1-Hydroxy-2(1H)-pyridinone-Based Chelators with Potential Catechol O-Methyl Transferase Inhibition and Neurorescue Dual Action against Parkinson’s Disease

por Bergin, Joseph C. J., Tan, Kean Kan, Nelson, Anya K., Amarandei, Cristina-Andreea, Hubscher-Bruder, Véronique, Brandel, Jérémy, Voinarovska, Varvara, Dejaegere, Annick, Stote, Roland H., Tétard, David
Publicado 2022

Synthesis, physicochemical characterization and neuroprotective evaluation of novel 1-hydroxypyrazin-2(1H)-one iron chelators in an in vitro cell model of Parkinson's disease

por Lewis, Frank W., Bird, Kathleen, Navarro, Jean-Philippe, El Fallah, Rawa, Brandel, Jeremy, Hubscher-Bruder, Véronique, Tsatsanis, Andrew, Duce, James A., Tétard, David, Bourne, Samuel, Maina, Mahmoud, Pienaar, Ilse S.
Publicado 2022

Design and evaluation of bi-functional iron chelators for protection of dopaminergic neurons from toxicants

por Gutbier, Simon, Kyriakou, Sotiris, Schildknecht, Stefan, Ückert, Anna-Katharina, Brüll, Markus, Lewis, Frank, Dickens, David, Pearson, Liam, Elson, Joanna L., Michel, Sylvia, Hubscher-Bruder, Véronique, Brandel, Jeremy, Tetard, David, Leist, Marcel, Pienaar, Ilse S.
Publicado 2020