The Transmembrane Region Is Responsible for Targeting of Adaptor Protein LAX into “Heavy Rafts”

por Hrdinka, Matous, Otahal, Pavel, Horejsi, Vaclav
Publicado 2012

A Bird’s-Eye View of Cell Sources for Cell-Based Therapies in Blood Cancers

por Motais, Benjamin, Charvátová, Sandra, Hrdinka, Matouš, Šimíček, Michal, Jelínek, Tomáš, Ševčíková, Tereza, Kořístek, Zdeněk, Hájek, Roman, Bagó, Juli R.
Publicado 2020

Intercellular Mitochondrial Transfer in the Tumor Microenvironment

por Sahinbegovic, Hana, Jelinek, Tomas, Hrdinka, Matous, Bago, Juli R., Turi, Marcello, Sevcikova, Tereza, Kurtovic-Kozaric, Amina, Hajek, Roman, Simicek, Michal
Publicado 2020

Tuning CARs: recent advances in modulating chimeric antigen receptor (CAR) T cell activity for improved safety, efficacy, and flexibility

por Celichowski, Piotr, Turi, Marcello, Charvátová, Sandra, Radhakrishnan, Dhwani, Feizi, Neda, Chyra, Zuzana, Šimíček, Michal, Jelínek, Tomáš, Bago, Juli Rodriguez, Hájek, Roman, Hrdinka, Matouš
Publicado 2023

Normal Development and Function of T Cells in Proline Rich 7 (Prr7) Deficient Mice

por Hrdinka, Matous, Sudan, Kritika, Just, Sissy, Drobek, Ales, Stepanek, Ondrej, Schlüter, Dirk, Reinhold, Dirk, Jordan, Bryen A., Gintschel, Patricia, Schraven, Burkhart, Kreutz, Michael R.
Publicado 2016

CYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune Signaling

por Hrdinka, Matous, Fiil, Berthe Katrine, Zucca, Mattia, Leske, Derek, Bagola, Katrin, Yabal, Monica, Elliott, Paul R., Damgaard, Rune Busk, Komander, David, Jost, Philipp J., Gyrd-Hansen, Mads
Publicado 2016

Systematic analysis of the IL‐17 receptor signalosome reveals a robust regulatory feedback loop

por Draberova, Helena, Janusova, Sarka, Knizkova, Daniela, Semberova, Tereza, Pribikova, Michaela, Ujevic, Andrea, Harant, Karel, Knapkova, Sofija, Hrdinka, Matous, Fanfani, Viola, Stracquadanio, Giovanni, Drobek, Ales, Ruppova, Klara, Stepanek, Ondrej, Draber, Peter
Publicado 2020

The deubiquitinase OTUD1 regulates immunoglobulin production and proteasome inhibitor sensitivity in multiple myeloma

por Vdovin, Alexander, Jelinek, Tomas, Zihala, David, Sevcikova, Tereza, Durech, Michal, Sahinbegovic, Hana, Snaurova, Renata, Radhakrishnan, Dhwani, Turi, Marcello, Chyra, Zuzana, Popkova, Tereza, Venglar, Ondrej, Hrdinka, Matous, Hajek, Roman, Simicek, Michal
Publicado 2022

PB2397: TRANSCRIPTOME ANALYSIS OF DIFFUSE LARGE B-CELL LYMPHOMA CELLS EXPRESSING MYD88 L265P REVEALS CD44, LGALS3, NFKBIZ AND BATF AS DOWNSTREAM TARGETS OF ONCOGENIC NF-ΚB SIGNALIN...

por Turi, Marcello, Anilkumar Sithara, Anjana, Hofmanová, Lucie, Žihala, David, Radhakrishnan, Dhwani, Vdovin, Alexander, Knápková, Sofija, Ševčíková, Tereza, Chyra, Zuzana, Jelínek, Tomas, Šimíček, Michal, Gullà, Annamaria, Anderson, Kenneth, Hájek, Roman, Hrdinka, Matous
Publicado 2023

Selection, Expansion, and Unique Pretreatment of Allogeneic Human Natural Killer Cells with Anti-CD38 Monoclonal Antibody for Efficient Multiple Myeloma Treatment

por Motais, Benjamin, Charvátová, Sandra, Walek, Zuzana, Hrdinka, Matouš, Smolarczyk, Ryszard, Cichoń, Tomasz, Czapla, Justyna, Giebel, Sebastian, Šimíček, Michal, Jelínek, Tomáš, Ševčíková, Tereza, Sobotka, Jiří, Kořístek, Zdeněk, Hájek, Roman, Bagó, Juli R.
Publicado 2021

Transcriptome Analysis of Diffuse Large B-Cell Lymphoma Cells Inducibly Expressing MyD88 L265P Mutation Identifies Upregulated CD44, LGALS3, NFKBIZ, and BATF as Downstream Targets...

por Turi, Marcello, Anilkumar Sithara, Anjana, Hofmanová, Lucie, Žihala, David, Radhakrishnan, Dhwani, Vdovin, Alexander, Knápková, Sofija, Ševčíková, Tereza, Chyra, Zuzana, Jelínek, Tomáš, Šimíček, Michal, Gullà, Annamaria, Anderson, Kenneth Carl, Hájek, Roman, Hrdinka, Matouš
Publicado 2023

Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors

por Canning, Peter, Ruan, Qui, Schwerd, Tobias, Hrdinka, Matous, Maki, Jenny L., Saleh, Danish, Suebsuwong, Chalada, Ray, Soumya, Brennan, Paul E., Cuny, Gregory D., Uhlig, Holm H., Gyrd-Hansen, Mads, Degterev, Alexei, Bullock, Alex N.
Publicado 2015

SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling

por Elliott, Paul R., Leske, Derek, Hrdinka, Matous, Bagola, Katrin, Fiil, Berthe K., McLaughlin, Stephen H., Wagstaff, Jane, Volkmar, Norbert, Christianson, John C., Kessler, Benedikt M., Freund, Stefan M.V., Komander, David, Gyrd-Hansen, Mads
Publicado 2016

P805: EXTRAMEDULLARY MULTIPLE MYELOMA: MOLECULAR PATHOGENESIS AND NOVEL THERAPEUTIC TARGETS

por Zihala, David, Jelinek, Tomas, Sevcikova, Tereza, Anilkumar Sithara, Anjana, Kapustova, Veronika, Bilek, Daniel, Sahinbegovic, Hana, Popkova, Tereza, Plonkova, Hana, Broskevicova, Lucie, Venglar, Ondrej, Vrana, Jan, Zidlik, Vladimir, Havel, Martin, Koristek, Zdenek, Hrdinka, Matous, Chyra, Zuzana, Simicek, Michal, Hajek, Roman
Publicado 2023

Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling

por Hrdinka, Matous, Schlicher, Lisa, Dai, Bing, Pinkas, Daniel M, Bufton, Joshua C, Picaud, Sarah, Ward, Jennifer A, Rogers, Catherine, Suebsuwong, Chalada, Nikhar, Sameer, Cuny, Gregory D, Huber, Kilian VM, Filippakopoulos, Panagis, Bullock, Alex N, Degterev, Alexei, Gyrd‐Hansen, Mads
Publicado 2018

Mutation landscape of multiple myeloma measurable residual disease: identification of targets for precision medicine

por Zátopková, Martina, Ševčíková, Tereza, Fanfani, Viola, Chyra, Zuzana, Říhová, Lucie, Bezděková, Renata, Žihala, David, Growková, Kateřina, Filipová, Jana, Černá, Lucie, Broskevičova, Lucie, Kryukov, Fedor, Minařík, Jiří, Smejkalová, Jana, Maisnar, Vladimír, Harvanová, Ĺubica, Pour, Luděk, Jungova, Alexandra, Popková, Tereza, Bago, Juli Rodriguez, Anilkumar Sithara, Anjana, Hrdinka, Matouš, Jelínek, Tomáš, Šimíček, Michal, Stracquadanio, Giovanni, Hájek, Roman
Publicado 2022

More Than 2% of Circulating Tumor Plasma Cells Defines Plasma Cell Leukemia–Like Multiple Myeloma

por Jelinek, Tomas, Bezdekova, Renata, Zihala, David, Sevcikova, Tereza, Anilkumar Sithara, Anjana, Pospisilova, Lenka, Sevcikova, Sabina, Polackova, Petra, Stork, Martin, Knechtova, Zdenka, Venglar, Ondrej, Kapustova, Veronika, Popkova, Tereza, Muronova, Ludmila, Chyra, Zuzana, Hrdinka, Matous, Simicek, Michal, Garcés, Juan-Jose, Puig, Noemi, Cedena, Maria-Teresa, Jurczyszyn, Artur, Castillo, Jorge J., Penka, Miroslav, Radocha, Jakub, Mateos, Maria Victoria, San-Miguel, Jesús F., Paiva, Bruno, Pour, Ludek, Rihova, Lucie, Hajek, Roman
Publicado 2023

Heterogenous mutation spectrum and deregulated cellular pathways in aberrant plasma cells underline molecular pathology of light-chain amyloidosis

por Chyra, Zuzana, Sevcikova, Tereza, Vojta, Petr, Puterova, Janka, Brozova, Lucie, Growkova, Katerina, Filipova, Jana, Zatopkova, Martina, Grosicki, Sebastian, Barchnicka, Agnieszka, Wiktor-Jedrzejczak, Wieslaw, Waszczuk-Gajda, Anna, Jungova, Alexandra, Mikulasova, Aneta, Hajduch, Marian, Mokrejs, Martin, Pour, Ludek, Stork, Martin, Harvanova, Lubica, Mistrik, Martin, Mikala, Gabor, Robak, Pawel, Czyz, Anna, Debski, Jakub, Usnarska-Zubkiewicz, Lidia, Jurczyszyn, Artur, Stejskal, Lukas, Morgan, Gareth, Kryukov, Fedor, Budinska, Eva, Simicek, Michal, Jelinek, Tomas, Hrdinka, Matous, Hajek, Roman
Publicado 2020