A TOX-ic axis of epigenetic stem cell maintenance and chemoresistance in colon cancer

por Hubert, Christopher G., Stauffer, Shaun R., Lathia, Justin D.
Publicado 2023

Three-dimensional organoid culture unveils resistance to clinical therapies in adult and pediatric glioblastoma

por Sundar, Swetha J., Shakya, Sajina, Barnett, Austin, Wallace, Lisa C., Jeon, Hyemin, Sloan, Andrew, Recinos, Violette, Hubert, Christopher G.
Publicado 2021

High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display

por Jarjour, Jordan, West-Foyle, Hoku, Certo, Michael T., Hubert, Christopher G., Doyle, Lindsey, Getz, Melissa M., Stoddard, Barry L., Scharenberg, Andrew M.
Publicado 2009

CDC20 maintains tumor initiating cells

por Xie, Qi, Wu, Qiulian, Mack, Stephen C., Yang, Kailin, Kim, Leo, Hubert, Christopher G., Flavahan, William A., Chu, Chengwei, Bao, Shideng, Rich, Jeremy N.
Publicado 2015

361 WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma

por Hubert, Christopher, Mitchell, Kelly, Sprowls, Samuel, Shakya, Sajina, Arora, Sonali, Silver, Daniel J., Goins, Christopher M., Wallace, Lisa, Roversi, Gustavo, Schafer, Rachel, Kay, Kristen, Miller, Tyler E., Lauko, Adam, Bassett, John, Kashyap, Anjali, Kass, J. D’Amato, Mulkearns-Hubert, Erin E., Johnson, Sadie, Alvarado, Joseph, Rich, Jeremy N., Paddison, Patrick J., Patel, Anoop P., Stauffer, Shaun R., Hubert, Christopher G., Lathia, Justin D.
Publicado 2023

Surgical resection of glioblastomas induces pleiotrophin-mediated self-renewal of glioblastoma stem cells in recurrent tumors

por Knudsen, Arnon Møldrup, Halle, Bo, Cédile, Oriane, Burton, Mark, Baun, Christina, Thisgaard, Helge, Anand, Atul, Hubert, Christopher, Thomassen, Mads, Michaelsen, Signe Regner, Olsen, Birgitte Brinkmann, Dahlrot, Rikke Hedegaard, Bjerkvig, Rolf, Lathia, Justin Durla, Kristensen, Bjarne Winther
Publicado 2021

Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches

por Shakya, Sajina, Gromovsky, Anthony D., Hale, James S., Knudsen, Arnon M., Prager, Briana, Wallace, Lisa C., Penalva, Luiz O. F., Brown, H. Alex, Kristensen, Bjarne W., Rich, Jeremy N., Lathia, Justin D., Brown, J. Mark, Hubert, Christopher G.
Publicado 2021

Zika virus has oncolytic activity against glioblastoma stem cells

por Zhu, Zhe, Gorman, Matthew J., McKenzie, Lisa D., Chai, Jiani N., Hubert, Christopher G., Prager, Briana C., Fernandez, Estefania, Richner, Justin M., Zhang, Rong, Shan, Chao, Tycksen, Eric, Wang, Xiuxing, Shi, Pei-Yong, Diamond, Michael S., Rich, Jeremy N., Chheda, Milan G.
Publicado 2017

Correction: Zika virus has oncolytic activity against glioblastoma stem cells

por Zhu, Zhe, Gorman, Matthew J., McKenzie, Lisa D., Chai, Jiani N., Hubert, Christopher G., Prager, Briana C., Fernandez, Estefania, Richner, Justin M., Zhang, Rong, Shan, Chao, Tycksen, Eric, Wang, Xiuxing, Shi, Pei-Yong, Diamond, Michael S., Rich, Jeremy N., Chheda, Milan G.
Publicado 2017

VRK1 Is a Synthetic–Lethal Target in VRK2-Deficient Glioblastoma

por Shields, Julie A., Meier, Samuel R., Bandi, Madhavi, Mulkearns-Hubert, Erin E., Hajdari, Nicole, Ferdinez, Maria Dam, Engel, Justin L., Silver, Daniel J., Shen, Binzhang, Zhang, Wenhai, Hubert, Christopher G., Mitchell, Kelly, Shakya, Sajina, Zhao, Shan-Chuan, Bejnood, Alborz, Zhang, Minjie, Tjin Tham Sjin, Robert, Wilker, Erik, Lathia, Justin D., Andersen, Jannik N., Chen, Yingnan, Li, Fang, Weber, Barbara, Huang, Alan, Emmanuel, Natasha
Publicado 2022

WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma

por Mitchell, Kelly, Sprowls, Samuel A., Arora, Sonali, Shakya, Sajina, Silver, Daniel J., Goins, Christopher M., Wallace, Lisa, Roversi, Gustavo, Schafer, Rachel E., Kay, Kristen, Miller, Tyler E., Lauko, Adam, Bassett, John, Kashyap, Anjali, D'Amato Kass, Jonathan, Mulkearns-Hubert, Erin E., Johnson, Sadie, Alvarado, Joseph, Rich, Jeremy N., Holland, Eric C., Paddison, Patrick J., Patel, Anoop P., Stauffer, Shaun R., Hubert, Christopher G., Lathia, Justin D.
Publicado 2023

Differential Connexin Function Enhances Self-Renewal in Glioblastoma

por Hitomi, Masahiro, Deleyrolle, Loic P., Mulkearns-Hubert, Erin E., Jarrar, Awad, Li, Meizhang, Sinyuk, Maksim, Otvos, Balint, Brunet, Sylvain, Flavahan, William A., Hubert, Christopher G., Goan, Winston, Hale, James S., Alvarado, Alvaro G., Zhang, Ao, Rohaus, Mark, Oli, Muna, Vedam-Mai, Vinata, Fortin, Jeff M., Futch, Hunter S., Griffith, Benjamin, Wu, Qiulian, Xia, Chunhong, Gong, Xiaohua, Ahluwalia, Manmeet S., Rich, Jeremy N., Reynolds, Brent A., Lathia, Justin D.
Publicado 2015

Transcription elongation factors represent in vivo cancer dependencies in glioblastoma

por Miller, Tyler E., Liau, Brian B., Wallace, Lisa C., Morton, Andrew R., Xie, Qi, Dixit, Deobrat, Factor, Daniel C., Kim, Leo J. Y., Morrow, James J., Wu, Qiulian, Mack, Stephen C., Hubert, Christopher G., Gillespie, Shawn M., Flavahan, William A., Hoffmann, Thomas, Thummalapalli, Rohit, Hemann, Michael T., Paddison, Patrick J., Horbinski, Craig M., Zuber, Johannes, Scacheri, Peter C., Bernstein, Bradley E., Tesar, Paul J., Rich, Jeremy N.
Publicado 2017

Therapeutic Targeting of Ependymoma as Informed by Oncogenic Enhancer Profiling

por Mack, Stephen C., Pajtler, Kristian W., Chavez, Lukas, Okonechnikov, Konstantin, Bertrand, Kelsey C., Wang, Xiuxing, Erkek, Serap, Federation, Alexander, Song, Anne, Lee, Christine, Wang, Xin, McDonald, Laura, Morrow, James J., Saiakhova, Alina, Sin-Chan, Patrick, Wu, Qiulian, Michaelraj, Antony, Miller, Tyler E., Hubert, Christopher G., Ryzhova, Marina, Garzia, Livia, Donovan, Laura, Dombrowski, Stephen, Factor, Daniel C., Luu, Betty, Valentim, Claudia L.L., Gimple, Ryan C., Morton, Andrew, Kim, Leo, Prager, Briana C., Lee, John J.Y., Wu, Xiaochong, Zuccaro, Jennifer, Thompson, Yuan, de Borja López Holgado, Francisco, Reimand, Juri, Ke, Susan Q., Tropper, Adam, Lai, Sisi, Vijayarajah, Senthuran, Doan, Sylvia, Mahadev, Vaidehi, Miñan, Ana Fernandez, Gröbner, Susanne N., Lienhard, Matthias, Zapatka, Marc, Huang, Zhiqin, Aldape, Kenneth D., Carcaboso, Angel M., Houghton, Peter J., Keir, Stephen T., Milde, Till, Witt, Hendrik, Li, Yan, Li, Chao-Jun, Bian, Xiu-Wu, Jones, David T.W., Scott, Ian, Singh, Sheila K., Huang, Annie, Dirks, Peter B., Bouffet, Eric, Bradner, James E., Ramaswamy, Vijay, Jabado, Nada, Rutka, James T., Northcott, Paul A., Lupien, Mathieu, Lichter, Peter, Korshunov, Andrey, Scacheri, Peter C., Pfister, Stefan M., Kool, Marcel, Taylor, Michael D., Rich, Jeremy N.
Publicado 2017