A PP1-binding motif present in BRCA1 plays a role in its DNA repair function

por Yu, Young-Mi, Pace, Serena M., Allen, Susan R., Deng, Chu-Xia, Hsu, Lih-Ching
Publicado 2008

Repurposing of nitroxoline as a potential anticancer agent against human prostate cancer – a crucial role on AMPK/mTOR signaling pathway and the interplay with Chk2 activation

por Chang, Wei-Ling, Hsu, Lih-Ching, Leu, Wohn-Jenn, Chen, Ching-Shih, Guh, Jih-Hwa
Publicado 2015

Discovery of New Glucose Uptake Inhibitors as Potential Anticancer Agents by Non-Radioactive Cell-Based Assays

por Hung, Hsueh-Chih, Li, Li-Cheng, Guh, Jih-Hwa, Kung, Fan-Lu, Hsu, Lih-Ching
Publicado 2022

Para-Toluenesulfonamide Induces Anti-tumor Activity Through Akt-Dependent and -Independent mTOR/p70S6K Pathway: Roles of Lipid Raft and Cholesterol Contents

por Hsu, Jui-Ling, Leu, Wohn-Jenn, Hsu, Lih-Ching, Liu, Shih-Ping, Zhong, Nan-Shan, Guh, Jih-Hwa
Publicado 2018

The Combination of MK-2206 and WZB117 Exerts a Synergistic Cytotoxic Effect Against Breast Cancer Cells

por Li, Yu-Liang, Weng, Hao-Cheng, Hsu, Jui-Ling, Lin, Shu-Wha, Guh, Jih-Hwa, Hsu, Lih-Ching
Publicado 2019

Phosphodiesterase Type 5 Inhibitors Synergize Vincristine in Killing Castration-Resistant Prostate Cancer Through Amplifying Mitotic Arrest Signaling

por Hsu, Jui-Ling, Leu, Wohn-Jenn, Hsu, Lih-Ching, Ho, Chen-Hsun, Liu, Shih-Ping, Guh, Jih-Hwa
Publicado 2020

Characterization of a fluorescent glucose derivative 1-NBDG and its application in the identification of natural SGLT1/2 inhibitors

por Kao, Ting-Yu, Wu, Hwa-Wei, Lee, Shoei-Sheng, Liang, Pi-Hui, Guh, Jih-Hwa, Hsu, Lih-Ching
Publicado 2021

The K898E germline variant in the PP1-binding motif of BRCA1 causes defects in DNA Repair

por Chen, Bert Yu-Hung, Huang, Cheng-Hsiang, Lin, Ying-Hsi, Huang, Ching-Chun, Deng, Chu-Xia, Hsu, Lih-Ching
Publicado 2014

Coordinate up-regulation of TMEM97 and cholesterol biosynthesis genes in normal ovarian surface epithelial cells treated with progesterone: implications for pathogenesis of ovarian...

por Wilcox, Cathy B, Feddes, Grace O, Willett-Brozick, Joan E, Hsu, Lih-Ching, DeLoia, Julie A, Baysal, Bora E
Publicado 2007

The Combination of a Novel GLUT1 Inhibitor and Cisplatin Synergistically Inhibits Breast Cancer Cell Growth By Enhancing the DNA Damaging Effect and Modulating the Akt/mTOR and MAP...

por Weng, Hao-Cheng, Sung, Chieh-Ju, Hsu, Jui-Ling, Leu, Wohn-Jenn, Guh, Jih-Hwa, Kung, Fan-Lu, Hsu, Lih-Ching
Publicado 2022

Reevesioside A, a Cardenolide Glycoside, Induces Anticancer Activity against Human Hormone-Refractory Prostate Cancers through Suppression of c-myc Expression and Induction of G1 A...

por Leu, Wohn-Jenn, Chang, Hsun-Shuo, Chan, She-Hung, Hsu, Jui-Ling, Yu, Chia-Chun, Hsu, Lih-Ching, Chen, Ih-Sheng, Guh, Jih-Hwa
Publicado 2014

The (+)-Brevipolide H Displays Anticancer Activity against Human Castration-Resistant Prostate Cancer: The Role of Oxidative Stress and Akt/mTOR/p70S6K-Dependent Pathways in G1 Che...

por Sheng, Yi-Hua, Leu, Wohn-Jenn, Chen, Ching-Nung, Hsu, Jui-Ling, Liu, Ying-Tung, Hsu, Lih-Ching, Hou, Duen-Ren, Guh, Jih-Hwa
Publicado 2020

Chalcones Display Anti-NLRP3 Inflammasome Activity in Macrophages through Inhibition of Both Priming and Activation Steps—Structure-Activity-Relationship and Mechanism Studies

por Leu, Wohn-Jenn, Chu, Jung-Chun, Hsu, Jui-Ling, Du, Chi-Min, Jiang, Yi-Huei, Hsu, Lih-Ching, Huang, Wei-Jan, Guh, Jih-Hwa
Publicado 2020

Anticancer Activity and Molecular Mechanisms of an Ursodeoxycholic Acid Methyl Ester-Dihydroartemisinin Hybrid via a Triazole Linkage in Hepatocellular Carcinoma Cells

por Hsu, Ya-Fen, Kung, Fan-Lu, Huang, Tzu-En, Deng, Yi-Ning, Guh, Jih-Hwa, Marchetti, Paolo, Marchesi, Elena, Perrone, Daniela, Navacchia, Maria Luisa, Hsu, Lih-Ching
Publicado 2023

Discovery of Novel Agents on Spindle Assembly Checkpoint to Sensitize Vinorelbine-Induced Mitotic Cell Death against Human Non-Small Cell Lung Cancers

por Chang, Ya-Ching, Tseng, Yu-Ling, Leu, Wohn-Jenn, Du, Chi-Min, Jiang, Yi-Huei, Hsu, Lih-Ching, Hsu, Jui-Ling, Hou, Duen-Ren, Guh, Jih-Hwa
Publicado 2020

Epi-reevesioside F inhibits Na(+)/K(+)-ATPase, causing cytosolic acidification, Bak activation and apoptosis in glioblastoma

por Hsu, Jui-Ling, Liu, Fan-Lun, Hsu, Lih-Ching, Chang, Hsun-Shuo, Leu, Wohn-Jenn, Yu, Chia-Chun, Chang, Wei-Ling, Chen, Ih-Sheng, Kung, Fan-Lu, Guh, Jih-Hwa
Publicado 2015

Phosphodiesterase Type 5 (PDE5) Inhibitors Sensitize Topoisomerase II Inhibitors in Killing Prostate Cancer Through PDE5-Independent Impairment of HR and NHEJ DNA Repair Systems

por Chang, Jo-Fan, Hsu, Jui-Ling, Sheng, Yi-Hua, Leu, Wohn-Jenn, Yu, Chia-Chun, Chan, She-Hung, Chan, Mei-Ling, Hsu, Lih-Ching, Liu, Shih-Ping, Guh, Jih-Hwa
Publicado 2019

Evaluation of the Anticancer Activity of a Bile Acid-Dihydroartemisinin Hybrid Ursodeoxycholic-Dihydroartemisinin in Hepatocellular Carcinoma Cells

por Huang, Tzu-En, Deng, Yi-Ning, Hsu, Jui-Ling, Leu, Wohn-Jenn, Marchesi, Elena, Capobianco, Massimo L., Marchetti, Paolo, Navacchia, Maria Luisa, Guh, Jih-Hwa, Perrone, Daniela, Hsu, Lih-Ching
Publicado 2020

Enantiomerically pure β-dipeptide derivative induces anticancer activity against human hormone-refractory prostate cancer through both PI3K/Akt-dependent and -independent pathways

por Chan, Mei-Ling, Yu, Chia-Chun, Hsu, Jui-Ling, Leu, Wohn-Jenn, Chan, She-Hung, Hsu, Lih-Ching, Liu, Shih-Ping, Ivantcova, Polina M., Dogan, Özdemir, Bräse, Stefan, Kudryavtsev, Konstantin V., Guh, Jih-Hwa
Publicado 2017

Non-immunosuppressive triazole-based small molecule induces anticancer activity against human hormone-refractory prostate cancers: the role in inhibition of PI3K/AKT/mTOR and c-Myc...

por Leu, Wohn-Jenn, Swain, Sharada Prasanna, Chan, She-Hung, Hsu, Jui-Ling, Liu, Shih-Ping, Chan, Mei-Ling, Yu, Chia-Chun, Hsu, Lih-Ching, Chou, Yen-Lin, Chang, Wei-Ling, Hou, Duen-Ren, Guh, Jih-Hwa
Publicado 2016