Replicative Stress and the FHIT Gene: Roles in Tumor Suppression, Genome Stability and Prevention of Carcinogenesis

por Karras, Jenna R., Paisie, Carolyn A., Huebner, Kay
Publicado 2014

The ubiquitous ‘cancer mutational signature’ 5 occurs specifically in cancers with deleted FHIT alleles

por Volinia, Stefano, Druck, Teresa, Paisie, Carolyn A., Schrock, Morgan S., Huebner, Kay
Publicado 2017

Impact of FHIT loss on the translation of cancer-associated mRNAs

por Kiss, Daniel L., Baez, William, Huebner, Kay, Bundschuh, Ralf, Schoenberg, Daniel R.
Publicado 2017

FHIT loss-induced DNA damage creates optimal APOBEC substrates: Insights into APOBEC-mediated mutagenesis

por Waters, Catherine E., Saldivar, Joshua C., Amin, Zaynab A., Schrock, Morgan S., Huebner, Kay
Publicado 2014

Loss of fragile histidine triad (Fhit) protein expression alters the translation of cancer-associated mRNAs

por Kiss, Daniel L., Baez, William D., Huebner, Kay, Bundschuh, Ralf, Schoenberg, Daniel R.
Publicado 2018

Fhit loss‐associated initiation and progression of neoplasia in vitro

por Karras, Jenna R., Schrock, Morgan S., Batar, Bahadir, Zhang, Jie, La Perle, Krista, Druck, Teresa, Huebner, Kay
Publicado 2016

Wwox Binding to the Murine Brca1-BRCT Domain Regulates Timing of Brip1 and CtIP Phospho-Protein Interactions with This Domain at DNA Double-Strand Breaks, and Repair Pathway Choice

por Park, Dongju, Gharghabi, Mehdi, Reczek, Colleen R., Plow, Rebecca, Yungvirt, Charles, Aldaz, C. Marcelo, Huebner, Kay
Publicado 2022

Common Fragile Site Tumor Suppressor Genes and Corresponding Mouse Models of Cancer

por Drusco, Alessandra, Pekarsky, Yuri, Costinean, Stefan, Antenucci, Anna, Conti, Laura, Volinia, Stefano, Aqeilan, Rami I., Huebner, Kay, Zanesi, Nicola
Publicado 2011

Zinc treatment reverses and anti-Zn-regulated miRs suppress esophageal carcinomas in vivo

por Fong, Louise Y., Huebner, Kay, Jing, Ruiyan, Smalley, Karl J., Brydges, Christopher R., Fiehn, Oliver, Farber, John L., Croce, Carlo M.
Publicado 2023

FHIT Suppresses Epithelial-Mesenchymal Transition (EMT) and Metastasis in Lung Cancer through Modulation of MicroRNAs

por Suh, Sung-Suk, Yoo, Ji Young, Cui, Ri, Kaur, Balveen, Huebner, Kay, Lee, Taek-Kyun, Aqeilan, Rami I., Croce, Carlo M.
Publicado 2014

Reduction in squamous cell carcinomas in mouse skin by dietary zinc supplementation

por Sun, Jin, Shen, Rulong, Schrock, Morgan S., Liu, James, Pan, Xueliang, Quimby, Donald, Zanesi, Nicola, Druck, Teresa, Fong, Louise Y., Huebner, Kay
Publicado 2016

Initiation of Genome Instability and Preneoplastic Processes through Loss of Fhit Expression

por Saldivar, Joshua C., Miuma, Satoshi, Bene, Jessica, Hosseini, Seyed Ali, Shibata, Hidetaka, Sun, Jin, Wheeler, Linda J., Mathews, Christopher K., Huebner, Kay
Publicado 2012

microRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers

por Gasparini, Pierluigi, Cascione, Luciano, Fassan, Matteo, Lovat, Francesca, Guler, Gulnur, Balci, Serdar, Irkkan, Cigdem, Morrison, Carl, Croce, Carlo M., Shapiro, Charles L., Huebner, Kay
Publicado 2014

Exome‐wide single‐base substitutions in tissues and derived cell lines of the constitutive Fhit knockout mouse

por Paisie, Carolyn A., Schrock, Morgan S., Karras, Jenna R., Zhang, Jie, Miuma, Satoshi, Ouda, Iman M., Waters, Catherine E., Saldivar, Joshua C., Druck, Teresa, Huebner, Kay
Publicado 2016

Integrated MicroRNA and mRNA Signatures Associated with Survival in Triple Negative Breast Cancer

por Cascione, Luciano, Gasparini, Pierluigi, Lovat, Francesca, Carasi, Stefania, Pulvirenti, Alfredo, Ferro, Alfredo, Alder, Hansjuerg, He, Gang, Vecchione, Andrea, Croce, Carlo M., Shapiro, Charles L., Huebner, Kay
Publicado 2013

Fhit Deficiency-Induced Global Genome Instability Promotes Mutation and Clonal Expansion

por Miuma, Satoshi, Saldivar, Joshua C., Karras, Jenna R., Waters, Catherine E., Paisie, Carolyn A., Wang, Yao, Jin, Victor, Sun, Jin, Druck, Teresa, Zhang, Jie, Huebner, Kay
Publicado 2013

Stem cell-related markers in primary breast cancers and associated metastatic lesions

por Guler, Gulnur, Balci, Serdar, Costinean, Stefan, Ussakli, Cigdem Himmetoglu, Irkkan, Cigdem, Suren, Dinc, Sari, Ebru, Altundag, Kadri, Ozisik, Yavuz, Jones, Susie, Bacher, Jason, Shapiro, Charles L., Huebner, Kay
Publicado 2012

Human-like hyperplastic prostate with low ZIP1 induced solely by Zn deficiency in rats

por Fong, Louise Y., Jing, Ruiyan, Smalley, Karl J., Wang, Zi-Xuan, Taccioli, Cristian, Fan, Sili, Chen, Hongping, Alder, Hansjuerg, Huebner, Kay, Farber, John L., Fiehn, Oliver, Croce, Carlo M.
Publicado 2018

Abrogation of esophageal carcinoma development in miR-31 knockout rats

por Fong, Louise Y., Taccioli, Cristian, Palamarchuk, Alexey, Tagliazucchi, Guidantonio Malagoli, Jing, Ruiyan, Smalley, Karl J., Fan, Sili, Altemus, Joseph, Fiehn, Oliver, Huebner, Kay, Farber, John L., Croce, Carlo M.
Publicado 2020

Androgen Receptor Status Is a Prognostic Marker in Non-Basal Triple Negative Breast Cancers and Determines Novel Therapeutic Options

por Gasparini, Pierluigi, Fassan, Matteo, Cascione, Luciano, Guler, Gulnur, Balci, Serdar, Irkkan, Cigdem, Paisie, Carolyn, Lovat, Francesca, Morrison, Carl, Zhang, Jianying, Scarpa, Aldo, Croce, Carlo M., Shapiro, Charles L., Huebner, Kay
Publicado 2014