Smad7 protects against chronic aristolochic acid nephropathy in mice

por Dai, Xiao-Yu, Zhou, Li, Huang, Xiao-Ru, Fu, Ping, Lan, Hui-Yao
Publicado 2015

The Regulatory T-cell Transcription Factor Foxp3 Protects against Crescentic Glomerulonephritis

por Yang, Chen, Huang, Xiao-Ru, Fung, Erik, Liu, Hua-Feng, Lan, Hui-Yao
Publicado 2017

Inflammatory stress in SARS-COV-2 associated Acute Kidney Injury

por Chen, Junzhe, Wang, Wenbiao, Tang, Ying, Huang, Xiao-ru, Yu, Xueqing, Lan, Hui-Yao
Publicado 2021

Diverse Role of TGF-β in Kidney Disease

por Gu, Yue-Yu, Liu, Xu-Sheng, Huang, Xiao-Ru, Yu, Xue-Qing, Lan, Hui-Yao
Publicado 2020

Transforming Growth Factor-β and Long Non-coding RNA in Renal Inflammation and Fibrosis

por Gu, Yue-Yu, Dou, Jing-Yun, Huang, Xiao-Ru, Liu, Xu-Sheng, Lan, Hui-Yao
Publicado 2021

Treatment of renal fibrosis by rebalancing TGF-β/Smad signaling with the combination of asiatic acid and naringenin

por Meng, Xiao-ming, Zhang, Yun, Huang, Xiao-Ru, Ren, Gui-ling, Li, Jun, Lan, Hui Yao
Publicado 2015

Treatment of Hypertensive Heart Disease by Targeting Smad3 Signaling in Mice

por Meng, Jinxiu, Qin, Yuyan, Chen, Junzhe, Wei, Lihua, Huang, Xiao-ru, Yu, Xiyong, Lan, Hui-yao
Publicado 2020

C-Reactive Protein Promotes Diabetic Kidney Disease in db/db Mice via the CD32b-Smad3-mTOR signaling Pathway

por You, Yong-Ke, Huang, Xiao-Ru, Chen, Hai-Yong, Lyu, Xia-Fei, Liu, Hua-Feng, Lan, Hui Y.
Publicado 2016

Inhibition of tumor invasion and metastasis by targeting TGF-β-Smad-MMP2 pathway with Asiatic acid and Naringenin

por Lian, Guang-Yu, Wang, Qing-Ming, Mak, Thomas Shiu-Kwong, Huang, Xiao-Ru, Yu, Xue-Qing, Lan, Hui-Yao
Publicado 2021

Regulatory role and mechanisms of myeloid TLR4 in anti-GBM glomerulonephritis

por Yang, Fuye, Chen, Jiaoyi, Huang, Xiao Ru, Yiu, Wai Han, Yu, Xueqing, Tang, Sydney C. W., Lan, Hui Yao
Publicado 2021

Single‐cell RNA Sequencing Identified Novel Nr4a1(+) Ear2(+) Anti‐Inflammatory Macrophage Phenotype under Myeloid‐TLR4 Dependent Regulation in Anti‐Glomerular Basement Membrane (GB...

por Chen, Jiaoyi, Huang, Xiao Ru, Yang, Fuye, Yiu, Wai Han, Yu, Xueqing, Tang, Sydney C. W., Lan, Hui Yao
Publicado 2022

Long Non-coding RNA LRNA9884 Promotes Acute Kidney Injury via Regulating NF-kB-Mediated Transcriptional Activation of MIF

por Zhang, Yingying, Tang, Patrick Ming-Kuen, Niu, Yangyang, García Córdoba, Cristina Alexandra, Huang, Xiao-Ru, Yu, Chen, Lan, Hui-Yao
Publicado 2020

Treatment with quercetin inhibits SARS-CoV-2 N protein-induced acute kidney injury by blocking Smad3-dependent G1 cell-cycle arrest

por Wu, Wenjing, Wang, Wenbiao, Liang, Liying, Chen, Junzhe, Wei, Biao, Huang, Xiao-Ru, Wang, Xiaoqin, Yu, Xueqing, Lan, Hui-Yao
Publicado 2023

Asiatic Acid Inhibits Liver Fibrosis by Blocking TGF-beta/Smad Signaling In Vivo and In Vitro

por Tang, Li-xia, He, Rui-hua, Yang, Guang, Tan, Jia-ju, Zhou, Li, Meng, Xiao-ming, Huang, Xiao Ru, Lan, Hui Yao
Publicado 2012

Chaihuang-Yishen Granule Inhibits Diabetic Kidney Disease in Rats through Blocking TGF-β/Smad3 Signaling

por Zhao, Ting Ting, Zhang, Hao Jun, Lu, Xiao Guang, Huang, Xiao Ru, Zhang, Wei Ku, Wang, Hua, Lan, Hui Yao, Li, Ping
Publicado 2014

Conditional knockout of TGF-βRII /Smad2 signals protects against acute renal injury by alleviating cell necroptosis, apoptosis and inflammation

por Yang, Qin, Ren, Gui-ling, Wei, Biao, Jin, Juan, Huang, Xiao Ru, Shao, Wei, Li, Jun, Meng, Xiao-ming, Lan, Hui Yao
Publicado 2019

Non-Coding RNAs as Biomarkers and Therapeutic Targets for Diabetic Kidney Disease

por Gu, Yue-Yu, Lu, Fu-Hua, Huang, Xiao-Ru, Zhang, Lei, Mao, Wei, Yu, Xue-Qing, Liu, Xu-Sheng, Lan, Hui-Yao
Publicado 2021

Inflammatory macrophages can transdifferentiate into myofibroblasts during renal fibrosis

por Meng, Xiao-Ming, Wang, Shuang, Huang, Xiao-Ru, Yang, Chen, Xiao, Jun, Zhang, Yang, To, Ka-Fai, Nikolic-Paterson, David J, Lan, Hui-Yao
Publicado 2016

Deletion of Smad3 protects against C-reactive protein-induced renal fibrosis and inflammation in obstructive nephropathy

por You, Yong-Ke, Wu, Wei-Feng, Huang, Xiao-Ru, Li, Hai-Di, Ren, Ye-Ping, Zeng, Jin-Cheng, Chen, Haiyong, Lan, Hui Yao
Publicado 2021

SARS-CoV-2 N protein induces acute kidney injury in diabetic mice via the Smad3-Ripk3/MLKL necroptosis pathway

por Liang, Liying, Wang, Wenbiao, Chen, Junzhe, Wu, Wenjing, Huang, Xiao-Ru, Wei, Biao, Zhong, Yu, Ma, Ronald C. W., Yu, Xueqing, Lan, Hui-Yao
Publicado 2023