C9ORF72 suppresses JAK-STAT mediated inflammation

por Pang, Weilun, Hu, Fenghua
Publicado 2023

Spatiotemporal control of phosphatidylinositol 4-phosphate by Sac2 regulates endocytic recycling

por Hsu, FoSheng, Hu, Fenghua, Mao, Yuxin
Publicado 2015

SMCR8 negatively regulates AKT and MTORC1 signaling to modulate lysosome biogenesis and tissue homeostasis

por Lan, Yungang, Sullivan, Peter M., Hu, Fenghua
Publicado 2019

Regulation of lysosomal trafficking of progranulin by sortilin and prosaposin

por Du, Huan, Zhou, Xiaolai, Feng, Tuancheng, Hu, Fenghua
Publicado 2022

C-Terminus of Progranulin Interacts with the Beta-Propeller Region of Sortilin to Regulate Progranulin Trafficking

por Zheng, Yanqiu, Brady, Owen A., Meng, Peter S., Mao, Yuxin, Hu, Fenghua
Publicado 2011

Elevated TMEM106B levels exaggerate lipofuscin accumulation and lysosomal dysfunction in aged mice with progranulin deficiency

por Zhou, Xiaolai, Sun, Lirong, Brady, Owen Adam, Murphy, Kira A., Hu, Fenghua
Publicado 2017

Lysosomal processing of progranulin

por Zhou, Xiaolai, Paushter, Daniel H., Feng, Tuancheng, Sun, Lirong, Reinheckel, Thomas, Hu, Fenghua
Publicado 2017

Progranulin inhibits phospholipase sPLA2-IIA to control neuroinflammation

por Du, Huan, Yang, Cha, Nana, Alissa L., Seeley, William W., Smolka, Marcus, Hu, Fenghua
Publicado 2023

The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway

por Sullivan, Peter M., Zhou, Xiaolai, Robins, Adam M., Paushter, Daniel H., Kim, Dongsung, Smolka, Marcus B., Hu, Fenghua
Publicado 2016

Dextran-coated iron oxide nanoparticle-induced nanotoxicity in neuron cultures

por Badman, Ryan P., Moore, Shanna L., Killian, Jessica L., Feng, Tuancheng, Cleland, Thomas A., Hu, Fenghua, Wang, Michelle D.
Publicado 2020

Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin

por Zhou, Xiaolai, Sun, Lirong, Bastos de Oliveira, Francisco, Qi, Xiaoyang, Brown, William J., Smolka, Marcus B., Sun, Ying, Hu, Fenghua
Publicado 2015

A multifaceted role of progranulin in regulating amyloid-beta dynamics and responses

por Du, Huan, Wong, Man Ying, Zhang, Tingting, Santos, Mariela Nunez, Hsu, Charlene, Zhang, Junke, Yu, Haiyuan, Luo, Wenjie, Hu, Fenghua
Publicado 2021

Differential regulation of progranulin derived granulin peptides

por Zhang, Tingting, Du, Huan, Santos, Mariela Nunez, Wu, Xiaochun, Pagan, Mitchell D., Trigiani, Lianne Jillian, Nishimura, Nozomi, Reinheckel, Thomas, Hu, Fenghua
Publicado 2022

TMEM106B deficiency impairs cerebellar myelination and synaptic integrity with Purkinje cell loss

por Feng, Tuancheng, Luan, Lin, Katz, Isabel Iscol, Ullah, Mohammed, Van Deerlin, Vivianna M., Trojanowski, John Q., Lee, Edward B., Hu, Fenghua
Publicado 2022

Clinical features and viral etiology of acute respiratory infection in an outpatient fever clinic during COVID‐19 pandemic in a tertiary hospital in Nanjing, China

por Geng, Yu, Hao, Yingying, Xu, Xiaoming, Huang, Rui, He, Fei, Ni, Jun, Zhan, Jie, Chen, Yuxin, Hu, FengHua, Wu, Chao
Publicado 2022

CRISPR-Cas and catalytic hairpin assembly technology for target-initiated amplification detection of pancreatic cancer specific tsRNAs

por Wu, Jie, Xu, Hongpan, Hu, Fenghua, Jiang, Yiyue, Fan, Boyue, Khan, Adeel, Sun, Yifan, Di, Kaili, Gu, Xinrui, Shen, Han, Li, Zhiyang
Publicado 2023

Loss of TMEM106B and PGRN leads to severe lysosomal abnormalities and neurodegeneration in mice

por Feng, Tuancheng, Mai, Shuyi, Roscoe, Jenn Marie, Sheng, Rory R, Ullah, Mohammed, Zhang, Junke, Katz, Isabel Iscol, Yu, Haiyuan, Xiong, Wenjun, Hu, Fenghua
Publicado 2020

A longitudinal study of humoral immune responses induced by a 3-dose inactivated COVID-19 vaccine in an observational, prospective cohort

por Tao, Yue, Ma, Mengyin, Hu, Fenghua, Li, Ming, Geng, Yu, Wan, Yawen, Mao, Minxin, Chen, Lin, Shen, Ya, Zhu, Liguo, Shen, Han, Chen, Yuxin
Publicado 2022

Expression of TMEM106B, the frontotemporal lobar degeneration-associated protein, in normal and diseased human brain

por Busch, Johanna I, Martinez-Lage, Maria, Ashbridge, Emily, Grossman, Murray, Van Deerlin, Vivianna M, Hu, Fenghua, Lee, Virginia MY, Trojanowski, John Q, Chen-Plotkin, Alice S
Publicado 2013

Progranulin deficiency leads to reduced glucocerebrosidase activity

por Zhou, Xiaolai, Paushter, Daniel H., Pagan, Mitchell D., Kim, Dongsung, Nunez Santos, Mariela, Lieberman, Raquel L., Overkleeft, Herman S., Sun, Ying, Smolka, Marcus B., Hu, Fenghua
Publicado 2019