Function-based high-throughput screening for antibody antagonists and agonists against G protein-coupled receptors

por Ren, Huanhuan, Li, Jian, Zhang, Ning, Hu, Liaoyuan A., Ma, Yingli, Tagari, Philip, Xu, Jianqing, Zhang, Mei-Yun
Publicado 2020

Structure-guided discovery of a single-domain antibody agonist against human apelin receptor

por Ma, Yanbin, Ding, Yao, Song, Xianqiang, Ma, Xiaochuan, Li, Xun, Zhang, Ning, Song, Yunpeng, Sun, Yaping, Shen, Yuqing, Zhong, Wenge, Hu, Liaoyuan A., Ma, Yingli, Zhang, Mei-Yun
Publicado 2020

Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism

por Wang, Jia, Song, Xianqiang, Zhang, Dandan, Chen, Xiaoqing, Li, Xun, Sun, Yaping, Li, Cui, Song, Yunpeng, Ding, Yao, Ren, Ruobing, Harrington, Essa Hu, Hu, Liaoyuan A., Zhong, Wenge, Xu, Cen, Huang, Xin, Wang, Hong-Wei, Ma, Yingli
Publicado 2020

A general Fc engineering platform for the next generation of antibody therapeutics

por Chen, Da, Zhao, Yingjie, Li, Mingyu, Shang, Hang, Li, Na, Li, Fan, Wang, Wei, Wang, Yuan, Jin, Ruina, Liu, Shiyu, Li, Xun, Gao, Shan, Tian, Yujie, Li, Ruonan, Li, Huanhuan, Zhang, Yongyan, Du, Mingjuan, Cao, Youjia, Zhang, Yan, Li, Xin, Huang, Yi, Hu, Liaoyuan A., Li, Fubin, Zhang, Hongkai
Publicado 2021