XIST lost induces ovarian cancer stem cells to acquire taxol resistance via a KMT2C-dependent way

por Huang, Ruili, Zhu, Lijuan, Zhang, Yali
Publicado 2020

High‐throughput screening assays for SARS‐CoV‐2 drug development: Current status and future directions

por Xu, Tuan, Zheng, Wei, Huang, Ruili
Publicado 2021

Use of Tox21 Screening Data to Evaluate the COVID-19 Drug Candidates for Their Potential Toxic Effects and Related Pathways

por Sakamuru, Srilatha, Huang, Ruili, Xia, Menghang
Publicado 2022

Application of dynamic topic models to toxicogenomics data

por Lee, Mikyung, Liu, Zhichao, Huang, Ruili, Tong, Weida
Publicado 2016

Performance of the BG1Luc ER TA Method in a qHTS Format

por Ceger, Patricia, Allen, David, Huang, Ruili, Xia, Menghang, Casey, Warren
Publicado 2015

A Grid Algorithm for High Throughput Fitting of Dose-Response Curve Data

por Wang, Yuhong, Jadhav, Ajit, Southal, Noel, Huang, Ruili, Nguyen, Dac-Trung
Publicado 2010

Repurposing drugs as COVID-19 therapies: A toxicity evaluation

por Ngan, Deborah K., Xu, Tuan, Xia, Menghang, Zheng, Wei, Huang, Ruili
Publicado 2022

PfCRT and PfMDR1 modulate interactions of artemisinin derivatives and ion channel blockers

por Eastman, Richard T., Khine, Pwint, Huang, Ruili, Thomas, Craig J., Su, Xin-zhuan
Publicado 2016

Unraveling Gene Fusions for Drug Repositioning in High-Risk Neuroblastoma

por Liu, Zhichao, Chen, Xi, Roberts, Ruth, Huang, Ruili, Mikailov, Mike, Tong, Weida
Publicado 2021

High-Throughput Chemical Screening and Structure-Based Models to Predict hERG Inhibition

por Krishna, Shagun, Borrel, Alexandre, Huang, Ruili, Zhao, Jinghua, Xia, Menghang, Kleinstreuer, Nicole
Publicado 2022

A Cell-Based β-Lactamase Reporter Gene Assay for the CREB Signaling Pathway

por Xia, Menghang, Guo, Vicky, Huang, Ruili, Inglese, James, Nirenberg, Marshall, Austin, Christopher P
Publicado 2009

Mechanism Profiling of Hepatotoxicity Caused by Oxidative Stress Using Antioxidant Response Element Reporter Gene Assay Models and Big Data

por Kim, Marlene Thai, Huang, Ruili, Sedykh, Alexander, Wang, Wenyi, Xia, Menghang, Zhu, Hao
Publicado 2015

Identification of Angiogenesis Inhibitors Using a Co-culture Cell Model in a High-Content and High-Throughput Screening Platform

por Li, Shuaizhang, Hsu, Chia-Wen, Sakamuru, Srilatha, Zou, Chaozhong, Huang, Ruili, Xia, Menghang
Publicado 2017

MON-032 Identification of Estrogen-Related Receptor Alpha Inhibitors from the Tox21 10K Compound Collection

por Lynch, Caitlin, Teng, Christina, Zhao, Jinghua, Huang, Ruili, Witt, Kristine, Merrick, B., Xia, Menghang
Publicado 2019

AI-based language models powering drug discovery and development

por Liu, Zhichao, Roberts, Ruth A., Lal-Nag, Madhu, Chen, Xi, Huang, Ruili, Tong, Weida
Publicado 2021

Exploring NCATS In-House Biomedical Data for Evidence-based Drug Repurposing

por Liu, Fang, Patt, Andrew, Chen, Chloe, Huang, Ruili, Xu, Yanji, Mathé, Ewy A., Zhu, Qian
Publicado 2023

Two High Throughput Screen Assays for Measurement of TNF-α in THP-1 Cells

por Leister, Kristin P, Huang, Ruili, Goodwin, Bonnie L, Chen, Andrew, Austin, Christopher P, Xia, Menghang
Publicado 2011

Bioactivity Signatures of Drugs vs. Environmental Chemicals Revealed by Tox21 High-Throughput Screening Assays

por Ngan, Deborah K., Ye, Lin, Wu, Leihong, Xia, Menghang, Rossoshek, Anna, Simeonov, Anton, Huang, Ruili
Publicado 2019

A gene expression biomarker for predictive toxicology to identify chemical modulators of NF-κB

por Korunes, Katharine L., Liu, Jie, Huang, Ruili, Xia, Menghang, Houck, Keith A., Corton, J. Christopher
Publicado 2022

Quantitative High-Throughput Identification of Drugs as Modulators of Human Constitutive Androstane Receptor

por Lynch, Caitlin, Zhao, Jinghua, Huang, Ruili, Xiao, Jingwei, Li, Linhao, Heyward, Scott, Xia, Menghang, Wang, Hongbing
Publicado 2015