SMARCE1 suppresses EGFR expression and controls responses to MET and ALK inhibitors in lung cancer

por Papadakis, Andreas I, Sun, Chong, Knijnenburg, Theo A, Xue, Yibo, Grernrum, Wipawadee, Hölzel, Michael, Nijkamp, Wouter, Wessels, Lodewyk FA, Beijersbergen, Roderick L, Bernards, Rene, Huang, Sidong
Publicado 2015

Genetic and Functional Studies Implicate Synaptic Overgrowth and Ring Gland cAMP/PKA Signaling Defects in the Drosophila melanogaster Neurofibromatosis-1 Growth Deficiency

por Walker, James A., Gouzi, Jean Y., Long, Jennifer B., Huang, Sidong, Maher, Robert C., Xia, Hongjing, Khalil, Kheyal, Ray, Arjun, Van Vactor, David, Bernards, René, Bernards, André
Publicado 2013

Aberration hubs in protein interaction networks highlight actionable targets in cancer

por Karimzadeh, Mehran, Jandaghi, Pouria, Papadakis, Andreas I., Trainor, Sebastian, Rung, Johan, Gonzàlez-Porta, Mar, Scelo, Ghislaine, Vasudev, Naveen S., Brazma, Alvis, Huang, Sidong, Banks, Rosamonde E., Lathrop, Mark, Najafabadi, Hamed S., Riazalhosseini, Yasser
Publicado 2018

A forward genetic screen identifies modifiers of rocaglate responsiveness

por Shen, Leo, Pugsley, Lauren, Cencic, Regina, Wang, HanChen, Robert, Francis, Naineni, Sai Kiran, Sahni, Ananya, Morin, Geneviève, Zhang, Wenhan, Nijnik, Anastasia, Porco, John A., Langlais, David, Huang, Sidong, Pelletier, Jerry
Publicado 2021

Resistance to different anthracycline chemotherapeutics elicits distinct and actionable primary metabolic dependencies in breast cancer

por McGuirk, Shawn, Audet-Delage, Yannick, Annis, Matthew G, Xue, Yibo, Vernier, Mathieu, Zhao, Kaiqiong, St-Louis, Catherine, Minarrieta, Lucía, Patten, David A, Morin, Geneviève, Greenwood, Celia MT, Giguère, Vincent, Huang, Sidong, Siegel, Peter M, St-Pierre, Julie
Publicado 2021

Author Correction: SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca(2+) flux to mitochondria

por Xue, Yibo, Morris, Jordan L., Yang, Kangning, Fu, Zheng, Zhu, Xianbing, Johnson, Fraser, Meehan, Brian, Witkowski, Leora, Yasmeen, Amber, Golenar, Tunde, Coatham, Mackenzie, Morin, Geneviève, Monast, Anie, Pilon, Virginie, Fiset, Pierre Olivier, Jung, Sungmi, Gonzalez, Anne V., Camilleri-Broet, Sophie, Fu, Lili, Postovit, Lynne-Marie, Spicer, Jonathan, Gotlieb, Walter H., Guiot, Marie-Christine, Rak, Janusz, Park, Morag, Lockwood, William, Foulkes, William D., Prudent, Julien, Huang, Sidong
Publicado 2023

Alanine supplementation exploits glutamine dependency induced by SMARCA4/2-loss

por Zhu, Xianbing, Fu, Zheng, Chen, Shary Y., Ong, Dionzie, Aceto, Giulio, Ho, Rebecca, Steinberger, Jutta, Monast, Anie, Pilon, Virginie, Li, Eunice, Ta, Monica, Ching, Kyle, Adams, Bianca N., Negri, Gian L., Choiniere, Luc, Fu, Lili, Pavlakis, Kitty, Pirrotte, Patrick, Avizonis, Daina Z., Trent, Jeffrey, Weissman, Bernard E., Klein Geltink, Ramon I., Morin, Gregg B., Park, Morag, Huntsman, David G., Foulkes, William D., Wang, Yemin, Huang, Sidong
Publicado 2023

SMARCA4 loss is synthetic lethal with CDK4/6 inhibition in non-small cell lung cancer

por Xue, Yibo, Meehan, Brian, Fu, Zheng, Wang, Xue Qing D., Fiset, Pierre Olivier, Rieker, Ralf, Levins, Cameron, Kong, Tim, Zhu, Xianbing, Morin, Geneviève, Skerritt, Lashanda, Herpel, Esther, Venneti, Sriram, Martinez, Daniel, Judkins, Alexander R., Jung, Sungmi, Camilleri-Broet, Sophie, Gonzalez, Anne V., Guiot, Marie-Christine, Lockwood, William W., Spicer, Jonathan D., Agaimy, Abbas, Pastor, William A., Dostie, Josée, Rak, Janusz, Foulkes, William D., Huang, Sidong
Publicado 2019

SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca(2+) flux to mitochondria

por Xue, Yibo, Morris, Jordan L., Yang, Kangning, Fu, Zheng, Zhu, Xianbing, Johnson, Fraser, Meehan, Brian, Witkowski, Leora, Yasmeen, Amber, Golenar, Tunde, Coatham, Mackenzie, Morin, Geneviève, Monast, Anie, Pilon, Virginie, Fiset, Pierre Olivier, Jung, Sungmi, Gonzalez, Anne V., Camilleri-Broet, Sophie, Fu, Lili, Postovit, Lynne-Marie, Spicer, Jonathan, Gotlieb, Walter H., Guiot, Marie-Christine, Rak, Janusz, Park, Morag, Lockwood, William, Foulkes, William D., Prudent, Julien, Huang, Sidong
Publicado 2021

CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary

por Xue, Yibo, Meehan, Brian, Macdonald, Elizabeth, Venneti, Sriram, Wang, Xue Qing D., Witkowski, Leora, Jelinic, Petar, Kong, Tim, Martinez, Daniel, Morin, Geneviève, Firlit, Michelle, Abedini, Atefeh, Johnson, Radia M., Cencic, Regina, Patibandla, Jay, Chen, Hongbo, Papadakis, Andreas I., Auguste, Aurelie, de Rink, Iris, Kerkhoven, Ron M., Bertos, Nicholas, Gotlieb, Walter H., Clarke, Blaise A., Leary, Alexandra, Witcher, Michael, Guiot, Marie-Christine, Pelletier, Jerry, Dostie, Josée, Park, Morag, Judkins, Alexander R., Hass, Ralf, Levine, Douglas A., Rak, Janusz, Vanderhyden, Barbara, Foulkes, William D., Huang, Sidong
Publicado 2019