Maximizing in vivo target clearance by design of pH-dependent target binding antibodies with altered affinity to FcRn

por Yang, Danlin, Giragossian, Craig, Castellano, Steven, Lasaro, Marcio, Xiao, Haiguang, Saraf, Himanshu, Hess Kenny, Cynthia, Rybina, Irina, Huang, Zhong-Fu, Ahlberg, Jennifer, Bigwarfe, Tammy, Myzithras, Maria, Waltz, Erica, Roberts, Simon, Kroe-Barrett, Rachel, Singh, Sanjaya
Publicado 2017

An adapted consensus protein design strategy for identifying globally optimal biotherapeutics

por Liu, Yanyun, Tsang, Kenny, Mays, Michelle, Hansen, Gale, Chiecko, Jeffrey, Crames, Maureen, Wei, Yangjie, Zhou, Weijie, Fredrick, Chase, Hu, James, Liu, Dongmei, Gebhard, Douglas, Huang, Zhong-Fu, Datar, Akshita, Kronkaitis, Anthony, Gueneva-Boucheva, Kristina, Seeliger, Daniel, Han, Fei, Sen, Saurabh, Kasturirangan, Srinath, Scheer, Justin M., Nixon, Andrew E., Panavas, Tadas, Marlow, Michael S., Kumar, Sandeep
Publicado 2022