Roles for endocytosis in lentiviral replication

por Marsh, Mark, Pelchen-Matthews, Annegret, Hoxie, James A.
Publicado 1997

Tetherin downmodulation by SIVmac Nef lost with the H196Q escape variant is restored by an upstream variant

por Schouest, Blake, Leslie, George J., Hoxie, James A., Maness, Nicholas J.
Publicado 2020

CCR5 interaction with HIV-1 Env contributes to Env-induced depletion of CD4 T cells in vitro and in vivo

por Tsao, Li-Chung, Guo, Haitao, Jeffrey, Jerry, Hoxie, James A., Su, Lishan
Publicado 2016

Molecular Architectures of Trimeric SIV and HIV-1 Envelope Glycoproteins on Intact Viruses: Strain-Dependent Variation in Quaternary Structure

por White, Tommi A., Bartesaghi, Alberto, Borgnia, Mario J., Meyerson, Joel R., de la Cruz, M. Jason V., Bess, Julian W., Nandwani, Rachna, Hoxie, James A., Lifson, Jeffrey D., Milne, Jacqueline L. S., Subramaniam, Sriram
Publicado 2010

Interactions of peptide triazole thiols with Env gp120 induce irreversible breakdown and inactivation of HIV-1 virions

por Bastian, Arangassery Rosemary, Contarino, Mark, Bailey, Lauren D, Aneja, Rachna, Moreira, Diogo Rodrigo Magalhaes, Freedman, Kevin, McFadden, Karyn, Duffy, Caitlin, Emileh, Ali, Leslie, George, Jacobson, Jeffrey M, Hoxie, James A, Chaiken, Irwin
Publicado 2013

V3 Loop Truncations in HIV-1 Envelope Impart Resistance to Coreceptor Inhibitors and Enhanced Sensitivity to Neutralizing Antibodies

por Laakso, Meg M, Lee, Fang-Hua, Haggarty, Beth, Agrawal, Caroline, Nolan, Katrina M, Biscone, Mark, Romano, Josephine, Jordan, Andrea P. O, Leslie, George J, Meissner, Eric G, Su, Lishan, Hoxie, James A, Doms, Robert W
Publicado 2007

Phorbol Esters and SDF-1 Induce Rapid Endocytosis and Down Modulation of the Chemokine Receptor CXCR4

por Signoret, Natalie, Oldridge, Joanne, Pelchen-Matthews, Annegret, Klasse, Per J., Tran, Thanh, Brass, Lawrence F., Rosenkilde, Mette M., Schwartz, Thue W., Holmes, William, Dallas, Walt, Luther, Michael A., Wells, Timothy N.C., Hoxie, James A., Marsh, Mark
Publicado 1997

Increased surface expression of HIV-1 envelope is associated with improved antibody response in vaccinia prime/protein boost immunization

por Hogan, Michael J., Conde-Motter, Angela, Jordan, Andrea P.O., Yang, Lifei, Cleveland, Brad, Guo, Wenjin, Romano, Josephine, Ni, Houping, Pardi, Norbert, LaBranche, Celia C., Montefiori, David C., Hu, Shiu-Lok, Hoxie, James A., Weissman, Drew
Publicado 2018

Antigenic conservation and immunogenicity of the HIV coreceptor binding site

por Decker, Julie M., Bibollet-Ruche, Frederic, Wei, Xiping, Wang, Shuyi, Levy, David N., Wang, Wenquan, Delaporte, Eric, Peeters, Martine, Derdeyn, Cynthia A., Allen, Susan, Hunter, Eric, Saag, Michael S., Hoxie, James A., Hahn, Beatrice H., Kwong, Peter D., Robinson, James E., Shaw, George M.
Publicado 2005

Potent and Broad Inhibition of HIV-1 by a Peptide from the gp41 Heptad Repeat-2 Domain Conjugated to the CXCR4 Amino Terminus

por Leslie, George J., Wang, Jianbin, Richardson, Max W., Haggarty, Beth S., Hua, Kevin L., Duong, Jennifer, Secreto, Anthony J., Jordon, Andrea P. O., Romano, Josephine, Kumar, Kritika E., DeClercq, Joshua J., Gregory, Philip D., June, Carl H., Root, Michael J., Riley, James L., Holmes, Michael C., Hoxie, James A.
Publicado 2016

The Impact of SIV-Induced Immunodeficiency on Clinical Manifestation, Immune Response, and Viral Dynamics in SARS-CoV-2 Coinfection

por Melton, Alexandra, Rowe, Lori A, Penney, Toni, Krzykwa, Clara, Goff, Kelly, Scheuermann, Sarah, Melton, Hunter J, Williams, Kelsey, Golden, Nadia, Green, Kristyn Moore, Smith, Brandon, Russell-Lodrigue, Kasi, Dufour, Jason P, Doyle-Meyers, Lara A, Schiro, Faith, Aye, Pyone P, Lifson, Jeffery D, Beddingfield, Brandon J, Blair, Robert V, Bohm, Rudolf P, Kolls, Jay K, Rappaport, Jay, Hoxie, James A, Maness, Nicholas J
Publicado 2023

Broad coverage of neutralization-resistant SIV strains by second-generation SIV-specific antibodies targeting the region involved in binding CD4

por Welles, Hugh C., King, Hannah A. D., Nettey, Leonard, Cavett, Nicole, Gorman, Jason, Zhou, Tongqing, Tsybovsky, Yaroslav, Du, Renguang, Song, Kaimei, Nguyen, Richard, Ambrozak, David, Ransier, Amy, Schramm, Chaim A., Doria-Rose, Nicole A., Swanstrom, Adrienne E., Hoxie, James A., LaBranche, Celia, Montefiori, David C., Douek, Daniel C., Kwong, Peter D., Mascola, John R., Roederer, Mario, Mason, Rosemarie D.
Publicado 2022

Engineering HIV-Resistant Human CD4+ T Cells with CXCR4-Specific Zinc-Finger Nucleases

por Wilen, Craig B., Wang, Jianbin, Tilton, John C., Miller, Jeffrey C., Kim, Kenneth A., Rebar, Edward J., Sherrill-Mix, Scott A., Patro, Sean C., Secreto, Anthony J., Jordan, Andrea P. O., Lee, Gary, Kahn, Joshua, Aye, Pyone P., Bunnell, Bruce A., Lackner, Andrew A., Hoxie, James A., Danet-Desnoyers, Gwenn A., Bushman, Frederic D., Riley, James L., Gregory, Philip D., June, Carl H., Holmes, Michael C., Doms, Robert W.
Publicado 2011

The pigtail macaque (Macaca nemestrina) model of COVID-19 reproduces diverse clinical outcomes and reveals new and complex signatures of disease

por Melton, Alexandra, Doyle-Meyers, Lara A., Blair, Robert V., Midkiff, Cecily, Melton, Hunter J., Russell-Lodrigue, Kasi, Aye, Pyone P., Schiro, Faith, Fahlberg, Marissa, Szeltner, Dawn, Spencer, Skye, Beddingfield, Brandon J., Goff, Kelly, Golden, Nadia, Penney, Toni, Picou, Breanna, Hensley, Krystle, Chandler, Kristin E., Plante, Jessica A., Plante, Kenneth S., Weaver, Scott C., Roy, Chad J., Hoxie, James A., Gao, Hongmei, Montefiori, David C., Mankowski, Joseph L., Bohm, Rudolf P., Rappaport, Jay, Maness, Nicholas J.
Publicado 2021

A cellular trafficking signal in the SIV envelope protein cytoplasmic domain is strongly selected for in pathogenic infection

por Lawrence, Scott P., Elser, Samra E., Torben, Workineh, Blair, Robert V., Pahar, Bapi, Aye, Pyone P., Schiro, Faith, Szeltner, Dawn, Doyle-Meyers, Lara A., Haggarty, Beth S., Jordan, Andrea P. O., Romano, Josephine, Leslie, George J., Alvarez, Xavier, O’Connor, David H., Wiseman, Roger W., Fennessey, Christine M., Li, Yuan, Piatak, Michael, Lifson, Jeffrey D., LaBranche, Celia C., Lackner, Andrew A., Keele, Brandon F., Maness, Nicholas J., Marsh, Mark, Hoxie, James A.
Publicado 2022