Physiological activation of mGlu5 receptors supports the ion channel function of NMDA receptors in hippocampal LTD induction in vivo

por O’Riordan, Kenneth J., Hu, Neng-Wei, Rowan, Michael J.
Publicado 2018

Alzheimer’s disease Aβ assemblies mediating rapid disruption of synaptic plasticity and memory

por Klyubin, Igor, Cullen, William K, Hu, Neng-Wei, Rowan, Michael J
Publicado 2012

Pre-plaque Aß-Mediated Impairment of Synaptic Depotentiation in a Transgenic Rat Model of Alzheimer’s Disease Amyloidosis

por Qi, Yingjie, Klyubin, Igor, Hu, Neng-Wei, Ondrejcak, Tomas, Rowan, Michael J.
Publicado 2019

Enduring glucocorticoid-evoked exacerbation of synaptic plasticity disruption in male rats modelling early Alzheimer’s disease amyloidosis

por Qi, Yingjie, Klyubin, Igor, Ondrejcak, Tomas, Hu, Neng-Wei, Rowan, Michael J.
Publicado 2021

Extracellular Forms of Aβ and Tau from iPSC Models of Alzheimer’s Disease Disrupt Synaptic Plasticity

por Hu, Neng-Wei, Corbett, Grant T., Moore, Steven, Klyubin, Igor, O’Malley, Tiernan T., Walsh, Dominic M., Livesey, Frederick J., Rowan, Michael J.
Publicado 2018

Do tau-synaptic long-term depression interactions in the hippocampus play a pivotal role in the progression of Alzheimer’s disease?

por Hu, Zhengtao, Ondrejcak, Tomas, Yu, Pengpeng, Zhang, Yangyang, Yang, Yin, Klyubin, Igor, Kennelly, Sean P., Rowan, Michael J., Hu, Neng-Wei
Publicado 2022

Death-associated protein kinase 1 is associated with cognitive dysfunction in major depressive disorder

por Li, Xiao-Hui, Zhu, Hong-Can, Cui, Xue-Min, Wang, Wang, Yang, Lin, Wang, Li-Bo, Hu, Neng-Wei, Duan, Dong-Xiao
Publicado 2022

Long-Term Depression-Inducing Low Frequency Stimulation Enhances p-Tau181 and p-Tau217 in an Age-Dependent Manner in Live Rats

por Zhang, Yangyang, Yang, Yin, Hu, Zhengtao, Zhu, Manyi, Qin, Shuangying, Yu, Pengpeng, Li, Bo, Xu, Jitian, Ondrejcak, Tomas, Klyubin, Igor, Rowan, Michael J., Hu, Neng-Wei
Publicado 2022

mGlu5 receptors and cellular prion protein mediate amyloid-β-facilitated synaptic long-term depression in vivo

por Hu, Neng-Wei, Nicoll, Andrew J., Zhang, Dainan, Mably, Alexandra J., O’Malley, Tiernan, Purro, Silvia A., Terry, Cassandra, Collinge, John, Walsh, Dominic M., Rowan, Michael J.
Publicado 2014

Inhibition of the ISR abrogates mGluR5-dependent long-term depression and spatial memory deficits in a rat model of Alzheimer’s disease

por Hu, Zhengtao, Yu, Pengpeng, Zhang, Yangyang, Yang, Yin, Zhu, Manyi, Qin, Shuangying, Xu, Ji-Tian, Duan, Dongxiao, Wu, Yong, Wang, Deguo, Rowan, Michael J., Hu, Neng-Wei
Publicado 2022

Longitudinal testing of hippocampal plasticity reveals the onset and maintenance of endogenous human Aß-induced synaptic dysfunction in individual freely behaving pre-plaque transg...

por Qi, Yingjie, Klyubin, Igor, Harney, Sarah C, Hu, NengWei, Cullen, William K, Grant, Marianne K, Steffen, Julia, Wilson, Edward N, Do Carmo, Sonia, Remy, Stefan, Fuhrmann, Martin, Ashe, Karen H, Cuello, A Claudio, Rowan, Michael J
Publicado 2014