Photopharmacology of Proteolysis-Targeting Chimeras: A New Frontier for Drug Discovery

por Zeng, Shenxin, Zhang, Hongjie, Shen, Zhengrong, Huang, Wenhai
Publicado 2021

Butein Inhibited In Vitro Hexokinase-2-Mediated Tumor Glycolysis in Hepatocellular Carcinoma by Blocking Epidermal Growth Factor Receptor (EGFR)

por Liao, Weirong, Liu, Jingtian, Zhang, Dawei, Huang, Wenhai, Chen, Runhao
Publicado 2018

Expression, Clinical Significance, Immune Infiltration, and Regulation Network of miR-3940-5p in Lung Adenocarcinoma Based on Bioinformatic Analysis and Experimental Validation

por Lin, Zhichao, Huang, Wenhai, Xie, Zehua, Yi, Yongsheng, Li, Zumei
Publicado 2022

The progress of molecules and strategies for the treatment of HBV infection

por Pan, Youlu, Xia, Heye, He, Yanwen, Zeng, Shenxin, Shen, Zhengrong, Huang, Wenhai
Publicado 2023

A hybrid energy-based and AI-based screening approach for the discovery of novel inhibitors of JAK3

por Wei, Juying, Pan, Youlu, Shen, Zheyuan, Shen, Liteng, Xu, Lei, Yu, Wenjuan, Huang, Wenhai
Publicado 2023

A Novel Diagnosis Method Based on Methylation Analysis of SHOX2 and Serum Biomarker for Early Stage Lung Cancer

por Huang, Wenhai, Huang, Hao, Zhang, Shuishen, Wang, Xueping, Ouyang, Juan, Lin, Zhichao, Chen, Peisong
Publicado 2020

LncRNA ADAMTS9-AS2 is a Prognostic Biomarker and Correlated with Immune Infiltrates in Lung Adenocarcinoma

por Lin, Zhichao, Huang, Wenhai, Yi, Yongsheng, Li, Dongbing, Xie, Zehua, Li, Zumei, Ye, Min
Publicado 2021

Identification of Novel Piperazinylquinoxaline Derivatives as Potent Phosphoinositide 3-Kinase (PI3K) Inhibitors

por Wu, Peng, Su, Yi, Guan, Xianghong, Liu, Xiaowen, Zhang, Jiankang, Dong, Xiaowu, Huang, Wenhai, Hu, Yongzhou
Publicado 2012

Discovery of novel coumarin derivatives as potent and orally bioavailable BRD4 inhibitors based on scaffold hopping

por Zhang, Zhimin, Gu, Lili, Wang, Beibei, Huang, Wenhai, Zhang, Yanmin, Ma, Zhen, Zeng, Shenxin, Shen, Zhengrong
Publicado 2019

Pleckstrin-2 as a Prognostic Factor and Mediator of Gastric Cancer Progression

por Wang, Jun, He, Zhigang, Sun, Bo, Huang, Wenhai, Xiang, Jianbin, Chen, Zongyou, Li, Zhenyang, Gu, Xiaodong
Publicado 2021

Hypoxia-Mimicking Cobalt-Doped Borosilicate Bioactive Glass Scaffolds with Enhanced Angiogenic and Osteogenic Capacity for Bone Regeneration

por Deng, Zhengwei, Lin, Bocai, Jiang, Zenghui, Huang, Wenhai, Li, Jiusheng, Zeng, Xiangqiong, Wang, Hui, Wang, Deping, Zhang, Yadong
Publicado 2019

Identification of probe-quality degraders for Poly(ADP-ribose) polymerase-1 (PARP-1)

por Zhang, Zhimin, Chang, Xinyue, Zhang, Chixiao, Zeng, Shenxin, Liang, Meihao, Ma, Zhen, Wang, Zunyuan, Huang, Wenhai, Shen, Zhengrong
Publicado 2020

Mesoporous bioactive glass-coated 3D printed borosilicate bioactive glass scaffolds for improving repair of bone defects

por Qi, Xin, Wang, Hui, Zhang, Yadong, Pang, Libin, Xiao, Wei, Jia, Weitao, Zhao, Shichang, Wang, Deping, Huang, Wenhai, Wang, Qiugen
Publicado 2018

Design, Synthesis and Evaluation of 3-(2-Aminoheterocycle)-4-benzyloxyphenylbenzamide Derivatives as BACE-1 Inhibitors

por Shangguan, Shihao, Wang, Fei, Liao, Yong, Yu, Haiping, Li, Jia, Huang, Wenhai, Hu, Haihong, Yu, Lushan, Hu, Yongzhou, Sheng, Rong
Publicado 2013

Design, Synthesis, and Bioactivity of Novel Bifunctional Small Molecules for Alzheimer’s disease

por Liang, Meihao, Gu, Lili, Zhang, Hongjie, Min, Jingli, Wang, Zunyuan, Ma, Zhen, Zhang, Chixiao, Zeng, Shenxin, Pan, Youlu, Yan, Dongmei, Shen, Zhengrong, Huang, Wenhai
Publicado 2022

(+)-JQ1 attenuated LPS-induced microglial inflammation via MAPK/NFκB signaling

por Wang, Huanhuan, Huang, Wenhai, Liang, Meihao, Shi, Yingying, Zhang, Chixiao, Li, Qin, Liu, Meng, Shou, Yikai, Yin, Hongping, Zhu, Xiaozheng, Sun, Xiaoyan, Hu, Yu, Shen, Zhengrong
Publicado 2018

Strontium modulates osteogenic activity of bone cement composed of bioactive borosilicate glass particles by activating Wnt/β-catenin signaling pathway

por Cui, Xu, Zhang, Yadong, Wang, Jianyun, Huang, Chengcheng, Wang, Yudong, Yang, Hongsheng, Liu, Wenlong, Wang, Ting, Wang, Deping, Wang, Guocheng, Ruan, Changshun, Chen, Dafu, Lu, William W., Huang, Wenhai, Rahaman, Mohamed N., Pan, Haobo
Publicado 2020

Phospholipid Phosphatase 4 promotes proliferation and tumorigenesis, and activates Ca(2+)-permeable Cationic Channel in lung carcinoma cells

por Zhang, Xin, Zhang, Lan, Lin, Bihua, Chai, Xingxing, Li, Ronggang, Liao, Yuehua, Deng, Xinghui, Liu, Qiongru, Yang, Wenli, Cai, Yubo, Zhou, Wei, Lin, Zhichao, Huang, Wenhai, Zhong, Meigong, Lei, Fangyong, Wu, Jinhua, Yu, Shuaishuai, Li, Xiaoping, Li, Shangren, Li, Yueyue, Zeng, Jincheng, Long, Wansheng, Ren, Dong, Huang, Yanming
Publicado 2017