Single Mutation on Trastuzumab Modulates the Stability of Antibody–Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry

por Ferhati, Xhenti, Jiménez-Moreno, Ester, Hoyt, Emily A., Salluce, Giulia, Cabeza-Cabrerizo, Mar, Navo, Claudio D., Compañón, Ismael, Akkapeddi, Padma, Matos, Maria J., Salaverri, Noelia, Garrido, Pablo, Martínez, Alfredo, Laserna, Víctor, Murray, Thomas V., Jiménez-Osés, Gonzalo, Ravn, Peter, Bernardes, Gonçalo J. L., Corzana, Francisco
Publicado 2022