Nanopore tweezers measurements of RecQ conformational changes reveal the energy landscape of helicase motion

por Craig, Jonathan M, Mills, Maria, Kim, Hwanhee C, Huang, Jesse R, Abell, Sarah J, Mount, Jonathan W, Gundlach, Jens H, Neuman, Keir C, Laszlo, Andrew H
Publicado 2022

Nanopore molecular trajectories of a eukaryotic reverse transcriptase reveal a long-range RNA structure sensing mechanism

por Shaw, Alan, Craig, Jonathan M., Amiri, Hossein, Kim, Jeonghoon, Upton, Heather E., Pimentel, Sydney C., Huang, Jesse R., Marqusee, Susan, Collins, Kathleen, Gundlach, Jens H., Bustamante, Carlos J.
Publicado 2023

Observing inhibition of the SARS-CoV-2 helicase at single-nucleotide resolution

por Marx, Sinduja K, Mickolajczyk, Keith J, Craig, Jonathan M, Thomas, Christopher A, Pfeffer, Akira M, Abell, Sarah J, Carrasco, Jessica D, Franzi, Michaela C, Huang, Jesse R, Kim, Hwanhee C, Brinkerhoff, Henry, Kapoor, Tarun M, Gundlach, Jens H, Laszlo, Andrew H
Publicado 2023

Sequence-dependent mechanochemical coupling of helicase translocation and unwinding at single-nucleotide resolution

por Laszlo, Andrew H., Craig, Jonathan M., Gavrilov, Momčilo, Tippana, Ramreddy, Nova, Ian C., Huang, Jesse R., Kim, Hwanhee C., Abell, Sarah J., deCampos-Stairiker, Mallory, Mount, Jonathan W., Bowman, Jasmine L., Baker, Katherine S., Higinbotham, Hugh, Bobrovnikov, Dmitriy, Ha, Taekjip, Gundlach, Jens H.
Publicado 2022

Inhibition of the SARS-CoV-2 helicase at single-nucleotide resolution

por Marx, Sinduja K., Mickolajczyk, Keith J., Craig, Jonathan M., Thomas, Christopher A., Pfeffer, Akira M., Abell, Sarah J., Carrasco, Jessica D., Franzi, Michaela C., Huang, Jesse R., Kim, Hwanhee C., Brinkerhoff, Henry D., Kapoor, Tarun M., Gundlach, Jens H., Laszlo, Andrew H.
Publicado 2020