, Alice V, Sever, Peter, Amouyel, Philippe, Arveiler, Dominique, Blankenberg, Stefan, Ferrières, Jean, Kee, Frank, Kuulasmaa, Kari, Müller-Nurasyid, Martina, Veronesi, Giovanni, Virtamo, Jarmo, Deloukas, Panos, Elliott, Paul, Zeggini, Eleftheria, Kathiresan, Sekar, Melander, Olle, Kuusisto, Johanna, Laakso, Markku, Padmanabhan, Sandosh, Porteous, David, Hayward, Caroline, Scotland, Generation, Collins, Francis S, Mohlke, Karen L, Hansen, Torben, Pedersen, Oluf, Boehnke, Michael, Stringham, Heather M, Frossard, Philippe, Newton-Cheh, Christopher, Tobin, Martin D, Nordestgaard, Børge Grønne, Caulfield, Mark J, Mahajan, Anubha, Morris, Andrew P, Tomaszewski, Maciej, Samani, Nilesh J, Saleheen, Danish, Asselbergs, Folkert W, Lindgren, Cecilia M, Danesh, John, Wain, Louise V, Butterworth, Adam S, Howson, Joanna MM, Munroe, Patricia B
Publicado 2016