Mechanistic Insights into Regulation of JAK2 Tyrosine Kinase

por Hubbard, Stevan R.
Publicado 2018

Structural Basis for the Interaction of the Adaptor Protein Grb14 with Activated Ras

por Qamra, Rohini, Hubbard, Stevan R.
Publicado 2013

Closing in on a mechanism for activation

por Hubbard, Stevan R, Miller, W Todd
Publicado 2014

Structural and functional studies of the Ras-associating and pleckstrin-homology domains of Grb10 and Grb14

por Depetris, Rafael S, Wu, Jinhua, Hubbard, Stevan R
Publicado 2009

Crystal structure of the C-terminal four-helix bundle of the potassium channel KCa3.1

por Ji, Tianyang, Corbalán-García, Senena, Hubbard, Stevan R.
Publicado 2018

Correction: Crystal structure of the C-terminal four-helix bundle of the potassium channel KCa3.1

por Ji, Tianyang, Corbalán-García, Senena, Hubbard, Stevan R.
Publicado 2018

Crystal structures of the Jak2 pseudokinase domain and the pathogenic mutant V617F

por Bandaranayake, Rajintha M., Ungureanu, Daniela, Shan, Yibing, Shaw, David E., Silvennoinen, Olli, Hubbard, Stevan R.
Publicado 2012

Structural basis of Janus kinase trans-activation

por Caveney, Nathanael A., Saxton, Robert A., Waghray, Deepa, Glassman, Caleb R., Tsutsumi, Naotaka, Hubbard, Stevan R., Christopher Garcia, K.
Publicado 2023

Identification of Novel Small Molecule Ligands for JAK2 Pseudokinase Domain

por Virtanen, Anniina T., Haikarainen, Teemu, Sampathkumar, Parthasarathy, Palmroth, Maaria, Liukkonen, Sanna, Liu, Jianping, Nekhotiaeva, Natalia, Hubbard, Stevan R., Silvennoinen, Olli
Publicado 2023

Rap1-interacting adapter molecule (RIAM) associates with the plasma membrane via a proximity detector

por Wynne, Joseph P., Wu, Jinhua, Su, Wenjuan, Mor, Adam, Patsoukis, Nikolaos, Boussiotis, Vassiliki A., Hubbard, Stevan R., Philips, Mark R.
Publicado 2012

Histidine phosphorylation relieves copper inhibition in the mammalian potassium channel KCa3.1

por Srivastava, Shekhar, Panda, Saswati, Li, Zhai, Fuhs, Stephen R, Hunter, Tony, Thiele, Dennis J, Hubbard, Stevan R, Skolnik, Edward Y
Publicado 2016

A DNA Sequence Recognition Loop on APOBEC3A Controls Substrate Specificity

por Logue, Eric C., Bloch, Nicolin, Dhuey, Erica, Zhang, Ruonan, Cao, Ping, Herate, Cecile, Chauveau, Lise, Hubbard, Stevan R., Landau, Nathaniel R.
Publicado 2014

Increased resistance of SARS-CoV-2 Omicron variant to neutralization by vaccine-elicited and therapeutic antibodies

por Tada, Takuya, Zhou, Hao, Dcosta, Belinda M., Samanovic, Marie I., Chivukula, Vidya, Herati, Ramin S., Hubbard, Stevan R., Mulligan, Mark J., Landau, Nathaniel R.
Publicado 2022

KRAS4A Directly Regulates Hexokinase 1

por Amendola, Caroline R., Mahaffey, James P., Parker, Seth J., Ahearn, Ian M., Chen, Wei-Ching, Zhou, Mo, Court, Helen, Shi, Jie, Mendoza, Sebastian L., Morten, Michael, Rothenberg, Eli, Gottlieb, Eyal, Wadghiri, Youssef Z., Possemato, Richard, Hubbard, Stevan R., Balmain, Allan, Kimmelman, Alec, Philips, Mark R.
Publicado 2019