Influence of Renal Function on Pharmacokinetics, Pharmacodynamics, and Safety of a Single Dose of Romosozumab

por Hsu, Cheng‐Pang, Maddox, Judy, Block, Geoffrey, Bartley, Yessenia, Yu, Zhigang
Publicado 2022

Non-human primates in the PKPD evaluation of biologics: Needs and options to reduce, refine, and replace. A BioSafe White Paper

por Ménochet, Karelle, Yu, Hongbin, Wang, Bonnie, Tibbitts, Jay, Hsu, Cheng-Pang, Kamath, Amrita V., Richter, Wolfgang F., Baumann, Andreas
Publicado 2022

Pharmacokinetic Drug‐Drug Interaction Study of Omecamtiv Mecarbil With Amiodarone and Digoxin in Healthy Subjects

por Trivedi, Ashit, Sohn, Winnie, Hsu, Cheng‐Pang, Jafarinasabian, Pegah, Zhang, Hanze, Hutton, Shauna, Flach, Stephen, Abbasi, Siddique, Dutta, Sandeep, Lee, Edward
Publicado 2021

Biodistribution, shedding, and transmissibility of the oncolytic virus talimogene laherparepvec in patients with melanoma

por Andtbacka, Robert H.I., Amatruda, Thomas, Nemunaitis, John, Zager, Jonathan S., Walker, John, Chesney, Jason A., Liu, Kate, Hsu, Cheng-Pang, Pickett, Cheryl A., Mehnert, Janice M.
Publicado 2019

The effect of different dosing regimens of motesanib on the gallbladder: a randomized phase 1b study in patients with advanced solid tumors

por Rosen, Lee S, Lipton, Lara, Price, Timothy J, Belman, Neil D, Boccia, Ralph V, Hurwitz, Herbert I, Stephenson Jr, Joe J, Wirth, Lori J, McCoy, Sheryl, Hei, Yong-jiang, Hsu, Cheng-Pang, Tebbutt, Niall C
Publicado 2013

A Phase 1, Randomized, Double-Blind, Single-Dose, Placebo-Controlled Safety, Tolerability, And Pharmacokinetic/Pharmacodynamic Study Of Evolocumab In Healthy Chinese Subjects

por Liu, Chao, Lu, Hong, Yuan, Fei, Chen, Wei-Li, Xu, Hong-Rong, Li, Hui, Hsu, Cheng-Pang, Egbuna, Ogo, Wu, Jihua, Dias, Clapton, Abosaleem, Bassam, Rana, Jitesh, Monsalvo, Maria Laura, Li, Xue-Ning, Yu, Zhigang
Publicado 2019