Efficacy of SPI-1865, a novel gamma-secretase modulator, in multiple rodent models

por Loureiro, Robyn M, Dumin, Jo Ann, McKee, Timothy D, Austin, Wesley F, Fuller, Nathan O, Hubbs, Jed L, Shen, Ruichao, Jonker, Jeff, Ives, Jeff, Bronk, Brian S, Tate, Barbara
Publicado 2013

Modulation of Gamma-Secretase for the Treatment of Alzheimer's Disease

por Tate, Barbara, McKee, Timothy D., Loureiro, Robyn M. B., Dumin, Jo Ann, Xia, Weiming, Pojasek, Kevin, Austin, Wesley F., Fuller, Nathan O., Hubbs, Jed L., Shen, Ruichao, Jonker, Jeff, Ives, Jeff, Bronk, Brian S.
Publicado 2012

Itch suppression in mice and dogs by modulation of spinal α2 and α3GABA(A) receptors

por Ralvenius, William T., Neumann, Elena, Pagani, Martina, Acuña, Mario A., Wildner, Hendrik, Benke, Dietmar, Fischer, Nina, Rostaher, Ana, Schwager, Simon, Detmar, Michael, Frauenknecht, Katrin, Aguzzi, Adriano, Hubbs, Jed Lee, Rudolph, Uwe, Favrot, Claude, Zeilhofer, Hanns Ulrich
Publicado 2018

High-Content Small Molecule Screen Identifies a Novel Compound That Restores AP-4-Dependent Protein Trafficking in Neuronal Models of AP-4-Associated Hereditary Spastic Paraplegia

por Saffari, Afshin, Brechmann, Barbara, Boeger, Cedric, Saber, Wardiya Afshar, jumo, Hellen, Whye, Dosh, Wood, Delaney, Wahlster, Lara, Alecu, Julian, Ziegler, Marvin, Scheffold, Marlene, Winden, Kellen, Hubbs, Jed, Buttermore, Elizabeth, Barrett, Lee, Borner, Georg, Davies, Alexandra, Sahin, Mustafa, Ebrahimi-Fakhari, Darius
Publicado 2023