Characterization of SARS main protease and inhibitor assay using a fluorogenic substrate()

por Kuo, Chih-Jung, Chi, Ya-Hui, Hsu, John T.-A, Liang, Po-Huang
Publicado 2004

The Combination Effects of LiCl and the Active Leflunomide Metabolite, A771726, on Viral-Induced Interleukin 6 Production and EV-A71 Replication

por Hung, Hui-Chen, Shih, Shin-Ru, Chang, Teng-Yuan, Fang, Ming-Yu, Hsu, John T.-A.
Publicado 2014

Enhanced recombinant protein production and differential expression of molecular chaperones in sf-caspase-1-repressed stable cells after baculovirus infection

por Lai, Yiu-Kay, Hsu, John T-A, Chu, Chih-Chieh, Chang, Teng-Yuan, Pan, Kao-Lu, Lin, Chih-Chien
Publicado 2012

Non-small-cell lung cancer cells combat epidermal growth factor receptor tyrosine kinase inhibition through immediate adhesion-related responses

por Wang, Hsian-Yu, Hsu, Min-Kung, Wang, Kai-Hsuan, Tseng, Ching-Ping, Chen, Feng-Chi, Hsu, John T-A
Publicado 2016

Using mutagenesis to explore conserved residues in the RNA-binding groove of influenza A virus nucleoprotein for antiviral drug development

por Liu, Chia-Lin, Hung, Hui-Chen, Lo, Shou-Chen, Chiang, Ching-Hui, Chen, I-Jung, Hsu, John T.-A., Hou, Ming-Hon
Publicado 2016

Identification of danthron as an isoform-specific inhibitor of HEME OXYGENASE-1/cytochrome P450 reductase interaction with anti-tumor activity

por Chou, Yi-Tai, Hsu, Fu-Fei, Hu, Dun-Yao, Chen, Ying-Chih, Hsu, Yuan-Hao, Hsu, John T.-A., Chau, Lee-Young
Publicado 2018

Identification of Novel Cdc7 Kinase Inhibitors as Anti-Cancer Agents that Target the Interaction with Dbf4 by the Fragment Complementation and Drug Repositioning Approach

por Cheng, An Ning, Lo, Yu-Kang, Lin, Yi-Sheng, Tang, Tswen-Kei, Hsu, Chun-Hua, Hsu, John T.-A., Lee, Alan Yueh-Luen
Publicado 2018

Extracellular HSP90α Induces MyD88-IRAK Complex-Associated IKKα/β−NF-κB/IRF3 and JAK2/TYK2−STAT-3 Signaling in Macrophages for Tumor-Promoting M2-Polarization

por Fan, Chi-Shuan, Chen, Chia-Chi, Chen, Li-Li, Chua, Kee Voon, Hung, Hui-Chen, Hsu, John T. -A., Huang, Tze-Sing
Publicado 2022

Inhibition of SARS-CoV 3C-like Protease Activity by Theaflavin-3,3′-digallate (TF3)

por Chen, Chia-Nan, Lin, Coney P. C., Huang, Kuo-Kuei, Chen, Wei-Cheng, Hsieh, Hsin-Pang, Liang, Po-Huang, Hsu, John T.-A.
Publicado 2005

Evaluation of metal‐conjugated compounds as inhibitors of 3CL protease of SARS‐CoV

por Hsu, John T.-A., Kuo, Chih-Jung, Hsieh, Hsing-Pang, Wang, Yeau-Ching, Huang, Kuo-Kuei, Lin, Coney P.-C., Huang, Ping-Fang, Chen, Xin, Liang, Po-Huang
Publicado 2004

Identification of neuraminidase inhibitors against dual H274Y/I222R mutant strains

por Hsu, Kai-Cheng, Hung, Hui-Chen, HuangFu, Wei-Chun, Sung, Tzu-Ying, Eight Lin, Tony, Fang, Ming-Yu, Chen, I-Jung, Pathak, Nikhil, Hsu, John T.-A., Yang, Jinn-Moon
Publicado 2017

Aurintricarboxylic acid inhibits influenza virus neuraminidase

por Hung, Hui-Chen, Tseng, Ching-Ping, Yang, Jinn-Moon, Ju, Yi-Wei, Tseng, Sung-Nain, Chen, Yen-Fu, Chao, Yu-Sheng, Hsieh, Hsing-Pang, Shih, Shin-Ru, Hsu, John T.-A.
Publicado 2009

Design, synthesis, and evaluation of 3C protease inhibitors as anti-enterovirus 71 agents

por Kuo, Chih-Jung, Shie, Jiun-Jie, Fang, Jim-Min, Yen, Guei-Rung, Hsu, John T.-A., Liu, Hun-Ge, Tseng, Sung-Nain, Chang, Shih-Cheng, Lee, Ching-Yin, Shih, Shin-Ru, Liang, Po-Huang
Publicado 2008

Homology modeling of DFG-in FMS-like tyrosine kinase 3 (FLT3) and structure-based virtual screening for inhibitor identification

por Ke, Yi-Yu, Singh, Vivek Kumar, Coumar, Mohane Selvaraj, Hsu, Yung Chang, Wang, Wen-Chieh, Song, Jen-Shin, Chen, Chun-Hwa, Lin, Wen-Hsing, Wu, Szu-Huei, Hsu, John T. A., Shih, Chuan, Hsieh, Hsing-Pang
Publicado 2015

Anchor-based classification and type-C inhibitors for tyrosine kinases

por Hsu, Kai-Cheng, Sung, Tzu-Ying, Lin, Chih-Ta, Chiu, Yi-Yuan, Hsu, John T.-A., Hung, Hui-Chen, Sun, Chung-Ming, Barve, Indrajeet, Chen, Wen-Liang, Huang, Wen-Chien, Huang, Chin-Ting, Chen, Chun-Hwa, Yang, Jinn-Moon
Publicado 2015

Parallel Screening of Wild-Type and Drug-Resistant Targets for Anti-Resistance Neuraminidase Inhibitors

por Hsu, Kai-Cheng, Hung, Hui-Chen, Horng, Jim-Tong, Fang, Ming-Yu, Chang, Chun-Yu, Li, Ling-Ting, Chen, I-Jung, Chen, Yun-Chu, Chou, Ding-Li, Chang, Chun-Wei, Hsieh, Hsing-Pang, Yang, Jinn-Moon, Hsu, John T.-A.
Publicado 2013

Glucocorticoids may compromise the effect of gefitinib in non-small cell lung cancer

por Wang, Hsian-Yu, Chang, Yu-Ling, Cheng, Chun-Chun, Chao, Min-Wu, Lin, Su-I, Pan, Shiow-Lin, Hsu, Chih-Cheng, Liu, Tsang-Wu, Cheng, Han-Chin, Tseng, Ching-Ping, Liu, Shih-Jen, Tsai, Hui-Ju, Chang, Hsing-Yi, Hsu, John T.-A.
Publicado 2016

Evaluation of the Antitumor Effects of BPR1J-340, a Potent and Selective FLT3 Inhibitor, Alone or in Combination with an HDAC Inhibitor, Vorinostat, in AML Cancer

por Lin, Wen-Hsing, Yeh, Teng-Kuang, Jiaang, Weir-Torn, Yen, Kuei-Jung, Chen, Chun-Hwa, Huang, Chin-Ting, Yen, Shih-Chieh, Hsieh, Shu-Yi, Chou, Ling-Hui, Chen, Ching-Ping, Chiu, Chun-Hsien, Kao, Li-Chun, Chao, Yu-Sheng, Chen, Chiung-Tong, Hsu, John T.-A.
Publicado 2014

Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation

por Hsu, Yung Chang, Coumar, Mohane Selvaraj, Wang, Wen-Chieh, Shiao, Hui-Yi, Ke, Yi-Yu, Lin, Wen-Hsing, Kuo, Ching-Chuan, Chang, Chun-Wei, Kuo, Fu-Ming, Chen, Pei-Yi, Wang, Sing-Yi, Li, An-Siou, Chen, Chun-Hwa, Kuo, Po-Chu, Chen, Ching-Ping, Wu, Ming-Hsine, Huang, Chen-Lung, Yen, Kuei-Jung, Chang, Yun-I, Hsu, John T.-A., Chen, Chiung-Tong, Yeh, Teng-Kuang, Song, Jen-Shin
Publicado 2016